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Author Details

Steven Finkbeiner
J. David Gladstone Institutes
1988
155
69
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36764301Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects.Neuron2023
36712069Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis.bioRxiv2023
36764301Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects.Neuron2023
36950378The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism.Cell Genom2023
36603024Nuclear accumulation of host transcripts during Zika Virus Infection.PLoS Pathog2023
36950378The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism.Cell Genom2023
36712069Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis.bioRxiv2023
36603024Nuclear accumulation of host transcripts during Zika Virus Infection.PLoS Pathog2023
35266954The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.J Cell Biol2022
36093369Fluorescently labeled nuclear morphology is highly informative of neurotoxicity.Front Toxicol2022
35378365Generation of two human induced pluripotent stem cell lines from fibroblasts of Parkinson's disease patients carrying the ILE368ASN mutation in PINK1 (LCSBi002) and the R275W mutation in Parkin (LCSBI004).Stem Cell Res2022
35865413Huntington's disease iPSC models-using human patient cells to understand the pathology caused by expanded CAG repeats.Fac Rev2022
34981791Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.J Clin Invest2022
35266954The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.J Cell Biol2022
35115730Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.Nat Neurosci2022
35378365Generation of two human induced pluripotent stem cell lines from fibroblasts of Parkinson's disease patients carrying the ILE368ASN mutation in PINK1 (LCSBi002) and the R275W mutation in Parkin (LCSBI004).Stem Cell Res2022
35865413Huntington's disease iPSC models-using human patient cells to understand the pathology caused by expanded CAG repeats.Fac Rev2022
36093369Fluorescently labeled nuclear morphology is highly informative of neurotoxicity.Front Toxicol2022
34981791Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.J Clin Invest2022
35115730Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.Nat Neurosci2022
34362731Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation.Sci Adv2021
33792567ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.J Clin Invest2021
34746930Huntington's disease mouse models: unraveling the pathology caused by CAG repeat expansion.Fac Rev2021
34626895Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched.Stem Cell Res2021
34736041Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006).Stem Cell Res2021
34496257Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.Cell Rep2021
34489414Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.Nat Commun2021
34826737Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007).Stem Cell Res2021
34878844Superhuman cell death detection with biomarker-optimized neural networks.Sci Adv2021
34362731Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation.Sci Adv2021
33792567ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.J Clin Invest2021
34878844Superhuman cell death detection with biomarker-optimized neural networks.Sci Adv2021
34736041Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006).Stem Cell Res2021
34496257Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.Cell Rep2021
34489414Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.Nat Commun2021
34746930Huntington's disease mouse models: unraveling the pathology caused by CAG repeat expansion.Fac Rev2021
34626895Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched.Stem Cell Res2021
34826737Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007).Stem Cell Res2021
30936119The Autophagy Lysosomal Pathway and Neurodegeneration.Cold Spring Harb Perspect Biol2020
32081961Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.Nat Commun2020
31962288Approaches to develop therapeutics to treat frontotemporal dementia.Neuropharmacology2020
32382035Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.Nat Commun2020
32977020Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease.Neurobiol Dis2020
30936119The Autophagy Lysosomal Pathway and Neurodegeneration.Cold Spring Harb Perspect Biol2020
32081961Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.Nat Commun2020
31962288Approaches to develop therapeutics to treat frontotemporal dementia.Neuropharmacology2020
32977020Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease.Neurobiol Dis2020
32382035Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.Nat Commun2020
30696728Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway.J Neurosci2019
31179783Cell death assays for neurodegenerative disease drug discovery.Expert Opin Drug Discov2019
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Collaborators

Center for Systems and Therapeutics, J. David Gladstone Institutes
Co-authored papers 14
University of Michigan ann arbor
Co-authored papers 14
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Co-authored papers 13
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University of California san francisco
Co-authored papers 6
University of California San Francisco
Co-authored papers 5
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Albert Einstein College of Medicine
Co-authored papers 5
National Institute On Aging
Co-authored papers 4
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University of California San Francisco
Co-authored papers 4
Stanford University
Co-authored papers 3
Smidt Heart Institute, Cedars-Sinai Medical Center
Co-authored papers 3
College des medecins du Quebec
Co-authored papers 3
University of Pennsylvania
Co-authored papers 3
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 3
Co-authored papers 3
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 3
Co-authored papers 3
Weizmann Institute of Science
Co-authored papers 3
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Grenoble Institut Neurosciences, INSERM, Universite Grenoble Alpes
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UCSF Weill Institute for Neurosciences, University of California san francisco
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Gladstone Institute of Neurological Disease, Gladstone Institutes
Co-authored papers 3
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 3
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 3