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Author Details

Yassen Assenov
German Cancer Research Center (DKFZ)
2006
49
29
PMIDPaper TitleJournal TitlePublished Year
36305646DNA methylation biomarkers for noninvasive detection of triple-negative breast cancer using liquid biopsy.Int J Cancer2023
36939901Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure.Basic Res Cardiol2023
33468537Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis.Gut2022
35585141Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution.Leukemia2022
36142605Identification of <i>NHLRC1</i> as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS).Int J Mol Sci2022
34415821Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in <i>PKP3</i> in lung epithelial cells.Epigenetics2022
32540173Immunotyping of clinically divergent p.Phe508del homozygous monozygous cystic fibrosis twins.J Cyst Fibros2021
33100132AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays.Epigenetics2021
32272161Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.J Thorac Oncol2020
32188505Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.Genome Med2020
30581079Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells.Cell Stem Cell2019
31640781Random forest-based modelling to detect biomarkers for prostate cancer progression.Clin Epigenetics2019
31053176DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer.Clin Epigenetics2019
31131878Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target.Int J Cancer2019
30871603RnBeads 2.0: comprehensive analysis of DNA methylation data.Genome Biol2019
30615206Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.Hepatology2019
29329372Enrichment analysis with EpiAnnotator.Bioinformatics2018
30341162Maftools: efficient and comprehensive analysis of somatic variants in cancer.Genome Res2018
30537516Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.Cancer Cell2018
30389682PDX models recapitulate the genetic and epigenetic landscape of pediatric T-cell leukemia.EMBO Mol Med2018
29633898Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors.Cell Cycle2018
29366906Intratumor heterogeneity in epigenetic patterns.Semin Cancer Biol2018
28604729DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.Nat Genet2017
28392221Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response.Stem Cell Reports2017
29109526Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability.Nat Commun2017
29259247RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.Nat Commun2017
29074949Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.Nat Genet2017
28822795Strategies for analyzing bisulfite sequencing data.J Biotechnol2017
28898234Circulating cytokines and small molecules follow distinct expression patterns in acute myeloid leukaemia.Br J Cancer2017
28713819Differential Analysis of Genetic, Epigenetic, and Cytogenetic Abnormalities in AML.Int J Genomics2017
26964756Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis.Nat Commun2016
27575023Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis.Lancet Oncol2016
26780610DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia.Nat Genet2016
26121086Mutational dynamics between primary and relapse neuroblastomas.Nat Genet2015
26294725Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.Haematologica2015
24356097Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.Cancer Discov2014
25262207Comprehensive analysis of DNA methylation data with RnBeads.Nat Methods2014
25066126Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.Cell Rep2014
24081945A prognostic DNA methylation signature for stage I non-small-cell lung cancer.J Clin Oncol2013
21613409A DNA methylation fingerprint of 1628 human samples.Genome Res2012
23079744Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues.Epigenetics2012
22422314Topological analysis and interactive visualization of biological networks and protein structures.Nat Protoc2012
22399470Analyzing epigenome data in context of genome evolution and human diseases.Methods Mol Biol2012
21911366A promoter DNA demethylation landscape of human hematopoietic differentiation.Nucleic Acids Res2012
18006545Computing topological parameters of biological networks.Bioinformatics2008
17372197The implications of alternative splicing in the ENCODE protein complement.Proc Natl Acad Sci U S A2007
17647236Computational analysis of human protein interaction networks.Proteomics2007
17276992A network-based analysis of polyanion-binding proteins utilizing human protein arrays.J Biol Chem2007
16982674A network-based analysis of polyanion-binding proteins utilizing yeast protein arrays.Mol Cell Proteomics2006
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Collaborators

Christoph Plass
German Cancer Research Center
Co-authored papers 25
Dieter Weichenhan
German Cancer Research Center (DKFZ)
Co-authored papers 10
Clarissa Gerh??user
German Cancer Research Center (DKFZ)
Co-authored papers 7
Reka Toth
German Cancer Research Center (DKFZ)
Co-authored papers 7
Christoph Bock
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 7
Olga Bogatyrova
German Cancer Research Center
Co-authored papers 6
Mario Albrecht
Institute for Knowledge Discovery, Graz University of Technology
Co-authored papers 6
Pavlo Lutsik
Catholic University (KU) Leuven
Co-authored papers 6
Benedikt Brors
German Cancer Research Center (DKFZ)
Co-authored papers 6
Jan O Korbel
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 5
Angela Risch
Allergy-Cancer-BioNano Research Centre, University of Salzburg
Co-authored papers 4
Peter Schirmacher
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 3
Andreas E Kulozik
Co-authored papers 3
Thorsten Schlomm
Charite - University Hospital Berlin
Co-authored papers 3
Tobias Rausch
University of Heidelberg
Co-authored papers 3
Olaf Witt
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 3
Fidel Ram??rez
Max Planck Institute of Immunobiology and Epigenetics
Co-authored papers 3
Renate Kirschner-Schwabe
Co-authored papers 3
Guido Sauter
Institute of Pathology, University Medical Center Hamburg-Eppendorf
Co-authored papers 3
Cornelia Eckert
Co-authored papers 3
Ronald Simon
Institute of Pathology, University Medical Center Hamburg-Eppendorf
Co-authored papers 3
Joachim Weischenfeldt
University of Copenhagen
Co-authored papers 3
Matthias Schlesner
University of Augsburg
Co-authored papers 3
Lars Feuerbach
German Cancer Research Center (DKFZ)
Co-authored papers 3
Thomas J Kipps
University of California San Diego
Co-authored papers 2
Jens Langstein
German Cancer Research Center (DKFZ) & National Center for Tumor Diseases (NCT)
Co-authored papers 2
Claudia Hube-Magg
Institute of Pathology, University Medical Center Hamburg-Eppendorf
Co-authored papers 2
Jaume Mora
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
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Jörn Walter
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Release 1.2