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Author Details
Full Name
Linzhao Cheng
Affiliation
Johns Hopkins University School of Medicine
ORCID
Career Start Year
1989
Papers
145
H Index
56
Expertise
CM4AI Collaborator
Prashant Mali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36436185
PEAR1 is a potential regulator of early hematopoiesis of human pluripotent stem cells.
J Cell Physiol
2023
34779029
Erythropoietic properties of human induced pluripotent stem cells-derived red blood cells in immunodeficient mice.
Am J Hematol
2022
35399545
In memory of Hal E. Broxmeyer, a pluripotent scientist, pioneer, and mentor.
Blood Sci
2022
33094331
Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole-genome and RNA sequencing.
Blood
2021
33829634
Gene and protein expression in human megakaryocytes derived from induced pluripotent stem cells.
J Thromb Haemost
2021
33796838
<i>HIF2A</i> gain-of-function mutation modulates the stiffness of smooth muscle cells and compromises vascular mechanics.
iScience
2021
33489014
Highly efficient magnetic labelling allows MRI tracking of the homing of stem cell-derived extracellular vesicles following systemic delivery.
J Extracell Vesicles
2021
33484967
BMI1 enables extensive expansion of functional erythroblasts from human peripheral blood mononuclear cells.
Mol Ther
2021
31197070
Sequential cellular niches control the generation of enucleated erythrocytes from human pluripotent stem cells.
Haematologica
2020
32011235
Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors.
Elife
2020
32916633
Generation and characterization of a novel human iPSC line from a resilient Alzheimer's disease patient.
Stem Cell Res
2020
32845994
Human Forebrain Organoids from Induced Pluripotent Stem Cells: A Novel Approach to Model Repair of Ionizing Radiation-Induced DNA Damage in Human Neurons.
Radiat Res
2020
32442913
Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program.
Stem Cell Res
2020
32511247
iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu.
PLoS One
2020
30391800
Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior.
Biomaterials
2019
31303172
The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model.
Fluids Barriers CNS
2019
30811771
Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells.
Stem Cells
2019
29164808
A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease.
Stem Cells Transl Med
2018
29849122
Heterozygous IDH1<sup>R132H/WT</sup> created by "single base editing" inhibits human astroglial cell growth by downregulating YAP.
Oncogene
2018
29554589
Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system.
Stem Cell Res
2018
29101237
Human <i>NOTCH4</i> is a key target of RUNX1 in megakaryocytic differentiation.
Blood
2018
27913985
Erratum to: Questions about NgAgo.
Protein Cell
2017
28107356
Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis.
PLoS One
2017
28395806
Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene.
Stem Cell Res
2017
28441409
A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model.
PLoS One
2017
27037073
A Method for Genome Editing in Human Pluripotent Stem Cells.
Cold Spring Harb Protoc
2016
26395760
Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated From Hemogenic Endothelial Cells in Human Pluripotent Stem Cells.
J Cell Physiol
2016
27879207
Integration-free erythroblast-derived human induced pluripotent stem cells (iPSCs) from an individual with Ataxia-Telangiectasia (A-T).
Stem Cell Res
2016
27848216
Questions about NgAgo.
Protein Cell
2016
27596957
Robust reprogramming of Ataxia-Telangiectasia patient and carrier erythroid cells to induced pluripotent stem cells.
Stem Cell Res
2016
27416908
A germline ERBB3 variant is a candidate for predisposition to erythroid MDS/erythroleukemia.
Leukemia
2016
27037079
Genome Editing in Human Pluripotent Stem Cells.
Cold Spring Harb Protoc
2016
25418680
Efficient and allele-specific genome editing of disease loci in human iPSCs.
Mol Ther
2015
25713465
Efficient generation of megakaryocytes from human induced pluripotent stem cells using food and drug administration-approved pharmacological reagents.
Stem Cells Transl Med
2015
25702619
Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation.
Stem Cells
2015
25635918
Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors.
PLoS One
2015
25742692
A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach.
Stem Cells Transl Med
2015
23765875
Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis.
Stem Cells
2014
25254336
Whole-genome sequencing identifies genetic variances in culture-expanded human mesenchymal stem cells.
Stem Cell Reports
2014
24996165
Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs.
Cell Stem Cell
2014
25114263
Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects.
Blood
2014
25132547
Synaptic dysregulation in a human iPS cell model of mental disorders.
Nature
2014
24361925
Concise review: stem cell-based approaches to red blood cell production for transfusion.
Stem Cells Transl Med
2014
24357517
Early frameshift mutation in PIGA identified in a large XLID family without neonatal lethality.
Hum Mutat
2014
24132657
Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013.
Ann Biomed Eng
2014
24105986
Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells.
Stem Cells
2014
24002691
Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors.
Mol Ther
2014
23372166
RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells.
Blood
2013
24839581
Induced pluripotent stem cell-derived mesenchymal stem cell seeding on biofunctionalized calcium phosphate cements.
Bone Res
2013
24511466
A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells.
Stem Cell Reports
2013
1 - 50 of 145
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Sharon Gerecht
Duke University, Johns Hopkins University
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Peter J Donovan
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5
Yu Alex Zhang
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4
Jonathan Yen
St. Jude Children's Research Hospital
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4
Lisa R Yanek
Co-authored papers
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Margaret A Taub
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Yoon-Young Jang
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