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Author Details

Eric Shifrut
Gladstone-UCSF Institute of Genomic Immunology
2012
26
22
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36008610High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails.Nat Biotechnol2023
35217172Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression.Mol Cell Proteomics2022
35365639A functional map of HIV-host interactions in primary human T cells.Nat Commun2022
36002574RASA2 ablation in T cells boosts antigen sensitivity and long-term function.Nature2022
33883145XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment.Sci Adv2021
32539073Layilin augments integrin activation to promote antitumor immunity.J Exp Med2020
31819258Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency.Nat Biotechnol2020
32989329Functional CRISPR dissection of gene networks controlling human regulatory T cell identity.Nat Immunol2020
32499641CRISPR screen in regulatory T cells reveals modulators of Foxp3.Nature2020
30833553Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire.Nat Commun2019
31359007Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.Nat Biotechnol2019
30449619Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.Cell2018
29995861Reprogramming human T cell function and specificity with non-viral genome targeting.Nature2018
30399156Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition.PLoS One2018
28073756Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.Bioinformatics2017
28481982McPAS-TCR: a manually curated catalogue of pathology-associated T cell receptor sequences.Bioinformatics2017
28450864Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization.Front Immunol2017
28731407T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences.Elife2017
26384546Perforin-Positive Dendritic Cells Exhibit an Immuno-regulatory Role in Metabolic Syndrome and Autoimmunity.Immunity2015
25095879Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.Bioinformatics2014
25024161T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity.Genome Res2014
23335631CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging.Proc Natl Acad Sci U S A2013
24312094CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.Front Immunol2013
23219532Dynamic response diversity of NFAT isoforms in individual living cells.Mol Cell2013
23072772Monitoring the dynamics of primary T cell activation and differentiation using long term live cell imaging in microwell arrays.Lab Chip2012
22984176Chromatin conformation governs T-cell receptor Jβ gene segment usage.Proc Natl Acad Sci U S A2012
  • 1 - 26 of 26

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Collaborators

Nir Friedman
Weizmann Institute of Science
Co-authored papers 14
Alexander Marson
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 12
Theodore L Roth
Stanford University
Co-authored papers 10
Jonathan M Woo
University of California san francisco
Co-authored papers 5
Victoria Tobin
California Institute of Technology
Co-authored papers 4
David N Nguyen
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 4
Julia Carnevale
University of California san francisco
Co-authored papers 4
Asaf Madi
Co-authored papers 3
Andrew P May
Fluidigm Corporation
Co-authored papers 3
Joseph B Hiatt
Fred Hutchinson Cancer Center
Co-authored papers 3
Ruby Yu
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 3
Alan Ashworth
UCSF Helen Diller Family Comprehensive Cancer Center
Co-authored papers 3
Kathrin Schumann
Institute for Medical Microbiology, Technical University of Munich (TUM)
Co-authored papers 2
Manuel D Leonetti
University of California, USA Howard Hughes Medical Institute san francisco
Co-authored papers 2
Morgan E Diolaiti
University of California San Francisco
Co-authored papers 2
Dimitre R Simeonov
University of California San Francisco
Co-authored papers 2
Judd F Hultquist
Northwestern University Feinberg School of Medicine
Co-authored papers 2
Fran??ois Van Laethem
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Ryan T Leenay
North Carolina State University
Co-authored papers 2
Youjin V Lee
University of Chicago
Co-authored papers 2
Chun Jimmie Ye
University of California san francisco
Co-authored papers 2
Lacy M Simons
Northwestern University Feinberg School of Medicine
Co-authored papers 1
James Zou
Stanford University
Co-authored papers 1
Hideho Okada
Co-authored papers 1
James A Wells
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 1
Cody T Mowery
University of California san francisco
Co-authored papers 1
Kelsey M Haas
J. David Gladstone Institutes
Co-authored papers 1
Harmit S Malik
Fred Hutchinson Cancer Center
Co-authored papers 1
Michael B Winter
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Release 1.2