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Author Details

Steven C Clifford
Wolfson Childhood Cancer Research Centre, Newcastle University Centre for Cancer
1994
135
52
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36631900Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.Acta Neuropathol Commun2023
37573504Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray.STAR Protoc2023
37021628Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development.Neuropathol Appl Neurobiol2023
37014508Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification.Acta Neuropathol2023
37379234Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.Neuro Oncol2023
36548930Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study.J Clin Oncol2023
36869047ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.Nat Commun2023
34272868Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse.Neuro Oncol2022
35379950Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.Cell Death Differ2022
35831448Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development.Acta Neuropathol2022
35816899Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma.EBioMedicine2022
35926460Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development.Cell Rep2022
36219398Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma.Cancer Res2022
36252166How Can Genomic Innovations in Pediatric Brain Tumors Transform Outcomes in Low- and Middle-Income Countries?JCO Glob Oncol2022
35053536Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial.Cancers (Basel)2022
32779246The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes.Neuropathol Appl Neurobiol2021
33826763Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics.Neuropathol Appl Neurobiol2021
33763695Corrigendum: Contrasting effects on HIF-1α regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.Hum Mol Genet2021
33846320Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation.Nat Commun2021
33662447Inter and intra-tumoral heterogeneity as a platform for personalized therapies in medulloblastoma.Pharmacol Ther2021
35008290Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment.Cancers (Basel)2021
34885186SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma.Cancers (Basel)2021
34993501PCR amplicons identify widespread copy number variation in human centromeric arrays and instability in cancer.Cell Genom2021
34556677Combining multi-site magnetic resonance imaging with machine learning predicts survival in pediatric brain tumors.Sci Rep2021
34078638Acceptance and commitment therapy for young brain tumour survivors: study protocol for an acceptability and feasibility trial.BMJ Open2021
32859926Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity.Nat Commun2020
31786093DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.Lancet Child Adolesc Health2020
31924815The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma.Sci Rep2020
31952041Effects of the growth pattern of medulloblastoma on short-term neurological impairments after surgery: results from the prospective multicenter HIT-SIOP PNET 4 study.J Neurosurg Pediatr2020
33288846Author Correction: VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells.Commun Biol2020
33222802Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study.Lancet Child Adolesc Health2020
33305077Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma - A Report From the HIT 2000 Trial.Adv Radiat Oncol2020
33067561VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells.Commun Biol2020
31076851Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes.Acta Neuropathol2019
31797797EANO-EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma.Lancet Oncol2019
31416846Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma.Cancer Res2019
30765705Medulloblastoma.Nat Rev Dis Primers2019
30392813Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial.Lancet Oncol2018
30102236Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group.Lancet Oncol2018
28011926Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data.Neuro Oncol2017
29044166Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures.Sci Rep2017
29340109Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours.Oncotarget2017
28971956TAp73 is a marker of glutamine addiction in medulloblastoma.Genes Dev2017
28545823Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study.Lancet Oncol2017
27110286Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.Ecancermedicalscience2016
27423645Relapse patterns and outcome after relapse in standard risk medulloblastoma: a report from the HIT-SIOP-PNET4 study.J Neurooncol2016
27229157DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas.Acta Neuropathol Commun2016
27040285Risk stratification of childhood medulloblastoma in the molecular era: the current consensus.Acta Neuropathol2016
26760213Divergent clonal selection dominates medulloblastoma at recurrence.Nature2016
25531316Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance.Oncogene2015
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Uri Tabori
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Katja von Hoff
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Release 1.2