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Author Details

Jeongwu Lee
Lerner Research Institute, Cleveland Clinic
2001
62
42
PMIDPaper TitleJournal TitlePublished Year
36972629Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.Neoplasia2023
37788099The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling.JCI Insight2023
37451272Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling.Cancer Cell2023
36400883Tissue factor links inflammation, thrombosis, and senescence in COVID-19.Sci Rep2022
33479772Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma.Brain2021
32532977ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages.Nat Commun2020
33149237Correction: Secretome analysis of patient-derived GBM tumorspheres identifies midkine as a potent therapeutic target.Exp Mol Med2020
32847614Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma.Genome Biol2020
30899443Statins affect human glioblastoma and other cancers through TGF-β inhibition.Oncotarget2019
31811117Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target.Exp Mol Med2019
30898893PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma.J Exp Med2019
29048560Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.Neuro Oncol2018
29844123Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.Cancer Res2018
30262818Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy.Nat Genet2018
29129044Anti-SEMA3A Antibody: A Novel Therapeutic Agent to Suppress Glioblastoma Tumor Growth.Cancer Res Treat2018
28903422CDK4/6 inhibition is more active against the glioblastoma proneural subtype.Oncotarget2017
28164090MET: roles in epithelial-mesenchymal transition and cancer stemness.Ann Transl Med2017
28814434Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms.Clin Cancer Res2017
28754668Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling.Cancer Res2017
28512247Targetable T-type Calcium Channels Drive Glioblastoma.Cancer Res2017
26032834USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance.Neuro Oncol2016
26641068WNT signaling in glioblastoma and therapeutic opportunities.Lab Invest2016
26751204Correction: Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.PLoS Biol2016
26893731Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges.Oncol Lett2016
24488013EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.Oncogene2015
26673326Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.Cell Rep2015
26373279Spatiotemporal Evolution of the Primary Glioblastoma Genome.Cancer Cell2015
26444992FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.PLoS One2015
26336988Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme.Oncotarget2015
26023737In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma.Oncotarget2015
25992628Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.PLoS Biol2015
25601206EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner.Stem Cell Reports2015
24440720ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.Cell Rep2014
25364264Targeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signaling.Onco Targets Ther2014
23154965Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.Cancer Discov2013
23684459Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells.Cancer Cell2013
23651857Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.Genes Dev2013
23381625Radiosensitization of brain metastasis by targeting c-MET.Lab Invest2013
23258844Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells.Neuro Oncol2013
23333277Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ.Cell Rep2013
22083670Wnt activation is implicated in glioblastoma radioresistance.Lab Invest2012
22661233Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.Genes Dev2012
22617325MET signaling regulates glioblastoma stem cells.Cancer Res2012
21481791Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.Cancer Cell2011
21771732Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.J Natl Cancer Inst2011
21602932Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.PLoS One2011
21729780Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.Cell2011
20186265Targeting A20 decreases glioma stem cell survival and tumor growth.PLoS Biol2010
19427293SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.Cell Stem Cell2009
19955368The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors.J Neurosci2009
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Collaborators

Do-Hyun Nam
Samsung Medical Center, Sungkyunkwan University School
Co-authored papers 28
Howard A Fine
Meyer Cancer Center
Co-authored papers 16
Kyeung Min Joo
Cancer Stem Cell Research Center, Samsung Biomedical Research Institute
Co-authored papers 13
Jin-Ku Lee
Seoul National University, College of Medicine
Co-authored papers 11
Hee Jin Cho
Touro College of Osteopathic Medicine
Co-authored papers 11
Jason K Sa
Korea University, College of Medicine
Co-authored papers 10
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Gangnam Severance Hospital
Co-authored papers 8
Ho Jun Seol
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 8
Jong Bae Park
Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan University
Co-authored papers 8
Jeremy N Rich
UPMC Hillman Cancer Center, University of Pittsburgh Medical Center
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Donggeon Kim
Institute for Refractory Cancer Research, Samsung Medical Center
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Doo-Sik Kong
Samsung Medical Center, Sungkyunkwan University School of Medicine
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Cancer Stem Cell Research Center, Samsung Biomedical Research Institute
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Misuk Kim
Inha University
Co-authored papers 7
Yeup Yoon
Sungkyunkwan University
Co-authored papers 6
Sung Soo Kim
Institute of Vision Research, Yonsei University College of Medicine
Co-authored papers 5
Heon Yoo
Neuro-Oncology Clinic, National Cancer Center
Co-authored papers 5
Ho-Shin Gwak
National Cancer Center
Co-authored papers 5
Jong Heon Kim
Research Institute, National Cancer Center
Co-authored papers 5
Agnieszka Bronisz
Mossakowski Medical Research Institute, Polish Academy of Sciences
Co-authored papers 5
Qin Su
Co-authored papers 4
Anita B Hjelmeland
University of Alabama at Birmingham
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Seung Hoon Lee
Korea University College of Medicine, Korea University Ansan Hospital
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Erik P Sulman
NYU Grossman School of Medicine
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Woong-Yang Park
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Release 1.2