Author details

Full Name

Yang Wang

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36976016	Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.		2023
36893269	Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.	Proc Natl Acad Sci U S A	2023
37455569	Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi.		2023
37040833	Formulation Studies to Develop Low-Cost, Orally-Delivered Secretory IgA Monoclonal Antibodies for Passive Immunization Against Enterotoxigenic Escherichia coli.		2023
35323111	Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.	Elife	2022
36172366	Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.	Front Immunol	2022
36350351	Human B Cell Epitope Map of the Lyme Disease Vaccine Antigen, OspA.	ACS Infectious Diseases	2022
36000876	Agglutination of Borreliella burgdorferi by Transmission-Blocking OspA Monoclonal Antibodies and Monovalent Fab Fragments.	Infection and Immunity	2022
35672343	A cocktail of human monoclonal antibodies broadly neutralizes North American rabies virus variants as a promising candidate for rabies post-exposure prophylaxis.	Scientific Reports	2022
34790979	Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.	bioRxiv	2021
33914704	Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody.	Journal of Clinical Investigation	2021
33531570	Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design.	Sci Rep	2021
33439092	Investigation of a monoclonal antibody against enterotoxigenic , expressed as secretory IgA1 and IgA2 in plants.	Gut Microbes	2021
31369743	Preformulation Characterization and Stability Assessments of Secretory IgA Monoclonal Antibodies as Potential Candidates for Passive Immunization by Oral Administration.	Journal of Pharmaceutical Sciences	2020
32008877	Oral administration of an anti-CfaE secretory IgA antibody protects against Enterotoxigenic Escherichia coli diarrheal disease in a nonhuman primate model.	Vaccine	2020
32826914	A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction.	Nat Commun	2020
33041102	IgA as a potential candidate for enteric monoclonal antibody therapeutics with improved gastrointestinal stability.	Vaccine	2020
32511396	IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity.	bioRxiv	2020
33121367	Highly Specific Mouse Anti-Joining Chain of Human Immunoglobulin A.	Monoclonal Antibodies in Immunodiagnosis and Immunotherapy	2020
30476132	Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing Immunity in Mice.	J Infect Dis	2019
31636239	Inhibition of Allergic Reactivity through Targeting FcÎµRI-Bound IgE with Humanized Low-Affinity Antibodies.	Journal of Immunology	2019
29866909	Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection.	Infection and Immunity	2018
30459206	Correction for Giuntini et al., "Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis against Enterotoxigenic Escherichia coli Infection".	Infection and Immunity	2018
28127942	Prevention of allograft HCV recurrence with peri-transplant human monoclonal antibody MBL-HCV1 combined with a single oral direct-acting antiviral: A proof-of-concept study.	J Viral Hepat	2017
28794021	Structure-Based Design of Hepatitis C Virus Vaccines That Elicit Neutralizing Antibody Responses to a Conserved Epitope.	J Virol	2017
27859766	Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions.	J Mol Recognit	2017
27338767	Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes.	Journal of Infectious Diseases	2016
26018774	A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.	mAbs	2015
26042465	Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia.	International Journal of Molecular Sciences	2015
24956119	High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody.	PLoS One	2014
25484044	Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches.	MAbs	2014
23613814	Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1.	PLoS ONE	2013
23940209	Identification of a human monoclonal antibody to replace equine diphtheria antitoxin for treatment of diphtheria intoxication.	Infection and Immunity	2013
22952447	Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.	PLoS Pathogens	2012
21693135	G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates.	Antiviral Research	2011