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Author Details

Bo Hu
Northwestern University Feinberg School of Medicine
2003
74
40
PMIDPaper TitleJournal TitlePublished Year
37580817Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis.Acta Neuropathol Commun2023
37760589Repurposing Clemastine to Target Glioblastoma Cell Stemness.Cancers (Basel)2023
36009578The Role of Non-Coding RNAs in Glioma.Biomedicines2022
35842440C698R mutation in Lrsam1 gene impairs nerve regeneration in a CMT2P mouse model.Sci Rep2022
35731869Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas.Sci Adv2022
35784465Unconventional Protein Secretion in Brain Tumors Biology: Enlightening the Mechanisms for Tumor Survival and Progression.Front Cell Dev Biol2022
34376816Author Correction: miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops.Cell Res2021
33539787PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.Mol Cell2021
33668200The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma.Cells2021
32356557Pmp22 super-enhancer deletion causes tomacula formation and conduction block in peripheral nerves.Hum Mol Genet2020
32055849LY6K promotes glioblastoma tumorigenicity via CAV-1-mediated ERK1/2 signaling enhancement.Neuro Oncol2020
32730653Demyelination in hereditary sensory neuropathy type-1C.Ann Clin Transl Neurol2020
32754274Stem cell programs in cancer initiation, progression, and therapy resistance.Theranostics2020
30654687MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy.Autophagy2019
31358019Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response.J Exp Clin Cancer Res2019
31462429SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes.Cancer Res2019
31488827CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.Nat Commun2019
31232447Targeting PDGFRα-activated glioblastoma through specific inhibition of SHP-2-mediated signaling.Neuro Oncol2019
31599491TGF-β-activated lncRNA LINC00115 is a critical regulator of glioma stem-like cell tumorigenicity.EMBO Rep2019
31313076Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J.Mol Neurobiol2019
31311601Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response.J Orthop Surg Res2019
30953555Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response.J Exp Clin Cancer Res2019
29518270Myelin abnormality in Charcot-Marie-Tooth type 4J recapitulates features of acquired demyelination.Ann Neurol2018
29927689Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma.Epigenetics2018
30311559Autophagy and Hallmarks of Cancer.Crit Rev Oncog2018
29386185TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.Cancer Res2018
28888069A novel missense mutation in AIFM1 results in axonal polyneuropathy and misassembly of OXPHOS complexes.Eur J Neurol2017
29232556MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.Cancer Cell2017
29129908TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma.Nat Commun2017
29021135Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.Cancer Res2017
28716909Internalized CD44s splice isoform attenuates EGFR degradation by targeting Rab7A.Proc Natl Acad Sci U S A2017
26757811A simple, low-cost staining method for rapid-throughput analysis of tumor spheroids.Biotechniques2016
27615052A novel missense mutation of CMT2P alters transcription machinery.Ann Neurol2016
27698350A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.Nat Commun2016
27583434Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP.PLoS Genet2016
27041571SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.Oncogene2016
25468898Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.Neuro Oncol2015
26251826Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells.Genom Data2015
26317392Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets.PLoS Comput Biol2015
25926456Reactivation of Lysosomal Ca2+ Efflux Rescues Abnormal Lysosomal Storage in FIG4-Deficient Cells.J Neurosci2015
23728337EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180.Oncogene2014
25061874EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.J Clin Invest2014
24339129Abnormal junctions and permeability of myelin in PMP22-deficient nerves.Ann Neurol2014
23325792YM-155 potentiates the effect of ABT-737 in malignant human glioma cells via survivin and Mcl-1 downregulation in an EGFR-dependent context.Mol Cancer Ther2013
24206916Noncoding RNAs in cancer and cancer stem cells.Chin J Cancer2013
23695168Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas.Clin Cancer Res2013
23650391Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.Proc Natl Acad Sci U S A2013
23383216Bmi-1 promotes glioma angiogenesis by activating NF-κB signaling.PLoS One2013
23204229Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype.Cancer Res2013
23247627miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops.Cell Res2013
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Collaborators

Shi-Yuan Cheng
Northwestern University Feinberg School of Medicine
Co-authored papers 64
Ryo Nishikawa
Saitama Medical University International Medical Center
Co-authored papers 12
Michael J Jarzynka
Division of Pharmaceutical Sciences, Duquesne University School of Pharmacy
Co-authored papers 9
Ping Guo
Steadman Philippon Research Institute, Center for Regenerative Sports Medicine
Co-authored papers 9
Webster K Cavenee
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 6
Craig Horbinski
Co-authored papers 6
Charles D James
Co-authored papers 6
Yorihisa Imanishi
International University of Health and Welfare, Narita Hospital
Co-authored papers 5
Songjian Lu
Co-authored papers 5
Motoo Nagane
Kyorin University Faculty of Medicine
Co-authored papers 5
Xinghua Lu
Co-authored papers 5
Jann N Sarkaria
Co-authored papers 5
Frank B Furnari
University of California San Diego
Co-authored papers 4
Ifat Bar-Joseph
The Center for Cancer Research-Sheba Medical Center
Co-authored papers 4
Erik P Sulman
NYU Grossman School of Medicine
Co-authored papers 4
Takanori Hirose
Hyogo Cancer Center
Co-authored papers 3
Cameron Brennan
Co-authored papers 3
Roger Stupp
Northwestern University
Co-authored papers 2
Panayiotis V Benos
University of Florida
Co-authored papers 2
Jianfeng Li
Mitchell Cancer Institute, University of South Alabama
Co-authored papers 2
Soumya Luthra
Co-authored papers 2
Darell D Bigner
Co-authored papers 2
Robert W Sobol
University of South Alabama
Co-authored papers 2
H-J Su Huang
Regeneron Pharmaceuticals Inc.
Co-authored papers 2
Uma R Chandran
Co-authored papers 2
Roger E McLendon
Co-authored papers 2
Stephen T Keir
Co-authored papers 1
Mark H Ellisman
National Center for Microscopy and Imaging Research, University of California
Co-authored papers 1
Lin Wang
Co-authored papers 1
Oliver B??gler
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Release 1.2