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Author Details

Gian Luca Negri
British Columbia Cancer Research Institute
2013
36
18
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37812652Surface and Global Proteome Analyses Identify ENPP1 and Other Surface Proteins as Actionable Immunotherapeutic Targets in Ewing Sarcoma.Clin Cancer Res2024
36701129PeptideRanger: An R Package to Optimize Synthetic Peptide Selection for Mass Spectrometry Applications.J Proteome Res2023
37691934MyD88-dependent Toll-like receptor 2 signaling modulates macrophage activation on lysate-adsorbed Teflonâ¿¢ AF surfaces in an <i>in vitro</i> biomaterial host response model.Front Immunol2023
37873234ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.bioRxiv2023
37210563Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss.Nat Commun2023
34294889De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer.Cell Death Differ2022
36209277Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.Nat Commun2022
36031730The proteome of clear cell ovarian carcinoma.J Pathol2022
35154156The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation.Front Immunol2022
35173148Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes.Nat Commun2022
34702771Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study.Clin Cancer Res2022
33121982Whole-proteome analysis of mesonephric-derived cancers describes new potential biomarkers.Hum Pathol2021
33603169HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.Oncogene2021
34895312Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression.Epigenetics Chromatin2021
34403484Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation.Nucleic Acids Res2021
34021002Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.Cancer Discov2021
32409304Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type.Clin Cancer Res2020
33355532Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism.Elife2020
32366477HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.Cancer Res2020
30622235HACE1 is a potential tumor suppressor in osteosarcoma.Cell Death Dis2019
31668005Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis.EMBO Rep2019
31236944Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma.J Pathol2019
31506296Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast.J Biol Chem2019
31000598Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.Proc Natl Acad Sci U S A2019
29712925The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.Nat Commun2018
29961428Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.Acta Neuropathol Commun2018
29606589The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.Mol Cell2018
27752775eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.Acta Neuropathol2017
28554894Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.EMBO J2017
28574509MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation.Cell Death Differ2017
27605385Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine.Sci Rep2016
25965573Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis.Cancer Cell2015
26496706The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition.PLoS Genet2015
26041741Eradication of B-ALL using chimeric antigen receptor-expressing T cells targeting the TSLPR oncoprotein.Blood2015
23407553Quantitative genetic-interaction mapping in mammalian cells.Nat Methods2013
24009531High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8.PLoS Genet2013
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Collaborators

Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 16
Alberto Delaidelli
Co-authored papers 9
David G Huntsman
University of British Columbia
Co-authored papers 6
Maria J Aristizabal
Queen's University
Co-authored papers 5
Michael S Kobor
University of British Columbia
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 4
Cyril B Gilks
University of British Columbia
Co-authored papers 3
Gerard Cagney
Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 3
Gabriel Leprivier
Institute of Neuropathology, Heinrich-Heine University Dusseldorf
Co-authored papers 3
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 3
John M Maris
Children's Hospital of Philadelphia
Co-authored papers 3
Eugene T Dillon
Conway Institute of Biomolecular and Biomedical Research
Co-authored papers 2
Sriganesh Jammula
Early Cancer Institute, Hutchison Research Centre, University of Cambridge
Co-authored papers 2
Ariane Watson
University College Dublin
Co-authored papers 2
Ryan D Morin
Simon Fraser University
Co-authored papers 2
Diego Pasini
European Institute of Oncology IRCCS
Co-authored papers 2
Richard A Moore
Co-authored papers 2
Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 2
Kieran Wynne
University College Dublin
Co-authored papers 2
Gundula Streubel
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 2
Darren J Fitzpatrick
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 2
Joris J Benschop
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 2
Marco A Marra
University of British Columbia
Co-authored papers 2
Steven J M Jones
University of British Columbia
Co-authored papers 2
Michael S Anglesio
University of British Columbia
Co-authored papers 2
Andrea Scelfo
Institut Curie, PSL Research University, CNRS
Co-authored papers 2
Didier Surdez
Balgrist University Hospital, University of Zurich (UZH)
Co-authored papers 2
Samuel Leung
University of British Columbia
Co-authored papers 2
Yuzhuo Wang
University of British Columbia
Co-authored papers 2
Adrian P Bracken
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers 2
Release 1.2