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Author Details

Roscoe O Brady
McLean Hospital
1948
546
101
PMIDPaper TitleJournal TitlePublished Year
33183362Functional connectivity associated with improvement in emotion management after cognitive enhancement therapy in early-course schizophrenia.Psychol Med2022
35709648Dynamic intervention-based biomarkers may reduce heterogeneity and motivate targeted interventions in clinical high risk for psychosis.Schizophr Res2022
35222123Noninvasive Brain Stimulation for Nicotine Dependence in Schizophrenia: A Mini Review.Front Psychiatry2022
35153877Evidence for Schizophrenia-Specific Pathophysiology of Nicotine Dependence.Front Psychiatry2022
34697450Dynamic and progressive changes in thalamic functional connectivity over the first five years of psychosis.Mol Psychiatry2022
32583570Altered cerebral perfusion in bipolar disorder: A pCASL MRI study.Bipolar Disord2021
33882534Bridging the Gap: Strategies to Make Psychiatric Neuroimaging Clinically Relevant.Harv Rev Psychiatry2021
34911197Auditory hallucinations across the psychosis spectrum: Evidence of dysconnectivity involving cerebellar and temporal lobe regions.Neuroimage Clin2021
34789878Reverse-translational identification of a cerebellar satiation network.Nature2021
34653740Intermittent theta burst stimulation of cerebellar vermis enhances fronto-cerebellar resting state functional connectivity in schizophrenia with predominant negative symptoms: A randomized controlled trial.Schizophr Res2021
32572485Heterogeneity of Outcomes and Network Connectivity in Early-Stage Psychosis: A Longitudinal Study.Schizophr Bull2021
32648915Individual Variation in Functional Brain Network Topography is Linked to Schizophrenia Symptomatology.Schizophr Bull2021
30651603Correction: Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness.Mol Psychiatry2020
33329111Cerebellar-Cortical Connectivity Is Linked to Social Cognition Trans-Diagnostically.Front Psychiatry2020
32660299Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study.Am J Psychiatry2020
32507376Do neurobiological differences exist between paranoid and non-paranoid schizophrenia? Findings from the bipolar schizophrenia network on intermediate phenotypes study.Schizophr Res2020
30696271Cerebellar-Prefrontal Network Connectivity and Negative Symptoms in Schizophrenia.Am J Psychiatry2019
30630078Individual variation in brain network topology is linked to emotional intelligence.Neuroimage2019
30340100Diverse pathophysiological processes converge on network disruption in mania.J Affect Disord2019
29232311Lithium + Colchicine: A Potential Strategy to Reduce Pro-inflammatory Effects of Lithium Treatment.J Clin Psychopharmacol2018
27744225Differential brain network activity across mood states in bipolar disorder.J Affect Disord2017
28415008Bipolar mood state reflected in cortico-amygdala resting state connectivity: A cohort and longitudinal study.J Affect Disord2017
28272132Cognitive Decline in a Case of Poorly Controlled Bipolar Disorder: A Diagnostic and Therapeutic Challenge.Harv Rev Psychiatry2017
28915577Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.Oncotarget2017
27814962Neural complexity as a potential translational biomarker for psychosis.J Affect Disord2017
26731445Absence of evidence for increase in risk for autism or attention-deficit hyperactivity disorder following antidepressant exposure during pregnancy: a replication study.Transl Psychiatry2016
27177299State dependent cortico-amygdala circuit dysfunction in bipolar disorder.J Affect Disord2016
27471012Development of a model system for neuronal dysfunction in Fabry disease.Mol Genet Metab2016
27484861Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.Stem Cells Transl Med2016
26683465A Short Synthetic Peptide Mimetic of Apolipoprotein A1 Mediates Cholesterol and Globotriaosylceramide Efflux from Fabry Fibroblasts.JIMD Rep2016
25583479Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradation.Proc Natl Acad Sci U S A2015
26525885Emergent treatments based on the pathophysiology of bipolar disorder: A selective review.Asian J Psychiatr2015
25957416Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy.Oncotarget2015
24488939Position statement: National Gaucher Foundation Medical Advisory Board, January 7, 2014.Am J Hematol2014
25088464Normalization and improvement of CNS deficits in mice with Hurler syndrome after long-term peripheral delivery of BBB-targeted iduronidase.Mol Ther2014
24550296Platelets are efficient and protective depots for storage, distribution, and delivery of lysosomal enzyme in mice with Hurler syndrome.Proc Natl Acad Sci U S A2014
24639522Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease.Proc Natl Acad Sci U S A2014
24335514Neurobiology of mood-state shifts in bipolar disorder: a selective review and a hypothesis.Harv Rev Psychiatry2014
24351928Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones.Proc Natl Acad Sci U S A2014
22814681An innovative approach to the treatment of Gaucher disease and possibly other metabolic disorders of the brain.J Inherit Metab Dis2013
23866739Are structural brain abnormalities associated with suicidal behavior in patients with psychotic disorders?J Psychiatr Res2013
2399068499mTc-sestamibi scintigraphy to monitor the long-term efficacy of enzyme replacement therapy on bone marrow infiltration in patients with Gaucher disease.J Nucl Med2013
23634979Brain gamma-aminobutyric acid (GABA) abnormalities in bipolar disorder.Bipolar Disord2013
23754423Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury.Proc Natl Acad Sci U S A2013
23382178Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier.Proc Natl Acad Sci U S A2013
23277556Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperones.Proc Natl Acad Sci U S A2013
22505738β-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas.Proc Natl Acad Sci U S A2012
22968227A longitudinal pilot proton MRS investigation of the manic and euthymic states of bipolar disorder.Transl Psychiatry2012
21379351Biomarkers in schizophrenia: we need to rebuild the Titanic.World Psychiatry2011
22160715Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease.Proc Natl Acad Sci U S A2011
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Collaborators

Zhengping Zhuang
National Cancer Institute, National Institutes of Health
Co-authored papers 11
Jeffrey A Medin
Medical College of Wisconsin
Co-authored papers 9
Bruce M Cohen
Harvard Medical School
Co-authored papers 5
Monique P Gelderman
Center for Biologics Evaluation and Research
Co-authored papers 5
Pankaj Qasba
Co-authored papers 5
Edward H Oldfield
National Institutes of Health
Co-authored papers 4
Jeffrey B Kopp
National Institutes of Health, National Institute of Diabetes
Co-authored papers 4
Godfrey D Pearlson
Yale School of Medicine, Yale University
Co-authored papers 4
Pramod K Mistry
Co-authored papers 3
Robert I Parker
Stony Brook Renaissances School of Medicine, Stony Brook University
Co-authored papers 3
Solomon H Snyder
Co-authored papers 3
Gangjian Qin
University of Alabama at Birmingham, 1670 University Boulevard
Co-authored papers 3
Karel Pacak
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Co-authored papers 2
Aaron D Robison
Loma Linda University
Co-authored papers 2
Perry F Renshaw
University of Utah
Co-authored papers 2
Eun Young Kim
College of Korean Medicine, Kyung Hee University
Co-authored papers 2
John A Hanover
Co-authored papers 2
Abdel G Elkahloun
National Human Genome Research Institute
Co-authored papers 2
Alysa E Doyle
Massachusetts General Hospital
Co-authored papers 1
Robert J Weil
Rhode Island Hospital
Co-authored papers 1
Howard L Weiner
Co-authored papers 1
Jeanette Beers
and Blood Institute, National Institutes of Health
Co-authored papers 1
Christopher K Zalewski
Co-authored papers 1
Lori J West
University of Alberta
Co-authored papers 1
Margaret A Niznikiewicz
VA Boston Healthcare System
Co-authored papers 1
Ana Maria Cuervo
Albert Einstein College of Medicine
Co-authored papers 1
Justin C McArthur
Johns Hopkins School of Medicine
Co-authored papers 1
Johan L K Van Hove
Section of Clinical Genetics and Metabolism, University of Colorado
Co-authored papers 1
Ronald C Beavis
University of Manitoba
Co-authored papers 1
Angus C Nairn
Co-authored papers 1
Release 1.2