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Author Details

Owen J L Rackham
Duke-National University of Singapore
2010
57
26
PMIDPaper TitleJournal TitlePublished Year
36630908Deep learning models will shape the future of stem cell research.Stem Cell Reports2023
37587336Transient naive reprogramming corrects hiPS cells functionally and epigenetically.Nature2023
35759180LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide.J Cardiovasc Transl Res2023
36973261Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis.Nat Commun2023
36857629A single-cell atlas identifies pretreatment features of primary imatinib resistance in chronic myeloid leukemia.Blood2023
36271030A novel network pharmacology approach for leukaemia differentiation therapy using Mogrify<sup>®</sup>.Oncogene2022
35710627Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential.NPJ Regen Med2022
35652722CLIPreg: constructing translational regulatory networks from CLIP-, Ribo- and RNA-seq.Bioinformatics2022
35841888A high-resolution map of human RNA translation.Mol Cell2022
35730579PKN2 deficiency leads both to prenatal 'congenital' cardiomyopathy and defective angiotensin II stress responses.Biochem J2022
33440181Challenges for Computational Stem Cell Biology: A Discussion for the Field.Stem Cell Reports2021
33625849Evaluating Capture Sequence Performance for Single-Cell CRISPR Activation Experiments.ACS Synth Biol2021
33731926Modelling human blastocysts by reprogramming fibroblasts into iBlastoids.Nature2021
33837217Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity.Nat Commun2021
33774659ShinyCell: simple and sharable visualization of single-cell gene expression data.Bioinformatics2021
34786712Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.Ann N Y Acad Sci2021
34021136Transcriptional signature in microglia associated with Aβ plaque phagocytosis.Nat Commun2021
33417869Computational Stem Cell Biology: Open Questions and Guiding Principles.Cell Stem Cell2021
32939092Reprogramming roadmap reveals route to human induced trophoblast stem cells.Nature2020
32058565GeneSwitches: ordering gene expression and functional events in single-cell experiments.Bioinformatics2020
31919106Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy.J Am Soc Nephrol2020
33038298EpiMogrify Models H3K4me3 Data to Identify Signaling Molecules that Improve Cell Fate Control and Maintenance.Cell Syst2020
30545825Let it RE:IN: integrating experimental observations to predict pluripotency network behaviour.EMBO J2019
31857479Potassium channel dysfunction in human neuronal models of Angelman syndrome.Science2019
31768052A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation.Nat Neurosci2019
31763789deltaTE: Detection of Translationally Regulated Genes by Integrative Analysis of Ribo-seq and RNA-seq Data.Curr Protoc Mol Biol2019
31501434Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.Nat Commun2019
31290135Correction to: Molecular Interaction Networks to Select Factors for Cell Conversion.Methods Mol Biol2019
31399586WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.Nat Commun2019
31284728Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.Circulation2019
31420939Integrated systems-genetic analyses reveal a network target for delaying glioma progression.Ann Clin Transl Neurol2019
31062318Molecular Interaction Networks to Select Factors for Cell Conversion.Methods Mol Biol2019
27869827Titin-truncating variants affect heart function in disease cohorts and the general population.Nat Genet2017
28213474A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation.Genetics2017
28241135An atlas of human long non-coding RNAs with accurate 5' ends.Nature2017
29212013Cell Type of Origin Dictates the Route to Pluripotency.Cell Rep2017
29160304IL-11 is a crucial determinant of cardiovascular fibrosis.Nature2017
29038337RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.Mol Syst Biol2017
27794045Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals.Nucleic Acids Res2017
26691832Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease.Nat Neurosci2016
26490503Web-based Gene Pathogenicity Analysis (WGPA): a web platform to interpret gene pathogenicity from personal genome data.Bioinformatics2016
27736295Computational methods for direct cell conversion.Cell Cycle2016
26780608A predictive computational framework for direct reprogramming between human cell types.Nat Genet2016
25339269A proteome quality index.Environ Microbiol2015
25980317Function-selective domain architecture plasticity potentials in eukaryotic genome evolution.Biochimie2015
25777524WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools.Bioinformatics2015
25414345The SUPERFAMILY 1.75 database in 2014: a doubling of data.Nucleic Acids Res2015
25550428EvoTol: a protein-sequence based evolutionary intolerance framework for disease-gene prioritization.Nucleic Acids Res2015
25348407Genome3D: exploiting structure to help users understand their sequences.Nucleic Acids Res2015
24692656The evolution of human cells in terms of protein innovation.Mol Biol Evol2014
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Collaborators

Julian Gough
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 16
Sebastian Schafer
Co-authored papers 10
Hai Fang
University of Bristol
Co-authored papers 8
Stuart A Cook
Co-authored papers 8
Norbert H??bner
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 7
Matt E Oates
University of Bristol
Co-authored papers 7
Ryan Lister
Co-authored papers 7
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Yoshihide Hayashizaki
Center for Integrative Medical Sciences
Co-authored papers 5
Leonardo Bottolo
University of Cambridge
Co-authored papers 5
Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 4
Christine A Wells
The University of Melbourne
Co-authored papers 4
Harukazu Suzuki
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Paul J R Barton
Co-authored papers 4
Piero Carninci
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Robin Andersson
University of Copenhagen
Co-authored papers 3
Alexander Maxwell Burroughs
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 3
Jessica Severin
Center for Integrative Medical Sciences
Co-authored papers 3
Nicolas Bertin
University Bordeaux, CNRS
Co-authored papers 3
Timo Lassmann
Telethon Kids Institute, University of Western Australia
Co-authored papers 3
Albin Sandelin
University of Copenhagen
Co-authored papers 3
Takeya Kasukawa
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Marina Lizio
Cerevance Ltd
Co-authored papers 3
Jayson Harshbarger
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Yulia A Medvedeva
Research Center of Biotechnology RAS, Russian Academy of Sciences
Co-authored papers 3
Andreas Lennartsson
Karolinska Institute
Co-authored papers 3
Leanne E Felkin
Co-authored papers 3
Cyrus Chothia
Co-authored papers 3
Peter Heutink
German Center for Neurodegenerative Diseases (DZNE).
Co-authored papers 3
Release 1.2