Author details

Full Name

Yi-Shuan Li

Affiliation

ORCID

Career Start Year

1990

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36603156	Vascular mechanotransduction.	Physiol Rev	2023
34810252	Vitexin inhibits APEX1 to counteract the flow-induced endothelial inflammation.	Proc Natl Acad Sci U S A	2021
33898431	Maintenance of HDACs and H3K9me3 Prevents Arterial Flow-Induced Venous Endothelial Damage.	Front Cell Dev Biol	2021
32076643	Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458.	Sci Adv	2020
30884320	MiR-145 mediates cell morphology-regulated mesenchymal stem cell differentiation to smooth muscle cells.	Biomaterials	2019
31650299	A Lifetime Achievement in Bioengineering: Professor Shu Chien.		2019
31597449	Extracellular MicroRNA-92a Mediates Endothelial Cell-Macrophage Communication.	Arterioscler Thromb Vasc Biol	2019
30088112	Fine control of endothelial VEGFR-2 activation: caveolae as fluid shear stress shelters for membrane receptors.	Biomech Model Mechanobiol	2019
31182601	Shear stress regulation of miR-93 and miR-484 maturation through nucleolin.	Proc Natl Acad Sci U S A	2019
29255056	Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis.	Proc Natl Acad Sci U S A	2018
30478057	Coordinated histone modifications and chromatin reorganization in a single cell revealed by FRET biosensors.	Proc Natl Acad Sci U S A	2018
29118325	The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow.	Sci Rep	2017
28500253	LINC00341 exerts an anti-inflammatory effect on endothelial cells by repressing VCAM1.	Physiol Genomics	2017
28716920	VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia.	Proc Natl Acad Sci U S A	2017
27671657	Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis.	Proc Natl Acad Sci U S A	2016
26915560	Role of Excessive Autophagy Induced by Mechanical Overload in Vein Graft Neointima Formation: Prediction and Prevention.	Sci Rep	2016
26858399	Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting.	Proc Natl Acad Sci U S A	2016
27841276	Corrigendum: Role of Excessive Autophagy Induced by Mechanical Overload in Vein Graft Neointima Formation: Prediction and Prevention.	Sci Rep	2016
25446515	Rapid identification of HPV 16 and 18 by multiplex nested PCR-immunochromatographic test.	Journal of Virological Methods	2015
25712942	Endothelial trauma from mechanical thrombectomy in acute stroke: in vitro live-cell platform with animal validation.	Stroke	2015
24685572	Comparison of KRAS mutation analysis of primary tumors and matched circulating cell-free DNA in plasmas of patients with colorectal cancer.	Clinica Chimica Acta	2014
24855060	MicroRNA-23b regulates cyclin-dependent kinase-activating kinase complex through cyclin H repression to modulate endothelial transcription and growth under flow.	Arterioscler Thromb Vasc Biol	2014
24883126	Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1.	Cell Mol Bioeng	2014
24958852	Piezo1, a mechanically activated ion channel, is required for vascular development in mice.	Proc Natl Acad Sci U S A	2014
24876354	Shear stress-initiated signaling and its regulation of endothelial function.	Arterioscler Thromb Vasc Biol	2014
23603512	Regulation of vascular smooth muscle cell turnover by endothelial cell-secreted microRNA-126: role of shear stress.	Circ Res	2013
23967196	Human mesenchymal stem cells suppress the stretch-induced inflammatory miR-155 and cytokines in bronchial epithelial cells.	PLoS One	2013
23878263	Shear stress activation of nuclear receptor PXR in endothelial detoxification.	Proc Natl Acad Sci U S A	2013
23118862	Matrix stiffness regulates endothelial cell proliferation through septin 9.	PLoS One	2012
22665785	Roles of cell confluency and fluid shear in 3-dimensional intracellular forces in endothelial cells.	Proc Natl Acad Sci U S A	2012
21768538	Flow-Dependent Regulation of Kruppel-Like Factor 2 Is Mediated by MicroRNA-92a.	Circulation	2011
20415587	microRNA: a master regulator of cellular processes for bioengineering systems.	Annu Rev Biomed Eng	2010
20133741	Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth.	Proc Natl Acad Sci U S A	2010
20133739	MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells.	Proc Natl Acad Sci U S A	2010
20479254	Shear stress, SIRT1, and vascular homeostasis.	Proc Natl Acad Sci U S A	2010
19889638	Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.	J Biol Chem	2010
20011623	Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-ÎºB Pathway Via Actin and Tyrosine Kinases.	Cell Mol Bioeng	2009
19692650	Focal adhesion kinase phosphorylation in flow-activation of endothelial NF-kappaB. Focus on "Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells".	Am J Physiol Cell Physiol	2009
19179282	Stem cell fate dictated solely by altered nanotube dimension.	Proc Natl Acad Sci U S A	2009
19416856	Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow.	Proc Natl Acad Sci U S A	2009
19799797	Difference in the regulation of IL-8 expression induced by uropathogenic E. coli between two kinds of urinary tract epithelial cells.	Journal of Biomedical Science	2009
19779633	Live Cells Exert 3-Dimensional Traction Forces on Their Substrata.	Cell Mol Bioeng	2009
18840694	Anisotropic rheology and directional mechanotransduction in vascular endothelial cells.	Proc Natl Acad Sci U S A	2008
16867303	Molecular basis of the effects of mechanical stretch on vascular smooth muscle cells.	J Biomech	2007
17229844	Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry.	Proc Natl Acad Sci U S A	2007
16328952	DNA microarray study on gene expression profiles in co-cultured endothelial and smooth muscle cells in response to 4- and 24-h shear stress.	Mol Cell Biochem	2006
16466697	Shear stress regulation of KrÃ¼ppel-like factor 2 expression is flow pattern-specific.	Biochem Biophys Res Commun	2006
16920067	Roles of microfilaments and microtubules in paxillin dynamics.	Biochem Biophys Res Commun	2006
16440309	Roles of MAP kinases in the regulation of bone matrix gene expressions in human osteoblasts by oscillatory fluid flow.	J Cell Biochem	2006
16477012	Synergistic roles of platelet-derived growth factor-BB and interleukin-1beta in phenotypic modulation of human aortic smooth muscle cells.	Proc Natl Acad Sci U S A	2006