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Author Details
Full Name
Wyatt T Clark
Affiliation
BioMarin Pharmaceutical Inc.
ORCID
Career Start Year
2008
Papers
18
H Index
11
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37480112
Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix.
Genome Biol
2023
33850126
Identifying therapeutic drug targets using bidirectional effect genes.
Nat Commun
2021
31342580
Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016.
Hum Mutat
2019
31720227
Characterization of glycan substrates accumulating in GM1 Gangliosidosis.
Mol Genet Metab Rep
2019
29979746
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidence.
PLoS One
2018
27604469
An expanded evaluation of protein function prediction methods shows an improvement in accuracy.
Genome Biol
2016
26028266
Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms.
Nat Commun
2015
26346554
Erratum: analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms.
Nat Commun
2015
24297558
Vector quantization kernels for the classification of protein sequences and structures.
Pac Symp Biocomput
2014
25161254
The impact of incomplete knowledge on the evaluation of protein function prediction: a structured-output learning perspective.
Bioinformatics
2014
25157146
Comparative analysis of pseudogenes across three phyla.
Proc Natl Acad Sci U S A
2014
23353650
A large-scale evaluation of computational protein function prediction.
Nat Methods
2013
23813009
Information-theoretic evaluation of predicted ontological annotations.
Bioinformatics
2013
21695233
Testing the ortholog conjecture with comparative functional genomic data from mammals.
PLoS Comput Biol
2011
21796725
Prediction of functional regulatory SNPs in monogenic and complex disease.
Hum Mutat
2011
21671271
Analysis of protein function and its prediction from amino acid sequence.
Proteins
2011
18300252
An integrated approach to inferring gene-disease associations in humans.
Proteins
2008
18508441
From protein-disease associations to disease informatics.
Front Biosci
2008
1 - 18 of 18
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