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Author Details

Jos?? N Nobrega
University of Toronto
1978
213
44
PMIDPaper TitleJournal TitlePublished Year
34982171Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3.Psychopharmacology (Berl)2022
36112867Cell-based serum anticholinergic activity assay and working memory in cognitively healthy older adults before and after scopolamine: An exploratory study.J Psychopharmacol2022
33399315Global DNA methylation in suicidal ideation and suicide attempt in schizophrenia.Psychiatr Genet2021
33908307Antidepressant action of transcranial direct current stimulation in olfactory bulbectomised adolescent rats.J Psychopharmacol2021
33846084Relationships Between a New Cultured Cell-Based Serum Anticholinergic Activity Assay and Anticholinergic Burden Scales or Cognitive Performance in Older Adults.Am J Geriatr Psychiatry2021
34481920A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods.J Pharmacol Toxicol Methods2021
31504265A Key Role for Prefrontocortical Small Conductance Calcium-Activated Potassium Channels in Stress Adaptation and Rapid Antidepressant Response.Cereb Cortex2020
31905371Effects of exposure to chronic uncertainty and a sensitizing regimen of amphetamine injections on locomotion, decision-making, and dopamine receptors in rats.Neuropsychopharmacology2020
31962287Endocannabinoid modulating drugs improve anxiety but not the expression of conditioned fear in a rodent model of post-traumatic stress disorder.Neuropharmacology2020
31775159D3 dopamine receptors and a missense mutation of fatty acid amide hydrolase linked in mouse and men: implication for addiction.Neuropsychopharmacology2020
30796492Rostrocaudal subregions of the ventral tegmental area are differentially impacted by chronic stress.Psychopharmacology (Berl)2019
31302721Ethanol-induced changes in synaptic amino acid neurotransmitter levels in the nucleus accumbens of differentially sensitized mice.Psychopharmacology (Berl)2019
31265251In Vivo Brain Sampling Using a Microextraction Probe Reveals Metabolic Changes in Rodents after Deep Brain Stimulation.Anal Chem2019
28919158A role for nucleus accumbens glutamate in the expression but not the induction of behavioural sensitization to ethanol.Behav Brain Res2018
29727711High frequency stimulation of the anterior vermis modulates behavioural response to chronic stress: involvement of the prefrontal cortex and dorsal raphe?Neurobiol Dis2018
29505786Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system.Neuropharmacology2018
29174865Deep brain stimulation induces antidepressant-like effects in serotonin transporter knockout mice.Brain Stimul2018
29326057Antidepressant effects of focused ultrasound induced blood-brain-barrier opening.Behav Brain Res2018
28862251Prefrontal Cortex Deep Brain Stimulation Improves Fear and Anxiety-Like Behavior and Reduces Basolateral Amygdala Activity in a Preclinical Model of Posttraumatic Stress Disorder.Neuropsychopharmacology2018
27565433Lipoic acid and haloperidol-induced vacuous chewing movements: Implications for prophylactic antioxidant use in tardive dyskinesia.Prog Neuropsychopharmacol Biol Psychiatry2017
28485732Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse.Transl Psychiatry2017
28274871An improved, high-efficiency assay for assessing serum anticholinergic activity using cultured cells stably expressing M1 receptors.J Pharmacol Toxicol Methods2017
28454738Rat brain CYP2D enzymatic metabolism alters acute and chronic haloperidol side-effects by different mechanisms.Prog Neuropsychopharmacol Biol Psychiatry2017
28477491Basal forebrain mediated increase in brain CRF is associated with increased cholinergic tone and depression.Psychiatry Res Neuroimaging2017
28596119Alterations of M1 and M4 acetylcholine receptors in the genetically dystonic (dt<sup>sz</sup>) hamster and moderate antidystonic efficacy of M1 and M4 anticholinergics.Neuroscience2017
28719807Evaluation of a novel radiotracer for positron emission tomography imaging of reactive oxygen species in the central nervous system.Nucl Med Biol2017
27650910Inhibition of fatty acid amide hydrolase by BIA 10-2474 in rat brain.J Cereb Blood Flow Metab2017
27087270Increased Seasonal Variation in Serotonin Transporter Binding in Seasonal Affective Disorder.Neuropsychopharmacology2016
26553166Lower KV7.5 Potassium Channel Subunit Expression in an Animal Model of Paroxysmal Dystonia.CNS Neurol Disord Drug Targets2016
26525655Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature.Neuroimage2016
27857171Strong interactions between learned helplessness and risky decision-making in a rat gambling model.Sci Rep2016
27553523Serotonin transporter binding is reduced in seasonal affective disorder following light therapy.Acta Psychiatr Scand2016
26747370The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus.Eur Neuropsychopharmacol2016
26987629Reply to: Deep Brain Stimulation for Depression: Is It a Gray or White "Matter"?Biol Psychiatry2016
26932819Deep Brain Stimulation in Animal Models of Fear, Anxiety, and Posttraumatic Stress Disorder.Neuropsychopharmacology2016
26708208Localized brain differences in Arc expression between mice showing low vs. high propensity to ethanol sensitization.Pharmacol Biochem Behav2016
24642732Effects of high-frequency stimulation of the nucleus accumbens on the development and expression of ethanol sensitization in mice.Behav Pharmacol2015
26431907Rapid anti-depressant and anxiolytic actions following dopamine D1-D2 receptor heteromer inactivation.Eur Neuropsychopharmacol2015
26529427Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed rats.Transl Psychiatry2015
26340045Changes in dendritic spine density in the nucleus accumbens do not underlie ethanol sensitization.Synapse2015
26337974Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats.J Neuroinflammation2015
26106299Deep brain stimulation of the subthalamic nucleus preferentially alters the translational profile of striatopallidal neurons in an animal model of Parkinson's disease.Front Cell Neurosci2015
26228396Acute high frequency stimulation of the prefrontal cortex or nucleus accumbens does not increase hippocampal neurogenesis in rats.J Psychiatr Res2015
25842268Chronic deep brain stimulation of the rat ventral medial prefrontal cortex disrupts hippocampal-prefrontal coherence.Exp Neurol2015
25891484Light therapy and serotonin transporter binding in the anterior cingulate and prefrontal cortex.Acta Psychiatr Scand2015
25835354Antidepressant-like Effects of Medial Forebrain Bundle Deep Brain Stimulation in Rats are not Associated With Accumbens Dopamine Release.Brain Stimul2015
25661529Behavioral effects of food-derived opioid-like peptides in rodents: Implications for schizophrenia?Pharmacol Biochem Behav2015
25575638Towards a better preclinical model of PTSD: characterizing animals with weak extinction, maladaptive stress responses and low plasma corticosterone.J Psychiatr Res2015
25283483Low dose pramipexole causes D3 receptor-independent reduction of locomotion and responding for a conditioned reinforcer.Neuropharmacology2015
25266122Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models.Mol Psychiatry2015
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Collaborators

Roger Raymond
Campbell Family Mental Health Research Institute and Research Imaging Center
Co-authored papers 42
Paul J Fletcher
Campbell Family Mental Health Research Institute, University of Toronto
Co-authored papers 21
James L Kennedy
Institute of Medical Sciences, University of Toronto
Co-authored papers 4
Glen B Baker
Neurochemical Research Unit, University of Alberta
Co-authored papers 3
Albert H C Wong
Campbell Family Mental Health Research Institute
Co-authored papers 2
Nir Lipsman
University of Toronto
Co-authored papers 2
Hubert H M Van Tol
Clarke Institute of Psychiatry
Co-authored papers 2
Jacob Ellegood
Hospital for Sick Children
Co-authored papers 1
Franco J Vaccarino
University of Guelph
Co-authored papers 1
Laura A Feldcamp
Institute of Medical Science, University of Toronto
Co-authored papers 1
Jo Knight
Data Science Institute and Lancaster University Medical School
Co-authored papers 1
Frankie H F Lee
Campbell Family Mental Health Research Institute
Co-authored papers 1
Mallar Chakravarty
McGill University
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
John C Roder
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 1
Michel J Grothe
Instituto de Salud Carlos III
Co-authored papers 1
Jason P Lerch
The Hospital for Sick Children, University of Oxford, University of Toronto
Co-authored papers 1
Tatiana V Lipina
Institute of Neurosciences and Medicine
Co-authored papers 1
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