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Author Details

Stephen L Hoffman
Inc., 9800 Medical Center Drive
1980
445
92
PMIDPaper TitleJournal TitlePublished Year
36753561Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.Sci Transl Med2023
37563050Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates.Vaccine2023
37609210Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria.Res Sq2023
37571809Sporozoite immunization: innovative translational science to support the fight against malaria.Expert Rev Vaccines2023
38093306Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research.Malar J2023
37160281Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults.Am J Trop Med Hyg2023
37082831Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies.EMBO Mol Med2023
37384799The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.PLoS Pathog2023
37310872The Dantu blood group prevents parasite growth <i>in vivo</i>: Evidence from a controlled human malaria infection study.Elife2023
37265668<i>Plasmodium</i> 18S Ribosomal RNA Biomarker Clearance After Food and Drug Administration-Approved Antimalarial Treatment in Controlled Human Malaria Infection Trials.Open Forum Infect Dis2023
34801112Safety and efficacy of a three-dose regimen of Plasmodium falciparum sporozoite vaccine in adults during an intense malaria transmission season in Mali: a randomised, controlled phase 1 trial.Lancet Infect Dis2022
35641527Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens.NPJ Vaccines2022
35697668Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa.Nat Commun2022
35715803Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial.Malar J2022
35687696Clonal evolution and TCR specificity of the human T<sub>FH</sub> cell response to <i>Plasmodium falciparum</i> CSP.Sci Immunol2022
36477528In vitro production of infectious Plasmodium falciparum sporozoites.Nature2022
36475905A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria.Sci Transl Med2022
36671393Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice.Biomolecules2022
35999221A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection.NPJ Vaccines2022
35928033PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial.EClinicalMedicine2022
36030292Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites.Malar J2022
35922467Immunological profiles associated with distinct parasitemic states in volunteers undergoing malaria challenge in Gabon.Sci Rep2022
36389797Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased protective efficacy.Front Immunol2022
35226868Cryopreserved Sporozoites with and without the Glycolipid Adjuvant 7DW8-5 Protect in Prime-and-Trap Malaria Vaccination.Am J Trop Med Hyg2022
35130487Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults.Am J Trop Med Hyg2022
35242146A First for Human Vaccinology: GMP Compliant Radiation Attenuation of <i>Plasmodium falciparum</i> Sporozoites for Production of a Vaccine Against Malaria.Front Immunol2022
34997079Cryopreservation of Anopheles stephensi embryos.Sci Rep2022
35331251Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea.Malar J2022
34710239An efficient single-cell based method for linking human T cell phenotype to T cell receptor sequence and specificity.Eur J Immunol2022
33438712Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines.Nanoscale2021
33713652Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes.Int J Parasitol2021
33567273Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans.Cell Rep2021
33815377Expansion of Functional Myeloid-Derived Suppressor Cells in Controlled Human Malaria Infection.Front Immunol2021
33888898Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity.Nat Immunol2021
33499880Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers.Virol J2021
33746641A Mosquito Pick-and-Place System for PfSPZ-based Malaria Vaccine Production.IEEE Trans Autom Sci Eng2021
34518679Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial.Nat Med2021
34518543Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome.NPJ Vaccines2021
34784388Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence.PLoS Pathog2021
34243763Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers.Malar J2021
34174879Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections.Malar J2021
34061838Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2.PLoS Negl Trop Dis2021
34170120Identification of the Glycan Binding Profile of Human and Rodent <i>Plasmodium</i> Sporozoites.ACS Infect Dis2021
34284778Incidence of Plasmodium falciparum malaria infection in 6-month to 45-year-olds on selected areas of Bioko Island, Equatorial Guinea.Malar J2021
34194041Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity.Nature2021
33947856Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial.Nat Commun2021
34048504PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection.PLoS Pathog2021
31402382Serologic Markers of Previous Malaria Exposure and Functional Antibodies Inhibiting Parasite Growth Are Associated With Parasite Kinetics Following a Plasmodium falciparum Controlled Human Infection.Clin Infect Dis2020
31808594Ivermectin for causal malaria prophylaxis: a randomised controlled human infection trial.Trop Med Int Health2020
32102854Recombinase Polymerase Amplification and Lateral Flow Assay for Ultrasensitive Detection of Low-Density Plasmodium falciparum Infection from Controlled Human Malaria Infection Studies and Naturally Acquired Infections.J Clin Microbiol2020
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Collaborators

US Military Malaria Vaccine Program, Naval Medical Research Center
Co-authored papers 30
J. Craig Venter Institute
Co-authored papers 19
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology
Co-authored papers 12
The J. Craig Venter Institute
Co-authored papers 12
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 9
Institute for Genome Research
Co-authored papers 9
J. Craig Venter Institute
Co-authored papers 8
Co-authored papers 7
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 7
Case Western Reserve University School of Medicine
Co-authored papers 6
Center for Computational Biology, Johns Hopkins University
Co-authored papers 6
Center for Genomics and Systems Biology
Co-authored papers 5
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 5
Co-authored papers 5
Oncology R&D
Co-authored papers 4
Seattle Children's Research Institute
Co-authored papers 4
Clinical Center
Co-authored papers 4
Center for Computational Biology, Johns Hopkins University
Co-authored papers 4
Personal Genome Diagnostics Inc.
Co-authored papers 4
John Hunter Children's Hospital
Co-authored papers 4
International Livestock Research Institute (ILRI)
Co-authored papers 3
The Institute for Genomic Research
Co-authored papers 3
TheScripps Research Institute
Co-authored papers 3
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 3
Qassim University
Co-authored papers 3
The Institute for Genomic Research, 9712 Medical Center Drive
Co-authored papers 3
Craig Venter Institute, 9704 Medical Center Drive
Co-authored papers 3
Center for Biomolecular Science and Engineering, University of California
Co-authored papers 3
University of Wisconsin-Madison
Co-authored papers 3
Co-authored papers 3