Skip to Main Content

Author Details

Philippe P Roux
IRIC - University of Montreal
1998
101
50
Sami Nourreddine (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37729615CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.Blood Adv2024
37311021HER2ο16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer.Cancer Immunol Res2023
37670013Author Correction: In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.Nat Commun2023
37258521In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.Nat Commun2023
35134350Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb.Curr Biol2022
36309522CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma.Nat Commun2022
35892282Proteomic analysis of the actin cortex in interphase and mitosis.J Cell Sci2022
35286394CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.Blood Adv2022
35167498Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation.JCI Insight2022
32233986Controversies around the function of LARP1.RNA Biol2021
33710330Correction: RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation.Biochem J2021
33930296Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation.Cell2021
34125833RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit.PLoS Genet2021
33434153Sustained ERK1/2 signaling is necessary for follicular rupture during ovulation in mice.Reproduction2021
32433969NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.Cell Rep2020
31928973F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis.Dev Cell2020
32075988Publisher Correction: Regulation of protein kinase Cδ Nuclear Import and Apoptosis by Mechanistic Target of Rapamycin Complex-1.Sci Rep2020
31917615Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling.Am J Respir Crit Care Med2020
31678930Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.Mol Cell Proteomics2020
33235918Targeting copper metabolism to defeat KRAS-driven colorectal cancer.Mol Cell Oncol2020
32572169SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization.Nat Cell Biol2020
32709883Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.Nat Commun2020
32727899An ErbB2 splice variant lacking exon 16 drives lung carcinoma.Proc Natl Acad Sci U S A2020
30728292ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation.Proc Natl Acad Sci U S A2019
31698461Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities.Blood Adv2019
31772273Regulation of protein kinase Cδ Nuclear Import and Apoptosis by Mechanistic Target of Rapamycin Complex-1.Sci Rep2019
31287994Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.Cancer Cell2019
31477736Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration.Nat Commun2019
31102422Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children.Genes Chromosomes Cancer2019
29719259The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.Cell Rep2018
28476656Defining the role of the RSK isoforms in cancer.Semin Cancer Biol2018
29610153Signaling Pathways Involved in the Regulation of mRNA Translation.Mol Cell Biol2018
29545927CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein.Oncotarget2018
29440170RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.Cancer Res2018
27872148Proteomics Screen Identifies Class I Rab11 Family Interacting Proteins as Key Regulators of Cytokinesis.Mol Cell Biol2017
28408459EPCR expression marks UM171-expanded CD34<sup>+</sup> cord blood stem cells.Blood2017
28096188Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.Mol Cell Biol2017
28416805A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.Nat Commun2017
28530659Actin cortex architecture regulates cell surface tension.Nat Cell Biol2017
28757207Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition.Mol Cell2017
27797342High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.J Clin Invest2016
25477072Translational control by oncogenic signaling pathways.Biochim Biophys Acta2015
26324936Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.Proc Natl Acad Sci U S A2015
26779414Regulation of global and specific mRNA translation by the mTOR signaling pathway.Translation (Austin)2015
25688110The expanding role of mTOR in cancer cell growth and proliferation.Mutagenesis2015
25803847Effect of the transient pharmacological inhibition of Mapk3/1 pathway on ovulation in mice.PLoS One2015
23584478Glycogen synthase kinase-3β positively regulates protein synthesis and cell proliferation through the regulation of translation initiation factor 4E-binding protein 1.Oncogene2014
25002506Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3.Proc Natl Acad Sci U S A2014
25028204A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells.Nat Commun2014
25017211Cellular control of cortical actin nucleation.Curr Biol2014
  • 1 - 50 of 101

Recommended Authors

Alexandre Rosa Campos
Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 2015
Number of shared co-authors 0
Rachel A O'Keefe
University of California San Francisco
Career Start Year 2013
Number of shared co-authors 0
Min Gao
College of Horticulture, China Agricultural University
Career Start Year 2012
Number of shared co-authors 0
Rebecca S Levin
Howard Hughes Medical Institute, University of California San Francisco
Career Start Year 2010
Number of shared co-authors 0
Gabriel Leprivier
Institute of Neuropathology, Heinrich-Heine University Dusseldorf
Career Start Year 2006
Number of shared co-authors 0
Severa Bunda
Princess Margaret Cancer Centre
Career Start Year 2005
Number of shared co-authors 1
Xing Guo
Life Sciences Institute, Zhejiang University
Career Start Year 2004
Number of shared co-authors 0
Ganna Panasyuk
Institut Necker-Enfants Malades (INEM)
Career Start Year 2002
Number of shared co-authors 0
Barak Rotblat
Ben-Gurion University of the Negev
Career Start Year 2002
Number of shared co-authors 0
Yong Jae Shin
Cancer Stem Cell Research Center, Samsung Biomedical Research Institute
Career Start Year 2001
Number of shared co-authors 0
Jason D Weber
Washington University School of Medicine
Career Start Year 1996
Number of shared co-authors 0
Michael A White
University of Georgia
Career Start Year 1994
Number of shared co-authors 0
Mingyao Liu
The Institute of Biomedical Sciences, East China Normal University
Career Start Year 1994
Number of shared co-authors 0
John Alan Diehl
Case Western Reserve University School of Medicine
Career Start Year 1993
Number of shared co-authors 0
Christoph Reinhard
Lilly Research Laboratories
Career Start Year 1992
Number of shared co-authors 0
Dario R Alessi
University of Dundee
Career Start Year 1992
Number of shared co-authors 0
John Easton
St Jude Children's Research Hospital
Career Start Year 1991
Number of shared co-authors 1
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Career Start Year 1990
Number of shared co-authors 5
Kun-Liang Guan
University of California San Diego
Career Start Year 1988
Number of shared co-authors 2
Wei Zhang
The University of Texas MD Anderson Cancer Center
Career Start Year 1988
Number of shared co-authors 0
Rakesh Kumar
Rutgers New Jersey Medical School
Career Start Year 1987
Number of shared co-authors 2
Deborah K Morrison
Center for Cancer Research, National Cancer Institute-Frederick
Career Start Year 1985
Number of shared co-authors 2
Michael F Moran
Hospital for Sick Children, University of Toronto
Career Start Year 1985
Number of shared co-authors 5
Jorge Silvio Gutkind
Moores Cancer Center, University of California San Diego
Career Start Year 1984
Number of shared co-authors 2
James R Woodgett
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Career Start Year 1982
Number of shared co-authors 5
Ze'ev Ronai
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 1981
Number of shared co-authors 1
Donald L Durden
Atrium Health-Levine Cancer Institute
Career Start Year 1979
Number of shared co-authors 0
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Career Start Year 1976
Number of shared co-authors 7
Frank McCormick
Frederick National Laboratory for Cancer Research
Career Start Year 1975
Number of shared co-authors 0
Tony Hunter
Salk Institute for Biological Studies
Career Start Year 1968
Number of shared co-authors 1

Collaborators

Genevi??ve Lavoie
Institute for Research in Immunology and Cancer (IRIC)
Co-authored papers 20
Joseph Tcherkezian
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 12
L??o Aubert
IRIC - University of Montreal
Co-authored papers 9
Steven P Gygi
Harvard Medical School
Co-authored papers 7
Antoine M??ant
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 6
Ewa K Paluch
University College London, University of Cambridge
Co-authored papers 6
Sami Nourreddine (CM4AI)
University of California San Diego
Co-authored papers 6
Guy Sauvageau
Universite de Montreal
Co-authored papers 5
S??bastien Carreno
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 4
Jalila Chagraoui
Institute for Research in Immunology and Cancer, University of Montreal
Co-authored papers 4
Thibault Houles
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 4
Marie-Jos??e H??bert
Universite de Montreal
Co-authored papers 4
Justine S Paradis
Moores Cancer Center, University of California San Diego
Co-authored papers 4
Sylvain Meloche
Institute for Research in Immunology and Cancer
Co-authored papers 4
Michel Bouvier
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 4
Patrick Gendron
University of Montreal
Co-authored papers 3
Louis Gaboury
Institute for Research in Immunology and Cancer (IRIC), University of Montreal
Co-authored papers 3
Asha L Bhakar
Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Co-authored papers 3
Marc K Saba-El-Leil
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 3
Neethi Nandagopal
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 3
Ivan Topisirovic
McGill University
Co-authored papers 3
Edward L Huttlin
Harvard Medical School
Co-authored papers 3
Benoit Grondin
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 3
Iman Fares
Dana-Farber Cancer Institute
Co-authored papers 2
Khaled Ben El Kadhi
New York University
Co-authored papers 2
Lewis C Cantley
Co-authored papers 2
Murielle P Serres
Institut Pasteur, Universite de Paris, CNRS UMR3691
Co-authored papers 2
Sichun Lin
Department of Pharmaceutical Sciences, University of Toronto
Co-authored papers 2
Stephane Angers
Department of Pharmaceutical Sciences, University of Toronto
Co-authored papers 2
Guy A Rouleau
McGill University, Canada Montreal Neurological Institute and Hospital
Co-authored papers 2
Release 1.2