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Author Details
Full Name
Jun Qi
Affiliation
Dana-Farber Cancer Institute
ORCID
Career Start Year
2010
Papers
132
H Index
52
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36894709
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.
Nat Genet
2023
37957169
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics.
Nat Commun
2023
37541244
Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.
Cancer Cell
2023
37637739
Manipulating Tyrosine Phosphorylation by Heterobifunctional Small Molecules.
ACS Cent Sci
2023
37075745
Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis.
Adv Sci (Weinh)
2023
37163075
Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks.
bioRxiv
2023
37461690
SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis.
bioRxiv
2023
36780189
BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma.
Clin Cancer Res
2023
36909530
BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma.
bioRxiv
2023
36824856
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders.
bioRxiv
2023
34341479
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.
Leukemia
2022
35363464
Exploring Methods of Targeting Histone Methyltransferases and Their Applications in Cancer Therapeutics.
ACS Chem Biol
2022
35681054
SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma.
Nat Genet
2022
35941525
1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains.
Arch Pharm (Weinheim)
2022
35867655
Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity.
J Med Chem
2022
36305736
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
Cancer Discov
2022
35975457
Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.
Adv Sci (Weinh)
2022
35226736
BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.
Blood
2022
35217626
A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia.
Proc Natl Acad Sci U S A
2022
34932262
Dihydropyridine Lactam Analogs Targeting BET Bromodomains.
ChemMedChem
2022
34772733
EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma.
Cancer Discov
2022
33460788
Brd4 participates in epigenetic regulation of the extinction of remote auditory fear memory.
Neurobiol Learn Mem
2021
33872011
Development of Dimethylisoxazole-Attached Imidazo[1,2-<i>a</i>]pyridines as Potent and Selective CBP/P300 Inhibitors.
J Med Chem
2021
33730585
Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma.
Cell Rep
2021
34434504
Correction: HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.
Oncotarget
2021
34593523
Targeting an Inducible SALL4-Mediated Cancer Vulnerability with Sequential Therapy.
Cancer Res
2021
34107377
The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53.
Neoplasia
2021
34037670
Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection.
J Exp Med
2021
34358447
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.
Mol Cell
2021
34258103
Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.
Blood Cancer Discov
2021
33972779
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence.
Nat Genet
2021
32559499
Peptide-Based PROTAC: The Predator of Pathological Proteins.
Cell Chem Biol
2020
31691152
BET bromodomain inhibition suppresses adipogenesis in mice.
Endocrine
2020
31744829
<i>In Vivo</i> Epigenetic CRISPR Screen Identifies <i>Asf1a</i> as an Immunotherapeutic Target in <i>Kras</i>-Mutant Lung Adenocarcinoma.
Cancer Discov
2020
32832623
Inhibition of Polo-like kinase 1 (PLK1) facilitates the elimination of HIV-1 viral reservoirs in CD4<sup>+</sup> T cells ex vivo.
Sci Adv
2020
32661245
High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening.
Nat Commun
2020
32826232
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Cancer Discov
2020
32730819
BET proteins inhibitor JQ-1 impaired the extinction of remote auditory fear memory: An effect mediated by insulin like growth factor 2.
Neuropharmacology
2020
32646968
Epigenetic CRISPR Screens Identify <i>Npm1</i> as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer.
Cancer Res
2020
32393766
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer.
Nat Commun
2020
32407673
Using Chemical Epigenetics to Target Cancer.
Mol Cell
2020
32516588
Selective Targeting of Different Bromodomains by Small Molecules.
Cancer Cell
2020
30279226
Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease.
Blood
2019
31494268
Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions.
Genomics Proteomics Bioinformatics
2019
31260717
Maintenance and enhancement of human peripheral blood mobilized stem/progenitor cell engraftment after ex vivo culture via an HDACi/SALL4 axis (3465).
Exp Hematol
2019
31285436
Chemical genomics reveals histone deacetylases are required for core regulatory transcription.
Nat Commun
2019
31395336
FRK suppresses human glioma growth by inhibiting ITGB1/FAK signaling.
Biochem Biophys Res Commun
2019
31111916
A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma.
Neuro Oncol
2019
31085176
BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models.
Cancer Cell
2019
30962579
Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma.
Leukemia
2019
1 - 50 of 132
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Kimberly Stegmaier
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Co-authored papers
11
Kenneth C Anderson
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Co-authored papers
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Harvard Medical School
Co-authored papers
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Mousheng Xu
Co-authored papers
6
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University of Parma
Co-authored papers
6
Gabriela Alexe
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5
David E Root
Broad Institute of Harvard and MIT
Co-authored papers
5
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
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4
Alexander J Federation
Co-authored papers
4
Rameen Beroukhim
Co-authored papers
4
Sheue-Yann Cheng
National Cancer Institute, National Institutes of Health
Co-authored papers
4
Scott A Armstrong
Boston Children's Hospital
Co-authored papers
4
John G Doench
Co-authored papers
4
Myles Brown
Co-authored papers
4
Pratiti Bandopadhayay
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4
Sirano Dhe-Paganon
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Co-authored papers
3
Angela Su
The Broad Institute of MIT and Harvard
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3
Stefan Knapp
Institute of Pharmaceutical Chemistry, Goethe University
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3
Alex Look
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3
Glenn S Cowley
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