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Author Details
Full Name
Debyani Chakravarty
Affiliation
Memorial Sloan Kettering Cancer Center
ORCID
Career Start Year
2002
Papers
53
H Index
30
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37849038
Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer.
Cancer Discov
2024
37651310
Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications.
Cancer Discov
2023
38084089
Precision Oncology: 2023 in Review.
Cancer Discov
2023
37898613
Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing.
Nat Commun
2023
37890492
Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers.
Cancer Cell
2023
35165384
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Nat Biotechnol
2022
35440569
AKT mutant allele-specific activation dictates pharmacologic sensitivities.
Nat Commun
2022
35796744
Response to Mehta et al.
Genet Med
2022
36458431
Precision Oncology: 2022 in Review.
Cancer Discov
2022
36357680
Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer.
Nat Med
2022
36063163
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).
Genet Med
2022
36228155
Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention.
Clin Cancer Res
2022
36048199
Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort.
Cancer Discov
2022
35101336
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).
Genet Med
2022
35066956
Computational methods and translational applications for targeted next-generation sequencing platforms.
Genes Chromosomes Cancer
2022
35175857
Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion.
J Clin Oncol
2022
34059130
Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients.
Genome Med
2021
33625877
OncoTree: A Cancer Classification System for Precision Oncology.
JCO Clin Cancer Inform
2021
33762738
Clinical cancer genomic profiling.
Nat Rev Genet
2021
35072136
GA4GH: International policies and standards for data sharing across genomic research and healthcare.
Cell Genom
2021
34133209
Therapeutic Implications of Germline Testing in Patients With Advanced Cancers.
J Clin Oncol
2021
34351646
Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.
Cancer
2021
32193223
The Evolutionary Origins of Recurrent Pancreatic Cancer.
Cancer Discov
2020
32644817
Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices.
JCO Clin Cancer Inform
2020
32721511
RAS/MAPK Pathway Driver Alterations Are Significantly Associated With Oncogenic KIT Mutations in Germ-cell Tumors.
Urology
2020
32246132
A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.
Nat Genet
2020
31152158
Publisher Correction: The long tail of oncogenic drivers in prostate cancer.
Nat Genet
2019
32914018
Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology.
JCO Precis Oncol
2019
32914011
Comprehensive Genomic Analysis of Metastatic Non-Clear-Cell Renal Cell Carcinoma to Identify Therapeutic Targets.
JCO Precis Oncol
2019
31175097
Clinical Genomic Sequencing of Pediatric and Adult Osteosarcoma Reveals Distinct Molecular Subsets with Potentially Targetable Alterations.
Clin Cancer Res
2019
29247016
Accelerating Discovery of Functional Mutant Alleles in Cancer.
Cancer Discov
2018
30137196
A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
Ann Oncol
2018
30311369
Integrating somatic variant data and biomarkers for germline variant classification in cancer predisposition genes.
Hum Mutat
2018
29610475
The long tail of oncogenic drivers in prostate cancer.
Nat Genet
2018
29683790
Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas.
J Clin Oncol
2018
29625050
Oncogenic Signaling Pathways in The Cancer Genome Atlas.
Cell
2018
27442865
The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform.
JAMA Oncol
2017
28336552
Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.
Cancer Discov
2017
28481359
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
Nat Med
2017
28472509
Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma.
Neuro Oncol
2017
29045506
Clinical and molecular characterization of patients with cancer of unknown primary in the modern era.
Ann Oncol
2017
28777785
Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
Nat Med
2017
28911072
Oncologist use and perception of large panel next-generation tumor sequencing.
Ann Oncol
2017
28831081
EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines.
Sci Rep
2017
28825054
Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.
JCO Precis Oncol
2017
28890946
OncoKB: A Precision Oncology Knowledge Base.
JCO Precis Oncol
2017
27807832
Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression.
Methods Mol Biol
2017
24120142
The somatic genomic landscape of glioblastoma.
Cell
2013
22323597
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response.
Proc Natl Acad Sci U S A
2012
22105174
Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation.
J Clin Invest
2011
1 - 50 of 53
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Barry S Taylor
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Hongxin Zhang
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Wassim Abida
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Alexander Drilon
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Howard I Scher
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Alex H Wagner
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Obi L Griffith
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Beth A Pitel
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Ang??lica Ochoa-Avil??s
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