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Author Details

Robert W Sobol
University of South Alabama
1987
141
50
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36702010Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility.DNA Repair (Amst)2023
38068959A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1.Int J Mol Sci2023
37645072Editorial: DNA repair and nucleic acid therapeutics in cancer.NAR Cancer2023
37220749A multi-scale map of protein assemblies in the DNA damage response.Cell Syst2023
37153737Targeting HSF1 for cancer treatment: mechanisms and inhibitor development.Theranostics2023
37313377Co-creation and engagement in a DNA integrity cohort study.J Clin Transl Sci2023
36515828Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage.Methods Mol Biol2023
36598947WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency.Proc Natl Acad Sci U S A2023
35219626Double-strand breaks: When DNA repair events accidentally meet.DNA Repair (Amst)2022
35505094Correction to: Thymine DNA glycosylase as a novel target for melanoma.Oncogene2022
36110898A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage.NAR Genom Bioinform2022
36247007Editorial: Mechanistic studies of genome integrity, environmental health, and cancer etiology.Front Cell Dev Biol2022
35954352Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens.Cancers (Basel)2022
35892832Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD<sup>+</sup> Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase.Cancers (Basel)2022
34198612Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair.Biology (Basel)2021
34934174A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.Commun Biol2021
34731617Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD<sup>+</sup>/SIRT6 axis.Cell Rep2021
34548489SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity.Nat Commun2021
34806016NAD<sup>+</sup> bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells.NAR Cancer2021
34365116CometChip enables parallel analysis of multiple DNA repair activities.DNA Repair (Amst)2021
33046907Regulation of ALT-associated homology-directed repair by polyADP-ribosylation.Nat Struct Mol Biol2020
31959836Extracellular NAD<sup>+</sup> enhances PARP-dependent DNA repair capacity independently of CD73 activity.Sci Rep2020
33087267NAD<sup>+</sup>-mediated regulation of mammalian base excision repair.DNA Repair (Amst)2020
30674989Thymine DNA glycosylase as a novel target for melanoma.Oncogene2019
30082909Immunoregulatory protein B7-H3 regulates cancer stem cell enrichment and drug resistance through MVP-mediated MEK activation.Oncogene2019
31287140Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.Nucleic Acids Res2019
31476572Modification of the base excision repair enzyme MBD4 by the small ubiquitin-like molecule SUMO1.DNA Repair (Amst)2019
30852368Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage.DNA Repair (Amst)2019
29426857Next generation high throughput DNA damage detection platform for genotoxic compound screening.Sci Rep2018
30167090DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity.Oncotarget2018
29536573Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles.Environ Mol Mutagen2018
29799191Camptothecin Efficacy to Poison Top1 Is Altered by Bisphenol A in Mouse Embryonic Fibroblasts.Chem Res Toxicol2018
27994057FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.J Biol Chem2017
28110804Differential role of base excision repair proteins in mediating cisplatin cytotoxicity.DNA Repair (Amst)2017
28458064Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease.Mutat Res2017
28333622Constrained Inversion and Spectral Unmixing in Multispectral Optoacoustic Tomography.IEEE Trans Med Imaging2017
29021553Development of a Cell-Based Assay for Measuring Base Excision Repair Responses.Sci Rep2017
28559431DNA Polymerase Beta Participates in Mitochondrial DNA Repair.Mol Cell Biol2017
27816326Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities.Trends Biochem Sci2017
28003368UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase.J Biol Chem2017
27354815Administration of polysaccharide from Panax notoginseng prolonged the survival of H22 tumor-bearing mice.Onco Targets Ther2016
29156686Crosstalk between mismatch repair and base excision repair in human gastric cancer.Oncotarget2016
27820808Oxidative guanine base damage regulates human telomerase activity.Nat Struct Mol Biol2016
27759097Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD<sup>+</sup> and retinoic acid.Sci Rep2016
27453043A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.Mol Cell2016
27298254The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products.Nucleic Acids Res2016
2558618315-Hydroxyprostaglandin dehydrogenase generation of electrophilic lipid signaling mediators from hydroxy Ï¿-3 fatty acids.J Biol Chem2015
26437225Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition.Oncotarget2015
26251826Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells.Genom Data2015
26519826Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links.DNA Repair (Amst)2015
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Collaborators

Jianfeng Li
Mitchell Cancer Institute, University of South Alabama
Co-authored papers 26
Christopher A Koczor
Mitchell Cancer Institute, University of South Alabama
Co-authored papers 9
Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 6
Uma R Chandran
Co-authored papers 6
Ian F Pollack
University of Pittsburgh School of Medicine
Co-authored papers 5
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 4
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 4
Katalin Karikó
Co-authored papers 4
Thomas J Begley
University at Albany
Co-authored papers 3
Pietro Mancuso
Co-authored papers 3
Soumya Luthra
Co-authored papers 3
Katherine Licon
University of California San Diego
Co-authored papers 3
Leona D Samson
Massachusetts Institute of Technology
Co-authored papers 3
Lionel Larue
Institut Curie, PSL Research University, INSERM U1021
Co-authored papers 2
Leroy Worth
University Children's Hospital Regensburg (KUNO)
Co-authored papers 2
Vignesh Sivaganesh
University of the Sciences
Co-authored papers 2
John Paul Shen
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Kimberly A McAllister
Queen's University
Co-authored papers 2
Daniel J Brat
Co-authored papers 2
Jonathan L Finlay
Nationwide Children's Hospital and The Ohio State University
Co-authored papers 2
Bo Hu
Northwestern University Feinberg School of Medicine
Co-authored papers 2
Daniel T Shaughnessy
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 2
Rohith Srivas
Amgen Inc.
Co-authored papers 2
Haico van Attikum
Leiden University Medical Center
Co-authored papers 2
Jennifer R Grandis
University of California san francisco
Co-authored papers 2
Shigeyuki Yokoyama
Shinshu University School of Medicine
Co-authored papers 2
Jia L Xu
Stem Cell Program and Institute for Genomic Medicine, University of California
Co-authored papers 2
Daniel Pekin
University of California
Co-authored papers 2
Andrew M Gross
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Release 1.2