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Author Details
Full Name
Mark A Le Gros
Affiliation
University of California San Francisco
ORCID
Career Start Year
2001
Papers
51
H Index
27
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36519968
Soft X-ray tomograms provide a structural basis for whole-cell modeling.
FASEB J
2023
37613514
Soft X-ray 3D Imaging: A Powerful Tool for Visualizing Virus Infections with Increased Resolution and Field of View.
Microsc Microanal
2023
37613471
Soft X-ray 3D imaging: A Powerful Tool for Visualizing Virus Infections with Increased Resolution and Field of View.
Microsc Microanal
2023
37613169
The Role of Soft X-ray Tomography in Generating Whole-cell Models.
Microsc Microanal
2023
37081164
Nuclear and cytoplasmic spatial protein quality control is coordinated by nuclear-vacuolar junctions and perinuclear ESCRT.
Nat Cell Biol
2023
35199039
A protocol for full-rotation soft X-ray tomography of single cells.
STAR Protoc
2022
36560654
Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells.
Viruses
2022
35148829
Soft X-ray tomography to map and quantify organelle interactions at the mesoscale.
Structure
2022
34729550
Using soft X-ray tomography for rapid whole-cell quantitative imaging of SARS-CoV-2-infected cells.
Cell Rep Methods
2021
33196636
Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus.
PLoS Comput Biol
2020
31978064
Switchable resolution in soft x-ray tomography of single cells.
PLoS One
2020
30952801
Imaging cell morphology and physiology using X-rays.
Biochem Soc Trans
2019
29908247
PSF correction in soft X-ray tomography.
J Struct Biol
2018
27690365
Mesoscale imaging with cryo-light and X-rays: Larger than molecular machines, smaller than a cell.
Biol Cell
2017
28394250
AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation.
Elife
2017
26951677
Population-based 3D genome structure analysis reveals driving forces in spatial genome organization.
Proc Natl Acad Sci U S A
2016
27851973
Soft X-Ray Tomography Reveals Gradual Chromatin Compaction and Reorganization during Neurogenesis In Vivo.
Cell Rep
2016
25602704
Imaging and characterizing cells using tomography.
Arch Biochem Biophys
2015
26101352
Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells.
J Cell Sci
2015
23966233
Putting molecules in their place.
J Cell Biochem
2014
25418180
Quantitatively imaging chromosomes by correlated cryo-fluorescence and soft x-ray tomographies.
Biophys J
2014
25343808
Biological soft X-ray tomography on beamline 2.1 at the Advanced Light Source.
J Synchrotron Radiat
2014
24355261
Correlative cryogenic tomography of cells using light and soft x-rays.
Ultramicroscopy
2014
23086890
Nanoimaging cells using soft X-ray tomography.
Methods Mol Biol
2013
23955281
The influence of spatial variation in chromatin density determined by X-ray tomograms on the time to find DNA binding sites.
Bull Math Biol
2013
23531637
Correlative microscopy methods that maximize specimen fidelity and data completeness, and improve molecular localization capabilities.
J Struct Biol
2013
21945653
Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum.
J Struct Biol
2012
23029546
Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator.
PLoS One
2012
23141535
Nuclear aggregation of olfactory receptor genes governs their monogenic expression.
Cell
2012
22650370
Fluorescence-detected X-ray magnetic circular dichroism of well-defined Mn(II) and Ni(II) doped in MgO crystals: credential evaluation for measurements on biological samples.
J Phys Chem A
2012
22242730
Visualizing cell architecture and molecular location using soft x-ray tomography and correlated cryo-light microscopy.
Annu Rev Phys Chem
2012
22290620
Visualizing and quantifying cell phenotype using soft X-ray tomography.
Bioessays
2012
22155289
Automatic alignment and reconstruction of images for soft X-ray tomography.
J Struct Biol
2012
20826218
Cryo transmission X-ray imaging of the malaria parasite, P. falciparum.
J Struct Biol
2011
21360734
Quantitative analysis of yeast internal architecture using soft X-ray tomography.
Yeast
2011
19566622
High-aperture cryogenic light microscopy.
J Microsc
2009
19880740
Soft X-ray tomography of phenotypic switching and the cellular response to antifungal peptoids in Candida albicans.
Proc Natl Acad Sci U S A
2009
19818625
Soft X-ray tomography and cryogenic light microscopy: the cool combination in cellular imaging.
Trends Cell Biol
2009
18387313
Quantitative 3-D imaging of eukaryotic cells using soft X-ray tomography.
J Struct Biol
2008
18491018
TiO2 nanoparticles as a soft X-ray molecular probe.
Chem Commun (Camb)
2008
17212460
Semiconductor quantum rods as single molecule fluorescent biological labels.
Nano Lett
2007
17376659
The maternally localized RNA fatvg is required for cortical rotation and germ cell formation.
Mech Dev
2007
17459084
X-ray tomography of Schizosaccharomyces pombe.
Differentiation
2007
17237535
Measuring cell motility using quantum dot probes.
Methods Mol Biol
2007
15985641
Quantum-dot-based cell motility assay.
Sci STKE
2005
16153818
X-ray tomography of whole cells.
Curr Opin Struct Biol
2005
14699066
X-ray tomography generates 3-D reconstructions of the yeast, saccharomyces cerevisiae, at 60-nm resolution.
Mol Biol Cell
2004
12518059
Imaging whole Escherichia coli bacteria by using single-particle x-ray diffraction.
Proc Natl Acad Sci U S A
2003
12969334
Actin-filled nuclear invaginations indicate degree of cell de-differentiation.
Differentiation
2003
14686951
Quantum dot-based cell motility assay.
Differentiation
2003
1 - 50 of 51
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Massachusetts Institute of Technology
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David Geffen School of Medicine, University of California at Los Angeles
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