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Author Details

Guy Sauvageau
Universite de Montreal
1988
175
53
Sami Nourreddine (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37729615CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.Blood Adv2024
36334654Bortezomib Maintenance After Allogeneic Transplantation in Newly Diagnosed Myeloma Patients Results in Decreased Incidence and Severity of Chronic GVHD.Transplant Cell Ther2023
37726096Corrigendum to' UM171 expansion of cord blood improves donor availability and HLA matching for all patients, including minorities' [Transplantation and Cellular Therapy 28/7 (2022) 410-410.Transplant Cell Ther2023
37639313GPRC5C drives branched-chain amino acid metabolism in leukemogenesis.Blood Adv2023
37161072Towards clinically meaningful expansion of human HSCs.Cell Res2023
37467030Improved outcomes of UM171-expanded cord blood transplantation compared with other graft sources: real-world evidence.Blood Adv2023
36243319Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge.Transplant Cell Ther2023
34845367Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study.Bone Marrow Transplant2022
35797243HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition.Blood Adv2022
35725769Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells.Nat Cell Biol2022
35589701Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia.Nat Commun2022
35849707Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia.Blood Adv2022
36005208Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome.Curr Oncol2022
34954149Real-World Outcomes of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed/Refractory Hodgkin Lymphoma in the Era of Novel Therapies: A Canadian Perspective.Transplant Cell Ther2022
35286394CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.Blood Adv2022
35253392CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.EMBO Mol Med2022
35311667UM171 Expansion of Cord Blood Improves Donor Availability and HLA Matching For All Patients, Including Minorities.Transplant Cell Ther2022
34731885Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.Blood Adv2022
33022376UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.Transplant Cell Ther2021
33740418Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.Immunity2021
33931647Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.Nat Commun2021
33692124Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.Proc Natl Acad Sci U S A2021
34499717HLF expression defines the human hematopoietic stem cell state.Blood2021
34383740A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene.PLoS Genet2021
34762055Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: Scoping Literature Review.J Med Internet Res2021
34326171Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML.J Immunother Cancer2021
33417871UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.Cell Stem Cell2021
31521818Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma.Biol Blood Marrow Transplant2020
31704264Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.Lancet Haematol2020
32981146Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only.Clin Transplant2020
32749758Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors.Eur J Haematol2020
32315381High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML.Blood2020
31300747Genetic characterization of ABT-199 sensitivity in human AML.Leukemia2020
30654975Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease.Leuk Res2019
31703090UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal.PLoS One2019
31861091Pathways, Processes, and Candidate Drugs Associated with a <i>Hoxa</i> Cluster-Dependency Model of Leukemia.Cancers (Basel)2019
31182782The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia.Leukemia2019
31287994Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.Cancer Cell2019
31427380Targeted variant detection using unaligned RNA-Seq reads.Life Sci Alliance2019
31340144Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells.Cell Rep2019
31392669Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting.Appl Health Econ Health Policy2019
31219578A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.Nucleic Acids Res2019
30820024Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia.Blood Cancer J2019
31135970Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis.Br J Haematol2019
31076446Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML.Blood2019
30782614Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition.Blood Adv2019
29431698MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia.Cancer Discov2018
30101153UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells.Mol Ther Methods Clin Dev2018
30061630High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia.Blood Cancer J2018
29550835Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin.Leukemia2018
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Collaborators

Marie-Jos??e H??bert
Universite de Montreal
Co-authored papers 50
Jalila Chagraoui
Institute for Research in Immunology and Cancer, University of Montreal
Co-authored papers 35
Jana Krosl
The Leucegene Project at Institute for Research in Immunology and Cancer.
Co-authored papers 30
Denis-Claude Roy
Universite de Montreal
Co-authored papers 26
Anne Marinier
Institute for Research in Immunology and Cancer
Co-authored papers 16
Patrick Gendron
University of Montreal
Co-authored papers 12
Unnur Thorsteinsdottir
University of Iceland
Co-authored papers 11
Iman Fares
Dana-Farber Cancer Institute
Co-authored papers 8
Sylvain Meloche
Institute for Research in Immunology and Cancer
Co-authored papers 8
Trang Hoang
Department of Biomedical Science and Center for Bio-Nanomaterials, Daegu University
Co-authored papers 5
Philippe P Roux
IRIC - University of Montreal
Co-authored papers 5
Peter W Zandstra
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Andr?? Haman
Universite de Montreal, Institute for Research in Immunology and Cancer
Co-authored papers 4
Mathieu Tremblay
Universite de Montreal, Institute for Research in Immunology and Cancer
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Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
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Jasmin Coulombe-Huntington
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 3
Diogo F T Veiga
University of Campinas (UNICAMP)
Co-authored papers 3
Takuro Nakamura
Tohoku University Graduate School of Medicine
Co-authored papers 2
Paul S Maddox
University of North Carolina at Chapel Hill
Co-authored papers 2
Louis Gaboury
Institute for Research in Immunology and Cancer (IRIC), University of Montreal
Co-authored papers 2
L??o Aubert
IRIC - University of Montreal
Co-authored papers 2
Ma'n H Zawati
McGill University
Co-authored papers 2
Wolfgang E Berdel
University Hospital Munster
Co-authored papers 2
Bastien Gerby
Universite de Toulouse, Inserm, Universite Toulouse III-Paul Sabatier
Co-authored papers 2
Miguel A Andrade-Navarro
Institute of Organismic and Molecular Evolution, Johannes Gutenberg University
Co-authored papers 1
Milena Kosic
Leslie Dan Faculty of Pharmacy and Department of Biochemistry, University of Toronto
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Maura Gasparetto
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Richard Koche
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Release 1.2