Author details

Full Name

Jarek Meller

Affiliation

ORCID

Career Start Year

1998

Papers

103

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36580595	Opinion: Protein folds vs. protein folding: Differing questions, different challenges.	Proc Natl Acad Sci U S A	2023
34968947	The active kinome: The modern view of how active protein kinase networks fit in biological research.	Current Opinion in Pharmacology	2022
35945222	Connecting omics signatures and revealing biological mechanisms with iLINCS.	Nat Commun	2022
35866580	Rhesus rotavirus receptor-binding site affects high mobility group box 1 release, altering the pathogenesis ofÂ experimental biliary atresia.	Hepatology Communications	2022
32604402	Signature-based approaches for informed drug repurposing: targeting CNS disorders.		2021
33860076	Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking.	Molecular and Cellular Oncology	2021
33803184	Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma.	Genes	2021
34166366	Exposure to traffic-related air pollution and bacterial diversity in the lower respiratory tract of children.	PLoS ONE	2021
33627767	Identification of candidate repurposable drugs to combat COVID-19 using a signature-based approach.	Sci Rep	2021
34272489	Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.	Molecular Psychiatry	2021
33988680	Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide.	Journal of Cell Biology	2021
32970633	Tobacco smoking induces metabolic reprogramming of renal cell carcinoma.	Journal of Clinical Investigation	2021
32969526	The mycobiomes and bacteriomes of sputum, saliva, and home dust.	Indoor Air	2021
33291616	Transcriptional Regulation of Cancer Immune Checkpoints: Emerging Strategies for Immunotherapy.	Vaccines	2020
32163428	IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.	PLoS One	2020
32702077	Identification of new drug treatments to combat COVID19: A signature-based approach using iLINCS.	Res Sq	2020
31106784	Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia.	Mol Omics	2019
30254339	Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization.	Leukemia	2019
30338483	Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments.	Mol Neurobiol	2019
30639570	Enrichment of Genomic Pathways Based on Differential DNA Methylation Associated With Chronic Postsurgical Pain and Anxiety in Children: A Prospective, Pilot Study.	J Pain	2019
29199020	The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.	Cell Syst	2018
28803198	Variability of indoor fungal microbiome of green and non-green low-income homes in Cincinnati, Ohio.	Science of the Total Environment	2018
28440342	Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.	Pharmacogenomics J	2018
30333166	Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.	J Virol	2018
29140462	Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.	Nucleic Acids Res	2018
27859498	The SRL peptide of rhesus rotavirus VP4 protein governs cholangiocyte infection and the murine model of biliary atresia.	Hepatology	2017
28634427	Leveraging Food and Drug Administration Adverse Event Reports for the Automated Monitoring of Electronic Health Records in a Pediatric Hospital.	Biomed Inform Insights	2017
28900113	Abnormalities of signal transduction networks in chronic schizophrenia.	NPJ Schizophr	2017
28515290	A Point Mutation in the Rhesus Rotavirus VP4 Protein Generated through a Rotavirus Reverse Genetics System Attenuates Biliary Atresia in the Murine Model.	Journal of Virology	2017
26810133	ABCC3 genetic variants are associated with postoperative morphine-induced respiratory depression and morphine pharmacokinetics in children.	Pharmacogenomics J	2017
27312729	Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression.	Journal of Neurotrauma	2017
28031034	UQlust: combining profile hashing with linear-time ranking for efficient clustering and analysis of big macromolecular data.	BMC Bioinformatics	2016
26603840	The genetic fingerprint of susceptibility for transplant-associated thrombotic microangiopathy.	Blood	2016
26073558	Comprehensive analysis of sequences of a protein switch.	Protein Sci	2016
26419724	Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance.	Sci Rep	2015
25706094	Increased susceptibility of estrogen-induced bladder outlet obstruction in a novel mouse model.	Laboratory Investigation	2015
25825487	Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme.	J Biol Chem	2015
25318106	Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak.	American Journal of Physiology - Cell Physiology	2015
25311385	Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics.	Pharmacogenomics J	2015
25558980	Novel associations between FAAH genetic variants and postoperative central opioid-related adverse effects.	Pharmacogenomics J	2015
26206856	Rhesus rotavirus VP4 sequence-specific activation of mononuclear cells is associated with cholangiopathy in murine biliary atresia.	American Journal of Physiology - Gastrointestinal and Liver Physiology	2015
24913497	Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells.	International Journal of Oncology	2014
25455859	Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.	Chem Biol	2014
25331035	Association of Streptomyces community composition determined by PCR-denaturing gradient gel electrophoresis with indoor mold status.	Environmental Monitoring and Assessment	2014
25493568	Genetic risk signatures of opioid-induced respiratory depression following pediatric tonsillectomy.	Pharmacogenomics	2014
25517751	TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.	Cancer Cell	2014
23466888	Canonical Bcl-2 motifs of the Na+/K+ pump revealed by the BH3 mimetic chelerythrine: early signal transducers of apoptosis?	Cellular Physiology and Biochemistry	2013
23894462	Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections.	PLoS ONE	2013
23922894	Folliculin contributes to VHL tumor suppressing activity in renal cancer through regulation of autophagy.	PLoS ONE	2013
23141588	Substrate specificity of Tulane virus protease.	Virology	2013