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Author Details

Hanneke Vlaming
Blavatnik Institute, Harvard Medical School
2012
14
10
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36425063DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors <i>in vitro</i>.Front Genet2022
35681023Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential.Nat Struct Mol Biol2022
33949091Strength is in engagement: The rise of an online scientific community during the COVID-19 pandemic.EMBO Rep2021
34140538Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies.Sci Rep2021
32764145The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8<sup>+</sup> T cells.Proc Natl Acad Sci U S A2020
31304633Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.EMBO J2019
30203048Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.Nucleic Acids Res2018
26728620The upstreams and downstreams of H3K79 methylation by DOT1L.Chromosoma2016
27922451Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1.Elife2016
25533186Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.Mol Cell2015
25965993Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.Sci Rep2015
25648995HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.FASEB J2015
25141862Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.EMBO Rep2014
22332652Crosstalk between aging and the epigenome.Epigenomics2012
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Collaborators

Fred van Leeuwen
Netherlands Cancer Institute, University of Amsterdam
Co-authored papers 11
Tibor van Welsem
Netherlands Cancer Institute
Co-authored papers 7
Tessy Korthout
Oncode Institute
Co-authored papers 4
Haico van Attikum
Leiden University Medical Center
Co-authored papers 3
Thom M Molenaar
Amsterdam UMC location Vrije Universiteit Amsterdam
Co-authored papers 3
Iris J E Stulemeijer
Netherlands Cancer Institute
Co-authored papers 2
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 2
Kirsten van Harten
Netherlands Cancer Institute
Co-authored papers 2
Rohith Srivas
Amgen Inc.
Co-authored papers 2
Deepani W Poramba-Liyanage
Utrecht University Utrecht The Netherlands.
Co-authored papers 2
Albert J R Heck
Utrecht University
Co-authored papers 1
Jan Paul Medema
Oncode Institute
Co-authored papers 1
Huib Ovaa
Leiden University Medical Center
Co-authored papers 1
Kenji Shimada
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 1
Leonie Kollenstart
Leiden University Medical Center
Co-authored papers 1
Dominique Morais
Netherlands Cancer Institute
Co-authored papers 1
Kees Vreeken
Leiden University Medical Center
Co-authored papers 1
Andrew Seeber
Center for Advanced Imaging, Harvard University
Co-authored papers 1
Aude Gu??nol??
CNRS, Universite de Toulouse
Co-authored papers 1
Farid El Oualid
The Netherlands Cancer Institute
Co-authored papers 1
Nicole Hustedt
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 1
Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 1
Susan M Gasser
L'Institut Suisse de Recherche Experimentale sur le Cancer (ISREC) Foundation
Co-authored papers 1
Monika Tsai-Pflugfelder
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 1
Bhupinder Bhullar
Novartis Institute for Biomedical Research
Co-authored papers 1
Ragna Sack
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 1
Tineke L Lenstra
the Netherlands Cancer Institute, Oncode Institute
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Su Ming Sun
Leiden University Medical Center
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Reggy Ekkebus
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