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Author Details

Sheena D'Arcy
The University of Texas at Dallas
2009
32
13
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36942851Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses.Elife2023
37450495Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTPâ¿¢Kap114â¿¢H2A-H2B complex.Proc Natl Acad Sci U S A2023
37379840Molecular basis of RanGTP-activated release of Histones H2A-H2B from Importin-9.Structure2023
36747879Molecular basis of RanGTP-activated nucleosome assembly with Histones H2A-H2B bound to Importin-9.bioRxiv2023
35965017Using hydrogen-deuterium exchange mass spectrometry to characterize Mtr4 interactions with RNA.Methods Enzymol2022
35380691Hydrogen-deuterium exchange mass spectrometry of Mtr4 with diverse RNAs reveals substrate-dependent dynamics and interfaces in the arch.Nucleic Acids Res2022
35658075Leveraging intrinsic flexibility to engineer enhanced enzyme catalytic activity.Proc Natl Acad Sci U S A2022
36465553Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.Nat Catal2022
33079991HD-eXplosion: visualization of hydrogen-deuterium exchange data as chiclet and volcano plots with statistical filtering.Bioinformatics2021
34302022Identification and physical characterization of a spontaneous mutation of the tobacco mosaic virus in the laboratory environment.Sci Rep2021
34212150An activity-based fluorescent sensor for the detection of the phenol sulfotransferase SULT1A1 in living cells.RSC Chem Biol2021
32913112Stoichiometry of Rtt109 complexes with Vps75 and histones H3-H4.Life Sci Alliance2020
31988003Comprehensive analysis of histone-binding proteins with multi-angle light scattering.Methods2020
31775157FACT caught in the act of manipulating the nucleosome.Nature2020
33275413Conformational Dynamics Contribute to Substrate Selectivity and Catalysis in Human Kynureninase.ACS Chem Biol2020
33119282Proposed Allosteric Inhibitors Bind to the ATP Site of CK2α.J Med Chem2020
30521320Characterization of Caenorhabditis elegans Nucleosome Assembly Protein 1 Uncovers the Role of Acidic Tails in Histone Binding.Biochemistry2019
31589416IroT/MavN Is a <i>Legionella</i> Transmembrane Fe(II) Transporter: Metal Selectivity and Translocation Kinetics Revealed by <i>in Vitro</i> Real-Time Transport.Biochemistry2019
30855230Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.Elife2019
29787282Regulating the Uptake of Viral Nanoparticles in Macrophage and Cancer Cells via a pH Switch.Mol Pharm2018
28787574Fluorescent Functionalization across Quaternary Structure in a Virus-like Particle.Bioconjug Chem2017
28696524Molecular Hyperthermia: Spatiotemporal Protein Unfolding and Inactivation by Nanosecond Plasmonic Heating.Small2017
26884462Histone Chaperone Nap1 Is a Major Regulator of Histone H2A-H2B Dynamics at the Inducible GAL Locus.Mol Cell Biol2016
27273866Coordinated Action of Nap1 and RSC in Disassembly of Tandem Nucleosomes.Mol Cell Biol2016
26459557The right place at the right time: chaperoning core histone variants.EMBO Rep2015
23973327Chaperone Nap1 shields histone surfaces used in a nucleosome and can put H2A-H2B in an unconventional tetrameric form.Mol Cell2013
24459723Towards a mechanism for histone chaperones.Biochim Biophys Acta2013
22121211Fluorescence strategies for high-throughput quantification of protein interactions.Nucleic Acids Res2012
22023828Understanding histone acetyltransferase Rtt109 structure and function: how many chaperones does it take?Curr Opin Struct Biol2011
20220147Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition.J Biol Chem2010
19141287The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores.Structure2009
19596232A positive spin on the centromere.Cell2009
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Collaborators

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Heartand Lung Research Institute, University of Cambridge
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University of Oxford
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Columbia University
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University of Texas at Dallas
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Co-authored papers 1
UT Southwestern Medical Center
Co-authored papers 1
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Boston Children's Hospital and Dana-Farber Cancer Institute
Co-authored papers 1
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
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Texas Biomedical Research Institute
Co-authored papers 1
University of California
Co-authored papers 1
University of Cambridge, Hutchison Research Centre
Co-authored papers 1