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Author Details
Full Name
Jan St??hr
Affiliation
Weill Institute for Neurosciences, University of California san francisco
ORCID
Career Start Year
2005
Papers
31
H Index
20
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36824886
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models.
bioRxiv
2023
36809847
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Neurobiol Dis
2023
29319162
A long-lived Aβ oligomer resistant to fibrillization.
Biopolymers
2018
29311311
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.
Proc Natl Acad Sci U S A
2018
28003279
Structural Biology of PrP Prions.
Cold Spring Harb Perspect Med
2017
28837163
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
Nat Chem
2017
28566494
Zinc-binding structure of a catalytic amyloid from solid-state NMR.
Proc Natl Acad Sci U S A
2017
27414264
Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study.
J Am Chem Soc
2016
25809267
Structural studies of truncated forms of the prion protein PrP.
Biophys J
2015
26325658
Truncated forms of the prion protein PrP demonstrate the need for complexity in prion structure.
Prion
2015
26287631
Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering.
Biophys J
2015
26286986
Propagation of prions causing synucleinopathies in cultured cells.
Proc Natl Acad Sci U S A
2015
25695325
Mechanism of scrapie prion precipitation with phosphotungstate anions.
ACS Chem Biol
2015
24651196
Short peptides self-assemble to produce catalytic amyloids.
Nat Chem
2014
24982139
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients.
Proc Natl Acad Sci U S A
2014
24982137
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.
Proc Natl Acad Sci U S A
2014
23977331
Seeded fibrillation as molecular basis of the species barrier in human prion diseases.
PLoS One
2013
22331873
Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.
Proc Natl Acad Sci U S A
2012
23225001
Prion protein aggregation and fibrillogenesis in vitro.
Subcell Biochem
2012
22711819
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions.
Proc Natl Acad Sci U S A
2012
22677387
Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold.
Biophys J
2012
21476870
In vitro conversion and seeded fibrillization of posttranslationally modified prion protein.
Biol Chem
2011
22163178
Protease-resistant prions selectively decrease Shadoo protein.
PLoS Pathog
2011
22160704
Spontaneous generation of anchorless prions in transgenic mice.
Proc Natl Acad Sci U S A
2011
21151607
Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitro.
PLoS One
2010
18341429
Aggregation and amyloid fibril formation of the prion protein is accelerated in the presence of glycogen.
Rejuvenation Res
2008
18585368
Spontaneous and BSE-prion-seeded amyloid formation of full length recombinant bovine prion protein.
Biochem Biophys Res Commun
2008
18669653
Structural changes of membrane-anchored native PrP(C).
Proc Natl Acad Sci U S A
2008
18252750
Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide.
Protein Eng Des Sel
2008
18268326
Mechanisms of prion protein assembly into amyloid.
Proc Natl Acad Sci U S A
2008
16006244
Assembly of natural and recombinant prion protein into fibrils.
Biol Chem
2005
1 - 31 of 31
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Sumita Bhardwaj
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