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Author Details

Marie-Laure Yaspo
Max Planck Institute for Molecular Genetics
1992
108
48
PMIDPaper TitleJournal TitlePublished Year
36493345RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia.Blood2023
37766974Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus <i>MYNRL15</i>.iScience2023
37248468A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer.Mol Cancer2023
37373474Systemic Blood Proteome Patterns Reflect Disease Phenotypes in Neovascular Age-Related Macular Degeneration.Int J Mol Sci2023
35569281Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study.Eur J Cancer2022
35406521Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival.Cancers (Basel)2022
32703790Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas.Haematologica2021
34885128Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data.Cancers (Basel)2021
34994642Dynamic Changes of Circulating Tumor DNA Predict Clinical Outcome in Patients With Advanced Non-Small-Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.JCO Precis Oncol2021
34209696CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis.Int J Mol Sci2021
34230613Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities.Oncogene2021
32298052Mass Cytometry-A Tool for the Curious: Networking in Berlin.Cytometry A2020
31982633Support of a molecular tumour board by an evidence-based decision management system for precision oncology.Eur J Cancer2020
33115803Endocytosis-Mediated Replenishment of Amino Acids Favors Cancer Cell Proliferation and Survival in Chromophobe Renal Cell Carcinoma.Cancer Res2020
33146701Rational therapy with vigabatrin and a ketogenic diet in a patient with GAD1 deficiency.Brain2020
32853382The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL.Blood Adv2020
30673601Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes.Cell Rep2019
31735627The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability.Cancer Cell2019
31303423Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.Cancer Cell2019
31526763Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.Cancer Cell2019
315949445-Fluorouracil treatment induces characteristic T&gt;G mutations in human cancer.Nat Commun2019
28871137C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation.Leukemia2018
30024899Impact of congenital cytomegalovirus infection on transcriptomes from archived dried blood spots in relation to long-term clinical outcome.PLoS One2018
30184510Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils.Cell Rep2018
29876014Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.Oncotarget2018
29876013Combined HAT/EZH2 modulation leads to cancer-selective cell death.Oncotarget2018
30537516Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.Cancer Cell2018
29703216Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes.Genome Med2018
29785028The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia.Nat Med2018
28595192Cancer Precision Medicine: Why More Is More and DNA Is Not Enough.Public Health Genomics2017
28186126Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.Nat Commun2017
28726821The whole-genome landscape of medulloblastoma subtypes.Nature2017
26814189Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).Mol Biol Evol2016
27863251Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.Cell2016
27543603Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma.Cancer Res2016
27058758Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.Oncotarget2016
26814967Active medulloblastoma enhancers reveal subgroup-specific cellular origins.Nature2016
25485837BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence.Nat Genet2015
26546267The direction of cross affects [corrected] obesity after puberty in male but not female offspring.BMC Genomics2015
26464088Network and systems biology: essential steps in virtualising drug discovery and development.Drug Discov Today Technol2015
26621155Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'.BMC Genomics2015
26214592Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.Nat Genet2015
25875616ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells.PLoS One2015
25965575Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.Cancer Cell2015
24920826ARH-seq: identification of differential splicing in RNA-seq data.Nucleic Acids Res2014
25347188Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.PLoS One2014
25043047Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.Nature2014
25113896Influence of RNA extraction methods and library selection schemes on RNA-seq data.BMC Genomics2014
24799129The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.PLoS One2014
24825921Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.Sci Signal2014
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Collaborators

Hans-J??rg Warnatz
Max Planck Institute for Molecular Genetics
Co-authored papers 25
Vyacheslav Amstislavskiy
Max-Planck-Institute for Molecular Genetics
Co-authored papers 18
Thomas Risch
Max Planck Institute for Molecular Genetics
Co-authored papers 16
Roland Eils
Berlin Institute of Health (BIH) and Charite
Co-authored papers 10
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 9
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers 9
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 9
Jan O Korbel
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 9
Benedikt Brors
German Cancer Research Center (DKFZ)
Co-authored papers 9
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 9
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 8
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 8
Joost H A Martens
Co-authored papers 8
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 8
Hendrik G Stunnenberg
Co-authored papers 8
Marina Ryzhova
N.N. Burdenko Neurosurgical Institute
Co-authored papers 7
Jan Koster
Amsterdam University Medical Centers location AMC
Co-authored papers 7
Natalie J??ger
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
Paul Flicek
European Bioinformatics Institute
Co-authored papers 7
Chris Lawerenz
German Cancer Research Center (DKFZ)
Co-authored papers 6
Christof von Kalle
Berlin Institute of Health at Charite-Universitatsmedizin Berlin
Co-authored papers 6
Adrian M St??tz
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 6
Benjamin Raeder
Co-authored papers 6
Laura Clarke
Co-authored papers 6
Stephan Wolf
Co-authored papers 6
Ralf Herwig
Max Planck Institute for Molecular Genetics
Co-authored papers 6
Olaf Witt
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 6
Marc Zapatka
Co-authored papers 6
Simon Heath
Barcelona Institute of Science and Technology (BIST)
Co-authored papers 5
Ursula D Weber
Co-authored papers 5
Release 1.2