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Author Details
Full Name
Michelle Haber
Affiliation
School of Clinical Medicine
ORCID
Career Start Year
1973
Papers
242
H Index
54
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36346110
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.
Int J Cancer
2023
37958555
Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.
Int J Mol Sci
2023
37523146
High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.
Cancer Res
2023
37511646
Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial.
J Pers Med
2023
37726477
Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives.
Br J Cancer
2023
37013636
A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.
Genome Med
2023
37196067
Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.
Sci Transl Med
2023
36656928
Heritable defects in telomere and mitotic function selectively predispose to sarcomas.
Science
2023
36882456
Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes.
Sci Rep
2023
36867694
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma.
Sci Adv
2023
34807782
Methodological advances in the discovery of novel neuroblastoma therapeutics.
Expert Opin Drug Discov
2022
35677155
The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Front Oncol
2022
35365224
Donor T cells for CAR T cell therapy.
Biomark Res
2022
35454786
Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer.
Cancers (Basel)
2022
36449545
Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors.
Proc Natl Acad Sci U S A
2022
35127484
Systematic <i>In Vitro</i> Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia.
Front Oncol
2022
35080351
GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators.
FEBS J
2022
34471258
Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.
Br J Cancer
2022
33310889
Targeted Therapy of <i>TERT</i>-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy.
Clin Cancer Res
2021
33852836
Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
Cell Rep
2021
33712556
Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.
Cell Death Dis
2021
33895784
Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia.
Leukemia
2021
33918978
A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma.
Cancers (Basel)
2021
33837299
Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.
Br J Cancer
2021
33658627
A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma.
Oncogene
2021
33579942
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.
Nat Commun
2021
33497018
The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma.
Mol Oncol
2021
34983733
Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition.
Drug Resist Updat
2021
34944614
Enhancing the Potential of Immunotherapy in Paediatric Sarcomas: Breaking the Immunosuppressive Barrier with Receptor Tyrosine Kinase Inhibitors.
Biomedicines
2021
34375680
Early-phenotype CAR-T cells for the treatment of pediatric cancers.
Ann Oncol
2021
34572932
Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma.
Cancers (Basel)
2021
34826366
A Primer for Assessing the Pathology in Mouse Models of Neuroblastoma.
Curr Protoc
2021
33994371
Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Clin Cancer Res
2021
34019301
Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules.
Methods Mol Biol
2021
34183305
Immunometabolism: A 'Hot' Switch for 'Cold' Pediatric Solid Tumors.
Trends Cancer
2021
33954150
Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy.
Immunotargets Ther
2021
31325323
Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia.
Int J Cancer
2020
31876116
Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.
Pediatr Blood Cancer
2020
31896781
OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.
Leukemia
2020
31862449
CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.
Biochem Pharmacol
2020
31919402
Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy.
Br J Cancer
2020
31848452
Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia.
Leukemia
2020
33144287
Recurrent <i>SPECC1L-NTRK</i> fusions in pediatric sarcoma and brain tumors.
Cold Spring Harb Mol Case Stud
2020
33139218
Corrigendum to: "MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma" [Biochim. Biophys. Acta, Gene Regul. Mech. 1861 (2018) 235-245].
Biochim Biophys Acta Gene Regul Mech
2020
33049203
Advances and Challenges in Pediatric and Childhood Cancers.
Cancer Cell
2020
32801162
Targeting TSLP-Induced Tyrosine Kinase Signaling Pathways in <i>CRLF2</i>-Rearranged Ph-like ALL.
Mol Cancer Res
2020
32651259
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.
Cancer Res
2020
32816860
Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion.
Cancer Res
2020
32123312
Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.
Oncogene
2020
32277480
ABCC4/MRP4 contributes to the aggressiveness of Myc-associated epithelial ovarian cancer.
Int J Cancer
2020
1 - 50 of 242
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Children's Cancer Institute, Lowy Cancer Research Centre
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34
Jamie I Fletcher
Co-authored papers
29
Chelsea Mayoh
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers
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David S Ziegler
Co-authored papers
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Richard B Lock
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers
20
Susan L Cohn
Co-authored papers
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Mark J Cowley
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers
11
Paul G Ekert
Co-authored papers
11
Vanessa Tyrrell
Lowy Cancer Research Centre, Children's Cancer Institute
Co-authored papers
10
Anna DeFazio
Westmead Hospital
Co-authored papers
7
Matthias Fischer
University Children's Hospital of Cologne
Co-authored papers
7
Maria Tsoli
Co-authored papers
6
Michael D Hogarty
Co-authored papers
6
David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers
6
John M Maris
Children's Hospital of Philadelphia
Co-authored papers
5
André Oberthuer
Co-authored papers
5
William A Weiss
University of California san francisco
Co-authored papers
5
Gudrun Schleiermacher
Institut Curie
Co-authored papers
5
Jonathan Beesley
QIMR Berghofer Medical Research Institute
Co-authored papers
4
Sharon E Johnatty
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Peter F Ambros
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