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Author Details

Carlos J Camacho
University of Pittsburgh
1990
105
37
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37311034Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein.Sci Signal2023
37549772Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.SLAS Discov2023
37311034Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein.Sci Signal2023
37549772Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.SLAS Discov2023
36187353More than a marker: potential pathogenic functions of MAP2.Front Mol Neurosci2022
35762422A heterotypic assembly mechanism regulates CHIP E3 ligase activity.EMBO J2022
36027913A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing.Mol Cell2022
36206451Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors.J Med Chem2022
36187353More than a marker: potential pathogenic functions of MAP2.Front Mol Neurosci2022
35762422A heterotypic assembly mechanism regulates CHIP E3 ligase activity.EMBO J2022
36206451Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors.J Med Chem2022
36027913A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing.Mol Cell2022
34228644Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma.J Clin Invest2021
34228644Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma.J Clin Invest2021
33522796Tripeptide IRW Upregulates NAMPT Protein Levels in Cells and Obese C57BL/6J Mice.J Agric Food Chem2021
34262016Novel FOXM1 inhibitor identified via gene network analysis induces autophagic FOXM1 degradation to overcome chemoresistance of human cancer cells.Cell Death Dis2021
34522857A resource of high-quality and versatile nanobodies for drug delivery.iScience2021
34934174A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.Commun Biol2021
33522796Tripeptide IRW Upregulates NAMPT Protein Levels in Cells and Obese C57BL/6J Mice.J Agric Food Chem2021
34934174A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.Commun Biol2021
34522857A resource of high-quality and versatile nanobodies for drug delivery.iScience2021
34262016Novel FOXM1 inhibitor identified via gene network analysis induces autophagic FOXM1 degradation to overcome chemoresistance of human cancer cells.Cell Death Dis2021
32187447Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach.ChemMedChem2020
32187447Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach.ChemMedChem2020
31721338Cross-docking benchmark for automated pose and ranking prediction of ligand binding.Protein Sci2020
32034123De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences.Nat Commun2020
32766592On the molecular mechanism of SARS-CoV-2 retention in the upper respiratory tract.bioRxiv2020
31721338Cross-docking benchmark for automated pose and ranking prediction of ligand binding.Protein Sci2020
32034123De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences.Nat Commun2020
32766592On the molecular mechanism of SARS-CoV-2 retention in the upper respiratory tract.bioRxiv2020
30478172Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells.J Biol Chem2019
31850311Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck.Front Chem2019
31664084Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations.Sci Rep2019
30478172Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells.J Biol Chem2019
31029767Transcription with a laser: Radiation-damage-free diffraction of RNA Polymerase II crystals.Methods2019
30808860A network-centric approach to drugging TNF-induced NF-κB signaling.Nat Commun2019
30897521NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow.Redox Biol2019
31308225Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant.Proc Natl Acad Sci U S A2019
31664084Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations.Sci Rep2019
31850311Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck.Front Chem2019
31308225Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant.Proc Natl Acad Sci U S A2019
30897521NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow.Redox Biol2019
30808860A network-centric approach to drugging TNF-induced NF-κB signaling.Nat Commun2019
31029767Transcription with a laser: Radiation-damage-free diffraction of RNA Polymerase II crystals.Methods2019
28918599Optimal affinity ranking for automated virtual screening validated in prospective D3R grand challenges.J Comput Aided Mol Des2018
28918599Optimal affinity ranking for automated virtual screening validated in prospective D3R grand challenges.J Comput Aided Mol Des2018
28921842AnchorQuery: Rapid online virtual screening for small-molecule protein-protein interaction inhibitors.Protein Sci2018
30355733A combined computational and experimental approach reveals the structure of a C/EBPβ-Spi1 interaction required for <i>IL1B</i> gene transcription.J Biol Chem2018
29920436Improving small molecule virtual screening strategies for the next generation of therapeutics.Curr Opin Chem Biol2018
30532261Predicting protein targets for drug-like compounds using transcriptomics.PLoS Comput Biol2018
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Collaborators

Sandor Vajda
Boston University
Co-authored papers 16
David W Gatchell
Co-authored papers 4
Charles DeLisi
Co-authored papers 3
Apeng Chen
Co-authored papers 2
Kristina De Paris
University of North Carolina at Chapel Hill Chapel Hill
Co-authored papers 2
Baoli Hu
Co-authored papers 2
Zhiping Weng
University of Massachusetts Medical School
Co-authored papers 2
Shoshana J Wodak
VIB-VUB Center for Structural Biology
Co-authored papers 1
Camden M Driggers
Co-authored papers 1
Yaoqi Zhou
Co-authored papers 1
Panagiotis L Kastritis
Interdisciplinary Research Center HALOmem, Martin Luther University Halle-Wittenberg
Co-authored papers 1
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 1
Masahito Ohue
Co-authored papers 1
Raed Khashan
Co-authored papers 1
Robert A Sweet
University of Pittsburgh
Co-authored papers 1
Bin Liu
Co-authored papers 1
Ron Jacak
Co-authored papers 1
Allyson F O'Donnell
University of Pittsburgh
Co-authored papers 1
Omar Demerdash
Co-authored papers 1
Jérôme Azé
Co-authored papers 1
Aoife McLysaght
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 1
Seren Soner
Co-authored papers 1
John J Stegeman
Woods Hole Oceanographic Institution
Co-authored papers 1
Ora Schueler-Furman
Co-authored papers 1
Dandan Sun
Co-authored papers 1
Itai Yanai
Institute for Systems Genetics NYU Grossman School of Medicine
Co-authored papers 1
Charles H Robert
Co-authored papers 1
Shiyong Liu
Co-authored papers 1
Aroop Sircar
Co-authored papers 1
Nelson C Coelho
University of Pittsburgh, USA Pittsburgh Center for Evolutionary Biology and Medicine
Co-authored papers 1
Release 1.2