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Author Details
Full Name
Sriram Kosuri
Affiliation
Octant Inc.
ORCID
Career Start Year
2005
Papers
31
H Index
20
Expertise
CM4AI Collaborator
Prashant Mali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37214829
Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters.
bioRxiv
2023
37532706
A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design.
Nat Commun
2023
35981026
Functional regulatory variants implicate distinct transcriptional networks in dementia.
Science
2022
32511368
SwabExpress: An end-to-end protocol for extraction-free COVID-19 testing.
bioRxiv
2021
34211145
Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples.
Nat Biomed Eng
2021
34286830
SwabExpress: An End-to-End Protocol for Extraction-Free COVID-19 Testing.
Clin Chem
2021
33436562
Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems.
Nat Commun
2021
32603702
Dissection of c-AMP Response Element Architecture by Using Genomic and Episomal Massively Parallel Reporter Assays.
Cell Syst
2020
33303831
Reliable and accurate diagnostics from highly multiplexed sequencing assays.
Sci Rep
2020
33179598
Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross.
Elife
2020
29388765
Systematic Dissection of Sequence Elements Controlling Ͽ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia coli.
Biochemistry
2019
30904378
A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing.
Cell Syst
2019
30503770
A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions.
Mol Cell
2019
29301959
Multiplexed gene synthesis in emulsions for exploring protein functional landscapes.
Science
2018
30052624
Metagenomic mining of regulatory elements enables programmable species-selective gene expression.
Nat Methods
2018
29632376
Highly parallel genome variant engineering with CRISPR-Cas9.
Nat Genet
2018
28911123
A systematic comparison of error correction enzymes by next-generation sequencing.
Nucleic Acids Res
2017
26689263
Engineering an allosteric transcription factor to respond to new ligands.
Nat Methods
2016
24856730
Direct mutagenesis of thousands of genomic targets using microarray-derived oligonucleotides.
ACS Synth Biol
2015
24781323
Large-scale de novo DNA synthesis: technologies and applications.
Nat Methods
2014
23924614
Composability of regulatory sequences controlling transcription and translation in Escherichia coli.
Proc Natl Acad Sci U S A
2013
24072823
Causes and effects of N-terminal codon bias in bacterial genes.
Science
2013
24136967
Probing the limits of genetic recoding in essential genes.
Science
2013
23907171
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.
Nat Biotechnol
2013
22903519
Next-generation digital information storage in DNA.
Science
2012
25077042
Gene Assembly from Chip-Synthesized Oligonucleotides.
Curr Protoc Chem Biol
2012
23651112
When it rains, it pores.
ACS Synth Biol
2012
21248753
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.
Nat Biotechnol
2011
21113165
Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips.
Nat Biotechnol
2010
18093293
TABASCO: A single molecule, base-pair resolved gene expression simulator.
BMC Bioinformatics
2007
16729053
Refactoring bacteriophage T7.
Mol Syst Biol
2005
1 - 31 of 31
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