Author details

Full Name

James U Bowie

Affiliation

ORCID

Career Start Year

1983

Papers

162

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35133709	How physical forces drive the process of helical membrane protein folding.	EMBO Reports	2022
35690147	Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways.	Journal of Biological Chemistry	2022
35546163	Expanding the use of ethanol as a feedstock for cell-free synthetic biochemistry by implementing acetyl-CoA and ATP generating pathways.	Scientific Reports	2022
33941811	Cell-free synthetic biochemistry upgrading of ethanol to 1,3 butanediol.	Scientific Reports	2021
32839605	A bio-inspired cell-free system for cannabinoid production from inexpensive inputs.	Nature Chemical Biology	2020
31983463	Synthetic Biochemistry: The Bio-inspired Cell-Free Approach to Commodity Chemical Production.	Trends in Biotechnology	2020
32855421	Isobutanol production freed from biological limits using synthetic biochemistry.	Nature Communications	2020
33058341	How bilayer properties influence membrane protein folding.	Protein Science	2020
30718485	A cell-free platform for the prenylation of natural products and application to cannabinoid production.	Nat Commun	2019
31780561	Watching helical membrane proteins fold reveals a common N-to-C-terminal folding pathway.	Science	2019
31127097	Author Correction: A cell-free platform for the prenylation of natural products and application to cannabinoid production.	Nat Commun	2019
29496880	Accurate computational design of multipass transmembrane proteins.	Science	2018
28549924	Applications of Single-Molecule Methods to Membrane Protein Folding Studies.	Journal of Molecular Biology	2018
29290488	Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.	Structure	2018
29581582	Unfolding of a ClC chloride transporter retains memory of its evolutionary history.	Nature Chemical Biology	2018
28168866	Complete topology inversion can be part of normal membrane protein biogenesis.	Protein Science	2017
28692798	Backbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices.	Journal of the American Chemical Society	2017
28671683	A molecular rheostat maintains ATP levels to drive a synthetic biochemistry system.	Nature Chemical Biology	2017
28537253	A synthetic biochemistry platform for cell free production of monoterpenes from glucose.	Nature Communications	2017
28004831	An Adaptation To Life In Acid Through A Novel Mevalonate Pathway.	Scientific Reports	2016
27065234	A synthetic biochemistry module for production of bio-based chemicals from glucose.	Nature Chemical Biology	2016
26755636	Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.	Genome Res	2016
27053100	Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme.	Scientific Reports	2016
27222403	A simple DNA handle attachment method for single molecule mechanical manipulation experiments.	Protein Science	2016
26679426	Molecular dynamics simulation strategies for protein-micelle complexes.		2016
26306475	Dual-topology insertion of a dual-topology membrane protein.	Nature Communications	2015
25923201	Metazoans evolved by taking domains from soluble proteins to expand intercellular communication network.	Scientific Reports	2015
25422158	Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases.	Protein Science	2015
26479439	Mapping the energy landscape for second-stage folding of a single membrane protein.	Nature Chemical Biology	2015
24998259	Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.	BMC Structural Biology	2014
25369295	Bacteriorhodopsin folds through a poorly organized transition state.	Journal of the American Chemical Society	2014
24501090	An energetic scale for equilibrium H/D fractionation factors illuminates hydrogen bond free energies in proteins.	Protein Science	2014
24367094	Measuring membrane protein stability under native conditions.	Proceedings of the National Academy of Sciences of the United States of America	2014
24914732	Evidence of a novel mevalonate pathway in archaea.	Biochemistry	2014
24623472	A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates.	Protein Sci	2014
24936528	A synthetic biochemistry molecular purge valve module that maintains redox balance.	Nature Communications	2014
24932721	Improving the tolerance of Escherichia coli to medium-chain fatty acid production.	Metabolic Engineering	2014
23555228	Rampant exchange of the structure and function of extramembrane domains between membrane and water soluble proteins.	PLoS Computational Biology	2013
24032628	Membrane proteins can have high kinetic stability.	Journal of the American Chemical Society	2013
23975771	Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping.	Methods in Molecular Biology	2013
23648063	Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution.	Biotechnology for Biofuels	2013
23349275	Structural biology. Membrane protein twists and turns.	Science	2013
22095725	Revisiting the folding kinetics of bacteriorhodopsin.	Protein Science	2012
22566663	Shifting hydrogen bonds may produce flexible transmembrane helices.	Proceedings of the National Academy of Sciences of the United States of America	2012
23001966	Structural differences between thermophilic and mesophilic membrane proteins.	Protein Science	2012
23198090	Network rewiring is an important mechanism of gene essentiality change.	Scientific Reports	2012
23300806	Crystal structure of Proteus mirabilis lipase, a novel lipase from the Proteus/psychrophilic subfamily of lipase family I.1.	PLoS ONE	2012
21880269	Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state.		2012
21982781	Crystallizing membrane proteins using lipidic bicelles.	Methods	2011
21217644	Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation.	EMBO Journal	2011