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Author Details

Yapeng Su
Fred Hutchinson Cancer Research Center, USA Clinical Research Division
2015
31
17
PMIDPaper TitleJournal TitlePublished Year
37001518Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities.Cell Syst2023
37883974T cell receptor sequences are the dominant factor contributing to the phenotype of CD8<sup>+</sup> T cells with specificities against immunogenic viral antigens.Cell Rep2023
37193826Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.Commun Biol2023
37324018Editorial: Systems biology and single-cell analysis of cancer metabolism and its role in cancer emergent properties.Front Oncol2023
37202473Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions.Commun Chem2023
34489601Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19.Nat Biotechnol2022
36817759Angiotensin-Converting Enzyme (ACE) Inhibitors May Moderate COVID-19 Hyperinflammatory Response: An Observational Study with Deep Immunophenotyping.Health Data Sci2022
36679852Reinfection with SARS-CoV-2 and Waning Humoral Immunity: A Case Report.Vaccines (Basel)2022
36415462Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis.Res Sq2022
35875150Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer.Front Oncol2022
36066491Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression.J Exp Med2022
35258337KIR<sup>+</sup>CD8<sup>+</sup> T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.Science2022
34981055Human KIR <sup>+</sup> CD8 <sup>+</sup> T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19.bioRxiv2021
33765435Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity across viruses.Immunity2021
34919800HLA-A<sup>⿿</sup>02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses.Cell Rep2021
32393797Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line.Nat Commun2020
33171100Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.Cell2020
32973134Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells.Nat Commun2020
32766585Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.bioRxiv2020
32907318Visualizing Subcellular Enrichment of Glycogen in Live Cancer Cells by Stimulated Raman Scattering.Anal Chem2020
30700903T cell antigen discovery via trogocytosis.Nat Methods2019
31484081Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.Cell Rep2019
31166947Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance.PLoS Comput Biol2019
29360859A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication.PLoS One2018
30178802Integrated measurement of intracellular proteins and transcripts in single cells.Lab Chip2018
29555645Epigenetic silencing of miR-125b is required for normal B-cell development.Blood2018
29229836Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.Proc Natl Acad Sci U S A2017
28128880Single cell proteomics in biomedicine: High-dimensional data acquisition, visualization, and analysis.Proteomics2017
27070703Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.Cancer Cell2016
26916347Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells.J Am Chem Soc2016
25789560Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells.J Am Chem Soc2015
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Collaborators

James R Heath
Institute of Systems Biology, University of Washington
Co-authored papers 28
Antoni Ribas
University of California Los Angeles (university of california los angeles)
Co-authored papers 7
Mark M Davis
Co-authored papers 6
Jennifer J Hadlock
Institute for Systems Biology
Co-authored papers 5
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Institute for Systems Biology
Co-authored papers 3
Ansuman T Satpathy
Stanford University
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Leroy Hood
Center for Phenomic Health, The Buck Institute for Research on Aging
Co-authored papers 3
Donghui Cheng
University of California los angeles
Co-authored papers 3
Andrew T Magis
Institute for Systems Biology
Co-authored papers 3
Owen N Witte
University of California los angeles
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Raphael Gottardo
Fred Hutchinson Cancer Center
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Naeha Subramanian
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Alan Aderem
Seattle Children's Research Institute
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Jocelyn T Kim
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Stephen L Hauser
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William H Robinson
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University of California los angeles
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Institute for Systems Biology
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Jesse M Zaretsky
University of California los angeles
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Paul J Utz
Co-authored papers 2
Jorge R Oksenberg
Co-authored papers 2
Lars M Steinmetz
Stanford University
Co-authored papers 2
Garry P Nolan
Stanford University School of Medicine
Co-authored papers 1
Jared C Roach
Institute for Systems Biology
Co-authored papers 1
Nathanael J Bangayan
University of California los angeles
Co-authored papers 1
Webster K Cavenee
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 1
Dave S B Hoon
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Charles D James
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Release 1.2