Author details

Full Name

Thomas Eschenhagen

Affiliation

ORCID

Career Start Year

1990

Papers

376

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36980219	Proteomic Analysis in Valvular Cardiomyopathy: Aortic Regurgitation vs. Aortic Stenosis.		2023
37922915	A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM.		2023
37802072	Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism.		2023
37572973	Organ-specific model of simulated ischemia/reperfusion and hyperglycemia based on engineered heart tissue.		2023
38091955	A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM.		2023
37620858	An arrhythmogenic metabolite in atrial fibrillation.		2023
37863976	Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES.		2023
36884078	The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies.	Clin Res Cardiol	2023
36763906	Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation.		2023
36875015	Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective.		2023
37109251	Valvular Cardiomyopathy in Aortic Valve Regurgitation Correlates with Myocardial Fibrosis.		2023
36927180	Hypoxia to Stimulate Cardiomyocyte Proliferation After MI? A Word of Caution.		2023
36681268	Resting membrane potential is less negative in trabeculae from right atrial appendages of women, but action potential duration does not shorten with age.		2023
37105188	[Cardiac biomarkers and their clinical relevance].		2023
35325615	PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.	Cell Stem Cell	2022
35581325	Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes.	Scientific Reports	2022
35954268	Regulation of APD and Force by the Na/Ca Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue.	Cells	2022
36078153	<i>ACTN2</i> Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes.	Cells	2022
36073365	Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury.	Circulation	2022
35938313	Disease modeling of a mutation in Î±-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.	EMBO Molecular Medicine	2022
35618905	Human-Engineered Atrial Tissue for Studying Atrial Fibrillation.	Methods in Molecular Biology	2022
35923092	Activation of an accessory pathway of glucose metabolism to treat dilated cardiomyopathy.	European Heart Journal	2022
34687723	How to repair a broken heart with pluripotent stem cell-derived cardiomyocytes.	Journal of Molecular and Cellular Cardiology	2022
34634355	Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue.	Journal of Molecular and Cellular Cardiology	2022
35218664	A potential future Fontan modification: preliminary in vitro data of a pressure-generating tube from engineered heart tissue.	European Journal of Cardio-thoracic Surgery	2022
35030072	Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations.	American Journal of Physiology - Heart and Circulatory Physiology	2022
34969177	Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC).	Eur J Heart Fail	2022
35170489	Muscarinic Receptor Activation Reduces Force and Arrhythmias in Human Atria Independent of IK,ACh.	Journal of Cardiovascular Pharmacology	2022
34999816	Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart.	Cardiovasc Res	2022
34805146	Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.	Frontiers in Cell and Developmental Biology	2021
32365197	Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function.	Cardiovasc Res	2021
33741918	Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?	Nature Communications	2021
33582159	Hypertrophic signaling compensates for contractile and metabolic consequences of DNA methyltransferase 3A loss in human cardiomyocytes.	Journal of Molecular and Cellular Cardiology	2021
33957110	Translational investigation of electrophysiology in hypertrophic cardiomyopathy.	Journal of Molecular and Cellular Cardiology	2021
33677066	Regulation of basal and norepinephrine-induced cAMP and I in hiPSC-cardiomyocytes: Effects of culture conditions and comparison to adult human atrial cardiomyocytes.	Cellular Signalling	2021
33998164	Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.	EMBO Mol Med	2021
33619556	Blunted beta-adrenoceptor-mediated inotropy in valvular cardiomyopathy: another piece of the puzzle in human aortic valve disease.	European Journal of Cardio-thoracic Surgery	2021
33997522	FYCO1 Regulates Cardiomyocyte Autophagy and Prevents HeartÂ Failure Due to Pressure Overload InÂ Vivo.	JACC: Basic to Translational Science	2021
33939531	Statins Do More Than Lower Cholesterol-Depending on What You Eat?	Circulation	2021
33831709	Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue.	Redox Biology	2021
33648345	Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner.	Circulation	2021
33064963	Cardiac Regeneration: New Hope for an Old Dream.	Annual Review of Physiology	2021
32949251	Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.	Naunyn-Schmiedeberg's Archives of Pharmacology	2021
33002334	No impact of sex and age on beta-adrenoceptor-mediated inotropy in human right atrial trabeculae.	Acta Physiologica	2021
34673795	Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease.	PLoS ONE	2021
34375846	Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy.	Stem Cell Research	2021
34948294	Characterization of the PLN p.Arg14del Mutation in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.	International Journal of Molecular Sciences	2021
30954570	Human pluripotent stem cell-derived cardiomyocytes for studying energy metabolism.	Biochimica et Biophysica Acta - Molecular Cell Research	2020
32268149	An epidemiological study exploring a possible impact of treatment with ACE inhibitors or angiotensin receptor blockers on ACE2 plasma concentrations.	Journal of Molecular and Cellular Cardiology	2020
31598634	Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue.	Cardiovascular Research	2020