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Author Details

Nalini Raghavachari
Division of Geriatrics & Clinical Gerontology, National Institute on Aging
1996
67
34
PMIDPaper TitleJournal TitlePublished Year
35279027Optimizing Translational Research for Exceptional Health and Life Span: A Systematic Narrative of Studies to Identify Translatable Therapeutic Target(s) for Exceptional Health Span in Humans.J Gerontol A Biol Sci Med Sci2022
35821803Clonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in Humans.Front Aging2022
32789475The Impact of Apolipoprotein E Genetic Variability in Health and Life Span.J Gerontol A Biol Sci Med Sci2020
33733101Artificial Intelligence Based Approaches to Identify Molecular Determinants of Exceptional Health and Life Span-An Interdisciplinary Workshop at the National Institute on Aging.Front Artif Intell2019
29767355Overview of Gene Expression Analysis: Transcriptomics.Methods Mol Biol2018
30374935Report: NIA workshop on translating genetic variants associated with longevity into drug targets.Geroscience2018
30412599The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study.PLoS One2018
28122634Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.Genome Biol2017
26930295Genetic landscape of APOE in human longevity revealed by high-throughput sequencing.Mech Ageing Dev2016
27447179Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study.Biogerontology2016
25378535Iron, inflammation, and early death in adults with sickle cell disease.Circ Res2015
25882670Integrative network analysis reveals molecular mechanisms of blood pressure regulation.Mol Syst Biol2015
25785607A meta-analysis of gene expression signatures of blood pressure and hypertension.PLoS Genet2015
23863881No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.Mol Ther2014
25062624Gene expression profiling of hematopoietic stem cells (HSCs).Methods Mol Biol2014
25150835Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study.Nat Biotechnol2014
24733846The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses.J Immunol2014
24916507Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor.Blood2014
24139908Integrated analysis of miRNA and mRNA during differentiation of human CD34+ cells delineates the regulatory roles of microRNA in hematopoiesis.Exp Hematol2014
23539213A systems biology framework identifies molecular underpinnings of coronary heart disease.Arterioscler Thromb Vasc Biol2013
23912982Microarray technology: basic methodology and application in clinical research for biomarker discovery in vascular diseases.Methods Mol Biol2013
23632416miR-222 contributes to sex-dimorphic cardiac eNOS expression via ets-1.Physiol Genomics2013
23593351Expression of regulatory platelet microRNAs in patients with sickle cell disease.PLoS One2013
23702660Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.Arterioscler Thromb Vasc Biol2013
23766131A role for phosphodiesterase 3B in acquisition of brown fat characteristics by white adipose tissue in male mice.Endocrinology2013
23554273Imaging flow cytometry for morphologic and phenotypic characterization of rare circulating endothelial cells.Cytometry B Clin Cytom2013
23539218Gene expression signatures of coronary heart disease.Arterioscler Thromb Vasc Biol2013
22045913Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study.Physiol Genomics2012
22747986A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease.BMC Med Genomics2012
22518031Nuclear miRNA regulates the mitochondrial genome in the heart.Circ Res2012
22679008A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease.Am J Respir Crit Care Med2012
20956803Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation.Blood2011
21828245Transcriptome profiling and sequencing of differentiated human hematopoietic stem cells reveal lineage-specific expression and alternative splicing of genes.Physiol Genomics2011
21712452Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma.Clin Cancer Res2011
21374652High fat diet reduces the expression of glutathione peroxidase 3 in mouse prostate.Prostate2011
21235297Transcriptional profiling of CD133(+) cells in coronary artery disease and effects of exercise on gene expression.Cytotherapy2011
20940416The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia.Blood2011
19834966CD146+ T lymphocytes are increased in both the peripheral circulation and in the synovial effusions of patients with various musculoskeletal diseases and display pro-inflammatory gene profiles.Cytometry B Clin Cytom2010
21099356Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice.Cell Cycle2010
20806079MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide.Mol Vis2010
20890043Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors.J Clin Invest2010
20622028Apolipoprotein E negatively regulates house dust mite-induced asthma via a low-density lipoprotein receptor-mediated pathway.Am J Respir Crit Care Med2010
19679885Phenotypic and functional characterization of a mouse model of targeted Pig-a deletion in hematopoietic cells.Haematologica2010
19092138Microarray-based characterization of a colony assay used to investigate endothelial progenitor cells and relevance to endothelial function in humans.Arterioscler Thromb Vasc Biol2009
19649296Characterization of whole blood gene expression profiles as a sequel to globin mRNA reduction in patients with sickle cell disease.PLoS One2009
19578071Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction.Cardiovasc Res2009
19464364Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response.Free Radic Biol Med2009
18250226Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro.Blood2008
18579525PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle.J Biol Chem2008
17353439Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.Circulation2007
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University of Maryland School of Medicine
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Center for Sickle Cell Disease, Howard University College of Medicine
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Clinical Center/Critical Care Medicine Department, National Institutes of Health
Co-authored papers 3
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Vanderbilt University Medical Center
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and Blood Institute, National Institutes of Health
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Vanderbilt University Medical Center
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National Cancer Institute, National Institutes of Health
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Pyeongtak University
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