Author details

Full Name

Xiaoying Shen

Affiliation

ORCID

Career Start Year

2007

Papers

105

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37797027	Mapping SARS-CoV-2 antigenic relationships and serological responses.	Science	2023
35860221	Mapping SARS-CoV-2 antigenic relationships and serological responses.	bioRxiv	2023
37854587	Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1.		2023
34933765	Towards a population-based threshold of protection for COVID-19 vaccines.	Vaccine	2022
36311720	Multi-trial analysis of HIV-1 envelope gp41-reactive antibodies among global recipients of candidate HIV-1 vaccines.	Frontiers in Immunology	2022
35503780	A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence.	PLoS Pathog	2022
35235790	Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies.	Cell Rep	2022
35081298	SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination.	N Engl J Med	2022
34931200	Booster of mRNA-1273 Strengthens SARS-CoV-2 Omicron Neutralization.	medRxiv	2021
33705729	SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines.		2021
33859204	Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans.	NPJ Vaccines	2021
33532764	SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines.		2021
34266981	A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.	Sci Immunol	2021
33837212	Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.	npj Vaccines	2021
33873199	Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.	Nature	2021
33826819	Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351.	New England Journal of Medicine	2021
34086838	Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.	PLoS Pathogens	2021
33554060	Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates.	iScience	2021
33594366	Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.	bioRxiv	2021
34743171	Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.	npj Vaccines	2021
33298954	Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs.	npj Vaccines	2020
32023469	Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization.	Cell Reports	2020
31896599	Expression of CD40L by the ALVAC-Simian Immunodeficiency Virus Vector Abrogates T Cell Responses in Macaques.	J Virol	2020
32402293	Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.	Cell Reports	2020
31827000	Impact of T1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.	Journal of Virology	2020
31776284	A MUC16 IgG Binding Activity Selects for a Restricted Subset of IgG Enriched for Certain Simian Immunodeficiency Virus Epitope Specificities.	J Virol	2020
32343743	Correction:Â ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.	PLoS Pathog	2020
32163525	Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.	PLoS Pathog	2020
32881968	Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge.	PLoS Pathog	2020
32820216	RhCMV serostatus and vaccine adjuvant impact immunogenicity of RhCMV/SIV vaccines.	Scientific Reports	2020
31048360	Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection.	Mol Syst Biol	2019
31653484	Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.	Cell Host Microbe	2019
30541851	Coadministration of CH31 Broadly Neutralizing Antibody Does Not Affect Development of Vaccine-Induced Anti-HIV-1 Envelope Antibody Responses in Infant Rhesus Macaques.	J Virol	2019
31092583	Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.	J Virol	2019
30700599	Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.	Journal of Virology	2019
31434737	Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial.	J Virol	2019
31263112	Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.	Nature Communications	2019
30778066	HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.	Nat Commun	2019
30776026	Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response.	J Clin Invest	2019
29785023	HIV vaccine candidate activation of hypoxia and the inflammasome in CD14<sup>+</sup> monocytes is associated with a decreased risk of SIV<sub>mac251</sub> acquisition.	Nat Med	2018
30089691	Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques.	J Virol	2018
30272013	IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells.	Communications Biology	2018
29386288	HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.	Journal of Virology	2018
29523166	Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.	Retrovirology	2018
29746590	Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.	PLoS Pathogens	2018
29698406	Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant.	PLoS One	2018
29325070	Modification of the Association Between T-Cell Immune Responses and Human Immunodeficiency Virus Type 1 Infection Risk by Vaccine-Induced Antibody Responses in the HVTN 505 Trial.	J Infect Dis	2018
29321320	HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.	Journal of Virology	2018
29237847	A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.	J Virol	2018
29793957	Control of Heterologous Simian Immunodeficiency Virus SIV<sub>smE660</sub> Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.	J Virol	2018