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Author Details

Danish Saleheen
2002
162
72
PMIDPaper TitleJournal TitlePublished Year
37034649Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.medRxiv2023
37291107South Asian medical cohorts reveal strong founder effects and high rates of homozygosity.Nat Commun2023
35915156Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.Nat Med2022
35654975A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.Nat Genet2022
35393509Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.Commun Biol2022
35513483Author Correction: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.Commun Biol2022
35381001Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.PLoS Genetics2022
35551307Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.Nat Genet2022
34503513Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.BMC Med2021
33630758Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.J Clin Invest2021
34108472Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.Nat Commun2021
33727701Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2021
33822779Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.PLoS Genet2021
30617275Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.Mol Psychiatry2020
31929188The promise and reality of therapeutic discovery from large cohorts.J Clin Invest2020
31707836Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis.Circulation2020
32862661Heterozygous <i>ABCG5</i> Gene Deficiency and Risk of Coronary Artery Disease.Circ Genom Precis Med2020
33230300Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2020
32841307Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program.PLoS One2020
30887811An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.J Proteome Res2019
30389748DNA Sequence Variation in <i>ACVR1C</i> Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.Diabetes2019
31285632Genome-wide association study of peripheral artery disease in the Million Veteran Program.Nat Med2019
30865486CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease.Circulation2019
31160809Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nat Genet2019
31118516Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.Nature2019
31337231Association of <i>APOL1</i> Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program.Circulation2019
29273807Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nat Genet2018
28982690Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.Circulation2018
29926099Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.JAMA Cardiol2018
30383853Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.PLoS One2018
30275531Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.Nat Genet2018
29531354Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.Nat Genet2018
29549330Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nat Genet2018
29549329Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nat Genet2018
29691411Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.Nat Commun2018
29632382Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.Nat Genet2018
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
28209224Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.J Am Coll Cardiol2017
28506971Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.Circ Res2017
28951623Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Nat Genet2017
28461624Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions.Circulation2017
28385496ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.J Am Coll Cardiol2017
28636844Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.N Engl J Med2017
28898252Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.PLoS Med2017
28942964Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport.Am J Hum Genet2017
28450349Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.Circulation2017
28530674Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.Nat Genet2017
28408323Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis.Lancet Diabetes and Endocrinology,The2017
28838919Lipoprotein(a) and Risk of Myocardial Infarction and Death in Chronic Kidney Disease: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort).Arterioscler Thromb Vasc Biol2017
28406212Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.Nature2017
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Pat Macpherson Centre for Pharmacogenomics and Pharmacogenetics, University of Dundee
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Stanford University School of Medicine
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