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Author Details

David J Gonzalez
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
2008
85
32
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36865326Proteome allocation is linked to transcriptional regulation through a modularized transcriptome.bioRxiv2023
37609270A bacterial sialidase mediates early life colonization by a pioneering gut commensal.bioRxiv2023
37600600Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease.Brain Behav Immun Health2023
36457235Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia.Arthritis Rheumatol2023
34741130Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia.Mol Psychiatry2022
35378331The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.Cell Mol Gastroenterol Hepatol2022
35567293Case Series of Successful Intravenous Immunoglobulin (IVIG) Treatment in 4 Pregnant Patients with Severe COVID-19-Induced Hypoxia.Am J Case Rep2022
36503356Stool multi-omics for the study of host-microbe interactions in inflammatory bowel disease.Gut Microbes2022
36558759A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using <i>Leishmania donovani</i>.Pathogens2022
35999575Location-specific signatures of Crohn's disease at a multi-omics scale.Microbiome2022
36166510Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition.Sci Signal2022
35257745Phosphoproteomic analysis of thrombin- and p38 MAPK-regulated signaling networks in endothelial cells.J Biol Chem2022
35017099Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression.Mol Cell Proteomics2022
35087228Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity.Nat Microbiol2022
34465145The α-Arrestin ARRDC3 Is an Emerging Multifunctional Adaptor Protein in Cancer.Antioxid Redox Signal2022
34282211A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition.Sci Rep2021
33767426The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway.Nat Immunol2021
33489941A Hetero-Multimeric Chitinase-Containing <i>Plasmodium falciparum</i> and <i>Plasmodium gallinaceum</i> Ookinete-Secreted Protein Complex Involved in Mosquito Midgut Invasion.Front Cell Infect Microbiol2021
33850054mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.Sci Signal2021
33621216Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival.JCI Insight2021
33811140CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly.Proc Natl Acad Sci U S A2021
33801801Urinary Exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury.Int J Mol Sci2021
33748723Dissociation of DNA damage sensing by endoglycosidase HPSE.iScience2021
34843601A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.PLoS Pathog2021
34516752Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption.Sci Signal2021
34721327The S Protein of Group B <i>Streptococcus</i> Is a Critical Virulence Determinant That Impacts the Cell Surface Virulome.Front Microbiol2021
34592883Unique virulence role of post-translocational chaperone PrsA in shaping <i>Streptococcus pyogenes</i> secretome.Virulence2021
31532487AssessORF: combining evolutionary conservation and proteomics to assess prokaryotic gene predictions.Bioinformatics2020
31992612Organ-level protein networks as a reference for the host effects of the microbiome.Genome Res2020
32071217Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function.Proc Natl Acad Sci U S A2020
31981578Identification of a Human Skin Commensal Bacterium that Selectively Kills Cutibacterium acnes.J Invest Dermatol2020
32888495Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures.Cell2020
32884027Development of muscle atrophy and loss of function in a Gulf-War illness model: underlying mechanisms.Sci Rep2020
32873645Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers.Proc Natl Acad Sci U S A2020
33024048Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic.mSystems2020
32843537Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B <i>Streptococcus</i>.mSystems2020
32433643Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways.PLoS Negl Trop Dis2020
32200644Fermentable fibers induce rapid macro- and micronutrient depletion in Toll-like receptor 5-deficient mice.Am J Physiol Gastrointest Liver Physiol2020
32559205Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer.PLoS One2020
32397563Exposure of <i>Mycobacterium abscessus</i> to Environmental Stress and Clinically Used Antibiotics Reveals Common Proteome Response among Pathogenic Mycobacteria.Microorganisms2020
30657448Essential metabolism for a minimal cell.Elife2019
31749666Quantitative analysis of <i>Mycobacterium avium</i> subsp<i>. hominissuis</i> proteome in response to antibiotics and during exposure to different environmental conditions.Clin Proteomics2019
31801066Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion.Cell Rep2019
31184899Multiantigenic Nanotoxoids for Antivirulence Vaccination against Antibiotic-Resistant Gram-Negative Bacteria.Nano Lett2019
31198645<i>PTMphinder</i>: an R package for PTM site localization and motif extraction from proteomic datasets.PeerJ2019
31507572Functional and Proteomic Analysis of <i>Streptococcus pyogenes</i> Virulence Upon Loss of Its Native Cas9 Nuclease.Front Microbiol2019
30801026Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn's Disease.mSystems2019
31110287EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells.Nat Cell Biol2019
30760325Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome.Microbiome2019
29451913Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis.PLoS One2018
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Collaborators

Co-authored papers 24
The Scripps Research Institute
Co-authored papers 22
university of california san diego School of Medicine
Co-authored papers 22
University of California
Co-authored papers 7
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 6
University of California
Co-authored papers 6
University of California
Co-authored papers 5
Feinberg School of Medicine Northwestern University
Co-authored papers 4
University of California
Co-authored papers 4
Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University
Co-authored papers 4
University of California
Co-authored papers 3
University of California San Diego, USA VA San Diego Healthcare System
Co-authored papers 3
University of California San Diego
Co-authored papers 3
University of California San Diego
Co-authored papers 2
University of California
Co-authored papers 2
Sandler Center for Drug Discovery, University of California San Francisco
Co-authored papers 2
University of California
Co-authored papers 2
University of California
Co-authored papers 2
Center for Microbiome Innovation, University of California San Diego
Co-authored papers 2
University of Alabama at Birmingham, USA O'Neal Comprehensive Cancer Center
Co-authored papers 2
Co-authored papers 2
University of California, USA Institute for Genomic Medicine
Co-authored papers 2
Co-authored papers 2
Department of Pediatrics and Rady's Children's Hospital, University of California
Co-authored papers 2
University of California
Co-authored papers 2
University of Georgia
Co-authored papers 2
Gladstone Institutes
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of California
Co-authored papers 2
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1