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Author Details

Solomon F Ofori-Acquah
Pittsburgh Heart Lung and Blood Vascular Medicine Institute, University of Pittsburgh
1998
78
25
PMIDPaper TitleJournal TitlePublished Year
36979670Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice.Biomedicines2023
37481464Access to essential therapy for sickle cell disease in Africa: Experience from a national program in Ghana.Semin Hematol2023
37215630White-matter abnormalities and cognitive dysfunction are linked to astrocyte activation in sickle mice.PNAS Nexus2023
36173295The BLOODSAFE program: Building the future of access to safe blood in Sub-Saharan Africa.Transfusion2022
35843392Hydroxyurea Decouples Persistent F-Cell Elevation and Induction of γ-Globin.Exp Hematol2022
35620281Nrf2 Activation With CDDO-Methyl Promotes Beneficial and Deleterious Clinical Effects in Transgenic Mice With Sickle Cell Anemia.Front Pharmacol2022
35513726Polygenic risk scores for CARDINAL study.Nat Genet2022
33267657Xanthine Oxidase Drives Hemolysis and Vascular Malfunction in Sickle Cell Disease.Arterioscler Thromb Vasc Biol2021
34301659Sickle Cell Disease Genomics of Africa (SickleGenAfrica) Network: ethical framework and initial qualitative findings from community engagement in Ghana, Nigeria and Tanzania.BMJ Open2021
32151553Nrf2 deficiency in mice attenuates erythropoietic stress-related macrophage hypercellularity.Exp Hematol2020
32043112Hemopexin deficiency promotes acute kidney injury in sickle cell disease.Blood2020
32004491SickleInAfrica.Lancet Haematol2020
33173534Editorial: The Genetic and Environmental Basis for Diseases in Understudied Populations.Front Genet2020
32973791Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice.Front Immunol2020
32971049The SickleGenAfrica Network.Lancet Glob Health2020
32362160Sickle cell disease as a vascular disorder.Expert Rev Hematol2020
30809798P-selectin plays a role in haem-induced acute lung injury in sickle mice.Br J Haematol2019
31821458Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice.Blood Adv2019
30159633Sleep phenotype in the Townes mouse model of sickle cell disease.Sleep Breath2019
31389006Cardiac expression of HMOX1 and PGF in sickle cell mice and haem-treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2).Br J Haematol2019
31408727Free heme regulates placenta growth factor through NRF2-antioxidant response signaling.Free Radic Biol Med2019
31428225Effects of Individualized Treadmill Endurance Training on Oxidative Stress in Skeletal Muscles of Transgenic Sickle Mice.Oxid Med Cell Longev2019
28624257Moderate exercise training decreases inflammation in transgenic sickle cell mice.Blood Cells Mol Dis2018
29923176Augmented NRF2 activation protects adult sickle mice from lethal acute chest syndrome.Br J Haematol2018
30533277Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease.Nat Biomed Eng2018
29300776Prevalence of relative systemic hypertension in adults with sickle cell disease in Ghana.PLoS One2018
27616638Sustained enhancement of OCTN1 transporter expression in association with hydroxyurea induced γ-globin expression in erythroid progenitors.Exp Hematol2017
28851791Organ damage in sickle cell disease study (ORDISS): protocol for a longitudinal cohort study based in Ghana.BMJ Open2017
28635598Sickle cell disease: tipping the balance of genomic research to catalyse discoveries in Africa.Lancet2017
26226206Inflammatory targets of therapy in sickle cell disease.Transl Res2016
27835777Inflammatory and oxidative stress phenotypes in transgenic sickle cell mice.Blood Cells Mol Dis2016
27233995Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.Am J Physiol Lung Cell Mol Physiol2016
27354937Proceedings of a Sickle Cell Disease Ontology workshop - Towards the first comprehensive ontology for Sickle Cell Disease.Appl Transl Genom2016
27494522Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia.PLoS One2016
27158670Nonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice.JCI Insight2016
27026725Original Research: Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model.Exp Biol Med (Maywood)2016
25193810Using formative research to develop a counselor training program for newborn screening in Ghana.J Genet Couns2015
25962948Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients.Cardiovasc J Afr2015
25957113Microarchitectural and mechanical characterization of the sickle bone.J Mech Behav Biomed Mater2015
24948725Research capacity. Enabling the genomic revolution in Africa.Science2014
25255861Enhanced down-regulation of ALCAM/CD166 in African-American Breast Cancer.BMC Cancer2014
24842894High protein diet attenuates histopathologic organ damage and vascular leakage in transgenic murine model of sickle cell anemia.Exp Biol Med (Maywood)2014
24926069Erythroid DAMPs drive inflammation in SCD.Blood2014
23802701Association between plasma free haem and incidence of vaso-occlusive episodes and acute chest syndrome in children with sickle cell disease.Br J Haematol2013
25143960Sickle cell disease: new opportunities and challenges in Africa.ScientificWorldJournal2013
24084741Extracellular hemin crisis triggers acute chest syndrome in sickle mice.J Clin Invest2013
21790627Alloimmunization to transfused HOD red blood cells is not increased in mice with sickle cell disease.Transfusion2012
22966170Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease.Blood2012
22941204Cloning of the human activated leukocyte cell adhesion molecule promoter and identification of its tissue-independent transcriptional activation by Sp1.Cell Mol Biol Lett2012
22957221Sickle cell disease: genetics, cellular and molecular mechanisms, and therapies.Anemia2012
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Collaborators

Kwaku Ohene-Frempong
Sickle Cell Foundation of Ghana
Co-authored papers 8
Nicola Mulder
University of Cape Town
Co-authored papers 6
Ambroise Wonkam
University of Cape Town
Co-authored papers 6
Obiageli E Nnodu
University of Abuja (CESRTA) Federal Capital Territory (FCT)
Co-authored papers 4
Marsha Treadwell
University of California San Francisco
Co-authored papers 4
Kofi A Anie
London North West University Healthcare NHS Trust, Imperial College London
Co-authored papers 4
Mayowa Owolabi
Center for Genomic and Precision Medicine, University of Ibadan
Co-authored papers 3
Neil A Hanchard
Baylor College of Medicine.
Co-authored papers 3
Bamidele O Tayo
Loyola University Medical Center.
Co-authored papers 3
Mark T Gladwin
University of Maryland School of Medicine
Co-authored papers 3
Jacqueline M Hibbert
Morehouse School of Medicine
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Clement Adebamowo
Institute for Human Virology
Co-authored papers 2
Adebowale Adeyemo
Center for Research on Genomics and Global Health, National Institutes of Health
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Raphael Z Sangeda
Muhimbili University of Health and Allied Sciences
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Thomas R Ziegler
Emory University School of Medicine
Co-authored papers 2
Muntaser Ibrahim
Institute of Endemic Diseases, University of Khartoum
Co-authored papers 2
Victoria Nembaware
University of Cape Town
Co-authored papers 2
Charmaine D M Royal
Duke University
Co-authored papers 2
James C Zimring
University of Virginia
Co-authored papers 1
Braxton D Mitchell
Co-authored papers 1
Damian Nirenberg
Baylor College of Medicine
Co-authored papers 1
Adekunle Adekile
Kuwait University.
Co-authored papers 1
Mehdi Nouraie
Co-authored papers 1
Catherine Chunda-Liyoka
University Teaching Hospitals-Children's Hospital
Co-authored papers 1
Claudia S Cohn
University of Minnesota
Co-authored papers 1
Rulan S Parekh
Co-authored papers 1
Oyedunni Arulogun
University of Ibadan
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Martin R Pollak
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Mark S Guyer
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Release 1.2