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Author Details

Hyun-Sik Yang
Massachusetts General Hospital, the Gordon Center for Medical Imaging
2011
43
20
PMIDPaper TitleJournal TitlePublished Year
36892007Utility of Amyloid Positron Emission Tomography Imaging in Older Adults With Epilepsy and Cognitive Decline.Am J Alzheimers Dis Other Demen2023
37968130Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults.Neurology2023
37612284Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer's disease.Nat Commun2023
37536975Using community-based geographical information system (GIS) to recruit older Asian Americans in an Alzheimer's disease study.BMJ Open2023
38036535Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.Nat Commun2023
36993271Novel <i>CYP1B1-RMDN2</i> Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.medRxiv2023
37020050Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau.Mol Psychiatry2023
36945609Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer's disease.bioRxiv2023
37336975Multicellular communities are perturbed in the aging human brain and Alzheimer's disease.Nat Neurosci2023
37333223Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.medRxiv2023
36512061LATE-NC staging in routine neuropathologic diagnosis: an update.Acta Neuropathol2023
34160128Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults.Alzheimers Dement2022
35710160Human Genetics Clarifies the Relationship Between Depression and Alzheimer's Disease.Biol Psychiatry2022
35473760Association of β-Amyloid and Vascular Risk on Longitudinal Patterns of Brain Atrophy.Neurology2022
35821672Physical activity is associated with increased resting-state functional connectivity in networks predictive of cognitive decline in clinically unimpaired older adults.Alzheimers Dement (Amst)2022
35552371Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.Brain2022
35880989Tau Mediates Synergistic Influence of Vascular Risk and Aβ on Cognitive Decline.Ann Neurol2022
35105862Brain microRNAs are associated with variation in cognitive trajectory in advanced age.Transl Psychiatry2022
34742335Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain.Mol Neurodegener2021
33610961KLâ¿¿VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOEâ¿¿4 carriers.Neurobiol Aging2021
32568366Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.JAMA Neurol2020
33247134Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals.Nat Commun2020
32877673Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.Cell Rep2020
32844198Genetic variants and functional pathways associated with resilience to Alzheimer's disease.Brain2020
32249013Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults.Neurobiol Aging2020
32526197Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.Neuron2020
30565287Vascular Risk and β-Amyloid Are Synergistically Associated with Cortical Tau.Ann Neurol2019
31312836Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults.JAMA Neurol2019
31397865Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults.JAMA Netw Open2019
30883345An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults.J Alzheimers Dis2019
30549303The impact of amyloid-beta and tau on prospective cognitive decline in older individuals.Ann Neurol2019
29765395Progressive Neurological Decline with Deep Bilateral Imaging Changes: A Protean Presentation of Dural Arteriovenous Fistulae.Interv Neurol2018
29799986Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study.JAMA Neurol2018
30093249Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study.Lancet Neurol2018
30258235Deconstructing and targeting the genomic architecture of human neurodegeneration.Nat Neurosci2018
30374196Neurogenetic contributions to amyloid beta and tau spreading in the human cortex.Nat Med2018
28761931<i>UNC5C</i> variants are associated with cerebral amyloid angiopathy.Neurol Genet2017
28441426Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.PLoS Med2017
28783770Active 46-year-old man with right-sided visual loss and no family history of stroke · Dx?J Fam Pract2017
24799521Teaching NeuroImages: brain mass with hilar adenopathy: the importance of histologic diagnosis.Neurology2014
21911039The rubrospinal tract in the human brain: diffusion tensor imaging study.Neurosci Lett2011
21876027Use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers and cancer risk: a meta-analysis of observational studies.CMAJ2011
22080892Effect of obesity on survival of women with epithelial ovarian cancer: a systematic review and meta-analysis of observational studies.Int J Gynecol Cancer2011
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Collaborators

Reisa A Sperling
Brigham and Women's Hospital, Massachusetts General Hospital
Co-authored papers 25
Keith A Johnson
Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 18
David A Bennett
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Co-authored papers 17
Philip L De Jager
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Co-authored papers 15
Charles C White
University of Tennessee College of Medicine Chattanooga
Co-authored papers 8
Gad A Marshall
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 7
Hans-Ulrich Klein
Columbia University Irving Medical Center
Co-authored papers 6
Logan Dumitrescu
Vanderbilt University Medical Center
Co-authored papers 5
Bernard Hanseeuw
Gordon Center for Medical Imaging, Massachusetts General Hospital
Co-authored papers 5
Andrew J Saykin
Indiana University School of Medicine
Co-authored papers 4
Anand Viswanathan
Massachusetts General Hospital, Harvard Medical School
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Li-San Wang
Co-authored papers 3
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The University of Michigan ann arbor
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Lori B Chibnik
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Lei Yu
Rush University Medical Center
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Badri N Vardarajan
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Christopher Dirk Keene
University of Washington
Co-authored papers 3
Kwangsik Nho
Indiana University School of Medicine
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Nancy J Cox
Vanderbilt University Medical Center
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Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 2
William S Bush
Cleveland Institute for Computational Biology, Case Western Reserve University
Co-authored papers 2
David W Fardo
University of Kentucky
Co-authored papers 2
William J Jagust
Helen Wills Neuroscience Institute, University of California Berkeley
Co-authored papers 2
Georges El Fakhri
Massachusetts General Hospital, the Gordon Center for Medical Imaging
Co-authored papers 2
Douglas M Ruderfer
Vanderbilt University Medical Center
Co-authored papers 2
Margaret A Pericak-Vance
Co-authored papers 2
Heidi I L Jacobs
Maastricht University
Co-authored papers 2
Lindsay A Farrer
Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 2
Gerard D Schellenberg
Co-authored papers 2
Eric B Larson
University of Washington
Co-authored papers 2
Release 1.2