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Author Details

Niels Grarup
2001
260
71
PMIDPaper TitleJournal TitlePublished Year
36918541Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.Nat Commun2023
38016806Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation.2023
37653071Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake.2023
37729024Meal sugar-protein balance determines postprandial FGF21 response in humans.2023
37903942GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal.2023
37794016European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.Nat Commun2023
37883362Correction: Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography.PLoS One2023
37627608Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents.2023
37034649Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.medRxiv2023
37090505Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists.2023
37208954An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents.2023
36649380A novel splice-affecting variant with large population impact on diabetes in Greenland.2023
37398003Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.medRxiv2023
37008541Identification of pathogenic variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment.2023
36809463Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity.2023
36944026The effect of diabetes and the diabetogenic p.Arg684ter variant on kidney function in Inuit in Greenland.2023
36693378Loci for insulin processing and secretion provide insight into type 2 diabetes risk.Am J Hum Genet2023
37303008Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition.2023
37235780Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes.2023
34978666Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis.Eur J Epidemiol2022
36314488Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study.Journal of the American Heart Association2022
35382499The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism.Journal of the Endocrine Society2022
35381269Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.J Allergy Clin Immunol2022
35551307Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.Nat Genet2022
36267056An missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention.Human Genetics and Genomics Advances2022
3640017114-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes.Diabetes Res Clin Pract2022
36050321Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.Nat Commun2022
36467723Association of general health and lifestyle factors with the salivary microbiota - Lessons learned from the ADDITION-PRO cohort.Frontiers in Cellular and Infection Microbiology2022
34862199Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.Diabetes2022
34914943Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.Gastroenterology2022
34753975DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine.Scientific Reports2021
33912980Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers.Diabetologia2021
34108472Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.Nat Commun2021
34048700Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.Cell2021
34048505Genetic markers of abdominal obesity and weight loss after gastric bypass surgery.PLoS ONE2021
34265066The Effect of Melatonin on Incretin Hormones: Results From Experimental and Randomized Clinical Studies.Journal of Clinical Endocrinology and Metabolism2021
33727701Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2021
34040033Explaining deep neural networks for knowledge discovery in electrocardiogram analysis.Scientific Reports2021
33876560FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.J Thromb Haemost2021
34254976Abdominal and gluteofemoral fat depots show opposing associations with postprandial lipemia.American Journal of Clinical Nutrition2021
34143812Insulin resistance genetic risk score and burden of coronary artery disease in patients referred for coronary angiography.PLoS One2021
33711251The genetic history of Greenlandic-European contact.Current Biology2021
33220095Acute metabolic effects of melatonin-A randomized crossover study in healthy young men.Journal of Pineal Research2021
32944759Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.Journal of Clinical Endocrinology and Metabolism2021
33407418Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test.BMC Medical Genomics2021
34662357Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations.PLoS ONE2021
34760890Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes.Frontiers in Cell and Developmental Biology2021
32888493Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.Cell2020
32291466Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study.Diabetologia2020
32273574Estimating narrow-sense heritability using family data from admixed populations.Heredity2020
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Stanford University School of Medicine
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Erasmus University Medical Center
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King's College London
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