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Author Details

Ana Maria Cuervo
Albert Einstein College of Medicine
1990
265
114
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38039131NGLY1 mutations cause protein aggregation in human neurons.Cell Rep2023
38060380Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy.Cell Rep2023
37831778A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion.Sci Adv2023
34498278Extending human healthspan and longevity: a symposium report.Ann N Y Acad Sci2022
35740279Methamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV Neuropathogenesis.Biomedicines2022
35363568Protective role of chaperone-mediated autophagy against atherosclerosis.Proc Natl Acad Sci U S A2022
35787098Chaperone-mediated autophagy protects against atherosclerosis.Autophagy2022
35452608Quality Control: Maintaining molecular order and preventing cellular chaos.Mol Cell2022
35482760Misfolded GBA/β-glucocerebrosidase impairs ER-quality control by chaperone-mediated autophagy in Parkinson disease.Autophagy2022
35413950Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.Nat Commun2022
35864098Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.Nat Commun2022
36383673Chaperone-mediated autophagy regulates adipocyte differentiation.Sci Adv2022
36087066The lysosomal proteome of senescent cells contributes to the senescence secretome.Aging Cell2022
36116133Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion.Aging Cell2022
35131870Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity.Cancer Res2022
35120120Correction: Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.PLoS Biol2022
35138901Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.Sci Adv2022
35167431Circadian remodeling of the proteome by chaperone-mediated autophagy.Autophagy2022
34895031Immunosurveillance, interferon, and autophagic networking in cancer: the PRKCI-ULK2 paradigm.Autophagy2022
35134347The different autophagy degradation pathways and neurodegeneration.Neuron2022
33442062Chaperone-mediated autophagy sustains haematopoietic stem-cell function.Nature2021
36846190Molecular Damage in Aging.Nat Aging2021
33854069Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.Nat Commun2021
33891876Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.Cell2021
34876687Reciprocal regulation of chaperone-mediated autophagy and the circadian clock.Nat Cell Biol2021
34739309TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy.Sci Adv2021
34463901Einstein-Nathan Shock Center: translating the hallmarks of aging to extend human health span.Geroscience2021
34459017Autophagy in major human diseases.EMBO J2021
34571832HIV Increases the Inhibitory Impact of Morphine and Antiretrovirals on Autophagy in Primary Human Macrophages: Contributions to Neuropathogenesis.Cells2021
34563704Autophagy and the hallmarks of aging.Ageing Res Rev2021
34560002PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.Mol Cell2021
34315875Gαq activation modulates autophagy by promoting mTORC1 signaling.Nat Commun2021
33947846MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells.Nat Commun2021
34110247Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis.Autophagy2021
34225914Assessment of mammalian endosomal microautophagy.Methods Cell Biol2021
30982401The negative effect of lipid challenge on autophagy inhibits T cell responses.Autophagy2020
31906970Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.Mol Neurodegener2020
31699565Pros and Cons of Chaperone-Mediated Autophagy in Cancer Biology.Trends Endocrinol Metab2020
33378272ARDD 2020: from aging mechanisms to interventions.Aging (Albany NY)2020
33092174In Vivo Remodeling of Altered Autophagy-Lysosomal Pathway by a Phosphopeptide in Lupus.Cells2020
32714562Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome.NPJ Aging Mech Dis2020
32765937Geroscience in the Age of COVID-19.Aging Dis2020
32703867Beth Cindy Levine (1960-2020).Science2020
32589943PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.Cancer Cell2020
32526847HIV Nef and Antiretroviral Therapy Have an Inhibitory Effect on Autophagy in Human Astrocytes that May Contribute to HIV-Associated Neurocognitive Disorders.Cells2020
32413333Disulfiram Treatment Normalizes Body Weight in Obese Mice.Cell Metab2020
32349535Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis.Arterioscler Thromb Vasc Biol2020
30382371Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.Acta Neuropathol2019
31707363Age-associated changes in human CD4<sup>+</sup> T cells point to mitochondrial dysfunction consequent to impaired autophagy.Aging (Albany NY)2019
31548426Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy.Proc Natl Acad Sci U S A2019
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Collaborators

Susmita Kaushik
Albert Einstein College of Medicine
Co-authored papers 54
Antonio Diaz
Albert Einstein College of Medicine, USA Institute for Aging Studies
Co-authored papers 28
Inmaculada Tasset
Albert Einstein College of Medicine
Co-authored papers 16
Laura Santambrogio
Weill Cornell School of Medicine
Co-authored papers 15
David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 11
Jose Antonio Rodriguez
University of the Basque Country (UPV/EHU)
Co-authored papers 10
Mathieu Bourdenx
University College London, UK Dementia Research Institute
Co-authored papers 10
Evripidis Gavathiotis
Albert Einstein College of Medicine
Co-authored papers 8
Cristina C Clement
Englander Institute for Precision Medicine
Co-authored papers 7
Gregory J Krause
Albert Einstein College of Medicine
Co-authored papers 7
Yves R Juste
Albert Einstein College of Medicine
Co-authored papers 7
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 6
Zvulun Elazar
Weizmann Institute of Science
Co-authored papers 6
Nir Barzilai
Co-authored papers 6
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 5
Jorge Moscat
Co-authored papers 5
Steven Finkbeiner
J. David Gladstone Institutes
Co-authored papers 5
Bruce L Miller
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 5
Jayanta Debnath
University of California San Francisco
Co-authored papers 5
Maria T Diaz-Meco
Co-authored papers 5
Juan Fueyo
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 5
Luigi Ferrucci
National Institute on Aging, National Institutes of Health
Co-authored papers 4
Ivan Dikic
Institute of Biochemistry II, Goethe University Frankfurt
Co-authored papers 4
Malene Hansen
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
William T Dauer
Peter O'Donnell Jr. Brain Institute
Co-authored papers 3
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 3
Jose Javier Bravo-Cordero
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Nevan J Krogan (CM4AI)
University of California San Francisco
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Release 1.2