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Author Details

Wyatt T Clark
BioMarin Pharmaceutical Inc.
2008
18
11
PMIDPaper TitleJournal TitlePublished Year
37480112Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix.Genome Biol2023
33850126Identifying therapeutic drug targets using bidirectional effect genes.Nat Commun2021
31342580Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016.Hum Mutat2019
31720227Characterization of glycan substrates accumulating in GM1 Gangliosidosis.Mol Genet Metab Rep2019
29979746Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidence.PLoS One2018
27604469An expanded evaluation of protein function prediction methods shows an improvement in accuracy.Genome Biol2016
26028266Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms.Nat Commun2015
26346554Erratum: analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms.Nat Commun2015
24297558Vector quantization kernels for the classification of protein sequences and structures.Pac Symp Biocomput2014
25161254The impact of incomplete knowledge on the evaluation of protein function prediction: a structured-output learning perspective.Bioinformatics2014
25157146Comparative analysis of pseudogenes across three phyla.Proc Natl Acad Sci U S A2014
23353650A large-scale evaluation of computational protein function prediction.Nat Methods2013
23813009Information-theoretic evaluation of predicted ontological annotations.Bioinformatics2013
21695233Testing the ortholog conjecture with comparative functional genomic data from mammals.PLoS Comput Biol2011
21796725Prediction of functional regulatory SNPs in monogenic and complex disease.Hum Mutat2011
21671271Analysis of protein function and its prediction from amino acid sequence.Proteins2011
18300252An integrated approach to inferring gene-disease associations in humans.Proteins2008
18508441From protein-disease associations to disease informatics.Front Biosci2008
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Collaborators

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University of Washington
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Yale University
Co-authored papers 3
Iowa State University
Co-authored papers 3
University of California berkeley
Co-authored papers 3
Department of Pharmacy and Biotechnology, University of Bologna
Co-authored papers 3
Wellcome Sanger Institute
Co-authored papers 2
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European Bioinformatics Institute (EMBL-EBI)
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University of California san francisco
Co-authored papers 2
University of Bristol
Co-authored papers 2
Department of Pharmacy and Biotechnology, University of Bologna
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University of Padova
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Inc. San Diego
Co-authored papers 2
Colorado State University
Co-authored papers 2
Institute of Life Sciences, The Hebrew University of Jerusalem
Co-authored papers 2
National Centre for Infections in Cancer, 5Peter MacCallum Cancer Centre
Co-authored papers 2
Purdue University
Co-authored papers 2
University College London
Co-authored papers 2
ETH Zurich, Universitatstrasse 19
Co-authored papers 2
Institute of Biostatistics, Fudan University
Co-authored papers 2
Fudan University
Co-authored papers 2
Baylor College of Medicine
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Technical University of Munich (TUM)
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Yale University
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Imperial College London
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Royal Holloway University of London
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University of Glasgow
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University of Helsinki and Helsinki University Hospital
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University of Colorado School of Medicine
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