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Author Details

Shepherd H Schurman
Clinical Research Unit, National Institute on Aging
1990
46
22
PMIDPaper TitleJournal TitlePublished Year
38052484Aging and Inflammation.Cold Spring Harb Perspect Med2024
36383734Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort.Diabetes Care2023
37558924Race-specific association of an IRGM risk allele with cytokine expression in human subjects.Sci Rep2023
37900350An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges.J Clin Transl Sci2023
36460922The skin is no barrier to mixtures: Air pollutant mixtures and reported psoriasis or eczema in the Personalized Environment and Genes Study (PEGS).J Expo Sci Environ Epidemiol2023
36527873Association of distance to swine concentrated animal feeding operations with immune-mediated diseases: An exploratory gene-environment study.Environ Int2023
35605674Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study.Environ Res2022
33444353UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin.PLoS Genet2021
34591792sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae.J Clin Invest2021
34326490Exploring the motivations of research participants who chose not to learn medically actionable secondary genetic findings about themselves.Genet Med2021
34283031A Biomedical Knowledge Graph System to Propose Mechanistic Hypotheses for Real-World Environmental Health Observations: Cohort Study and Informatics Application.JMIR Med Inform2021
32371551The COronavirus Pandemic Epidemiology (COPE) Consortium: A Call to Action.Cancer Epidemiol Biomarkers Prev2020
32060608TLR5 Activation Exacerbates Airway Inflammation in Asthma.Lung2020
31757180DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes.Cell Cycle2020
31759816Transethnic associations among immune-mediated diseases and single-nucleotide polymorphisms of the aryl hydrocarbon response gene ARNT and the PTPN22 immune regulatory gene.J Autoimmun2020
33219026Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes.Sci Adv2020
32798798Pharmacokinetics of bisphenol A in humans following dermal administration.Environ Int2020
32708093Translator Exposure APIs: Open Access to Data on Airborne Pollutant Exposures, Roadway Exposures, and Socio-Environmental Exposures and Use Case Application.Int J Environ Res Public Health2020
32849908A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging?Immun Ageing2020
30335469Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.Am J Physiol Gastrointest Liver Physiol2019
31707363Age-associated changes in human CD4<sup>+</sup> T cells point to mitochondrial dysfunction consequent to impaired autophagy.Aging (Albany NY)2019
31430261p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus.J Clin Invest2019
29275161Aging, inflammation and the environment.Exp Gerontol2018
30152570Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming.Stem Cells2018
30140039Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity.Sci Rep2018
28733462Human T cell immunosenescence and inflammation in aging.J Leukoc Biol2017
27788131The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.PLoS Genet2016
26309242Bisphenol A, Bisphenol S, and 4-Hydroâ¿¿xyphenyl 4-Isoproâ¿¿oxyphenylâ¿¿sulfone (BPSIP) in Urine and Blood of Cashiers.Environ Health Perspect2016
24703498Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance.Acta Physiol (Oxf)2015
26115537Pharmacokinetics of bisphenol A in humans following a single oral administration.Environ Int2015
22968453Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.Blood2012
23029205Age-related disease association of endogenous γ-H2AX foci in mononuclear cells derived from leukapheresis.PLoS One2012
20222902The involvement of human RECQL4 in DNA double-strand break repair.Aging Cell2010
18978338Base excision repair of oxidative DNA damage and association with cancer and aging.Carcinogenesis2009
19567405Direct and indirect roles of RECQL4 in modulating base excision repair capacity.Hum Mol Genet2009
17937437Cartilage hair hypoplasia mutations that lead to RMRP promoter inefficiency or RNA transcript instability.Am J Med Genet A2007
16353246Echocardiographic findings in classical and hypermobile Ehlers-Danlos syndromes.Am J Med Genet A2006
16091449Analysis of T-cell repertoire diversity in Wiskott-Aldrich syndrome.Blood2005
14504083Differential contribution of Wiskott-Aldrich syndrome protein to selective advantage in T- and B-cell lineages.Blood2004
15520879Klotho gene variation and expression in 20 inbred mouse strains.Mamm Genome2004
15142877Multiple patients with revertant mosaicism in a single Wiskott-Aldrich syndrome family.Blood2004
12456496Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.Blood2003
12819473Autoimmunity in Wiskott-Aldrich syndrome.Curr Opin Rheumatol2003
12727931Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings.J Clin Invest2003
11447283Somatic mosaicism in Wiskott--Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism.Proc Natl Acad Sci U S A2001
1689142Improved detection of metastases to lymph nodes and estrogen receptor determination.Arch Surg1990
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Collaborators

National Institute on Aging, National Institutes of Health
Co-authored papers 6
2Clinical Research Branch, National Institute of Environmental Health Sciences
Co-authored papers 6
National Institute of Environmental Health Science
Co-authored papers 6
National Institute of Environmental Health Sciences
Co-authored papers 4
Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill
Co-authored papers 3
Indiana University School of Medicine
Co-authored papers 2
National Institute of Environmental Health Sciences (NIEHS)
Co-authored papers 2
National Institute of Environmental Health Sciences (NIEHS)
Co-authored papers 2
Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill
Co-authored papers 2
Medical University of South Carolina
Co-authored papers 2
Co-authored papers 1
Co-authored papers 1
Cancer and Blood Disease Institute, Children's Hospital Los Angeles
Co-authored papers 1
Biodiversity Information Standards, Coastal and Estuarine Research Federation, Oregon State University, Phycological Society of America, Society of Professional Consultants, The Data Detektiv, University of Colorado Anschutz Medical Campus, University of Maryland College Park, Women in the Enterprise of Science and Technology
Co-authored papers 1
Renaissance Computing Institute (RENCI), University of North Carolina at Chapel Hill
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
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The Broad Institute of MIT and Harvard
Co-authored papers 1
University of Southern California
Co-authored papers 1
King's College London
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 1
The Hugh Kaul Precision Medicine Institute, University of Alabama at Birmingham
Co-authored papers 1
Institute for Systems Biology
Co-authored papers 1
Albert Einstein College of Medicine
Co-authored papers 1
Rady Children's Institute for Genomic Medicine, Rady Children's Hospital
Co-authored papers 1
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Institute for the Environment, University of North Carolina at Chapel Hill
Co-authored papers 1