Author details

Full Name

Christopher M Evans

Affiliation

ORCID

Career Start Year

1997

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36722775	Vagal Reflexes in Airway Hyperreactivity: Novel Pathways and a Note of Caution for Studies in Mice.		2023
36245281	The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases.	EMBO Journal	2023
37230504	Towards a better mucolytic.		2023
35239513	Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease.	Journal of Clinical Investigation	2022
35881171	Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced by .	American Journal of Physiology - Lung Cellular and Molecular Physiology	2022
35608953	Aberrant Multiciliogenesis in Idiopathic Pulmonary Fibrosis.	American Journal of Respiratory Cell and Molecular Biology	2022
33753897	Characterizing mucociliary clearance in young children with cystic fibrosis.	Pediatr Res	2022
34375594	Mucus.	Current Biology	2021
33651669	Can Eosinophils Prevent Lung Injury? Ask PHIL.	American Journal of Respiratory Cell and Molecular Biology	2021
34453837	Mast Cells Promote Nitrogen Mustard-Mediated Toxicity in the Lung Associated With Proinflammatory Cytokine and Bioactive Lipid Mediator Production.	Toxicological Sciences	2021
32385500	Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis.	Inflammatory Bowel Diseases	2020
31600081	It Takes 1 for Type 2: IL-1 Receptor Mediates Eosinophilia in Scnn1b Transgenic Mice.	American Journal of Respiratory Cell and Molecular Biology	2020
32427408	Changes in mucociliary clearance over time in children with cystic fibrosis.	Pediatric Pulmonology	2020
32348677	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2020
31393853	Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles.	JCI Insight	2019
31582416	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	Journal of Experimental Medicine	2019
31573335	Muc5b Enhances Murine Honeycomb-like Cyst Formation.	American Journal of Respiratory Cell and Molecular Biology	2019
30252497	Dawn of a New Era in the Diagnosis and Treatment of Airway Mucus Dysfunction.	American Journal of Respiratory and Critical Care Medicine	2019
30721150	Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.	JCI Insight	2019
30936493	The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.	Nat Immunol	2019
29802217	Role of mucins in lung homeostasis: regulated expression and biosynthesis in health and disease.	Biochemical Society Transactions	2018
28719757	The Plasma Concentration of MUC5B Is Associated with Clinical Outcomes in Paraquat-poisoned Patients.	American Journal of Respiratory and Critical Care Medicine	2018
30431350	Mucociliary Defense: Emerging Cellular, Molecular, and Animal Models.	Annals of the American Thoracic Society	2018
30250643	COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1Î± mediated tumor angiogenesis and proliferation.	Oncotarget	2018
30089720	Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.	JCI Insight	2018
30185674	Attached stratified mucus separates bacteria from the epithelial cells in COPD lungs.	JCI insight	2018
29987791	Modulation of Lung Epithelial Cell Function Using Conditional and Inducible Transgenic Approaches.	Methods in Molecular Biology	2018
30560893	Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.	Nature Communications	2018
29723043	SPDEFending the Lung through Mucin Expression.	American Journal of Respiratory Cell and Molecular Biology	2018
29161057	E-Cigarettes: Mucus Measurements Make Marks.	American Journal of Respiratory and Critical Care Medicine	2018
29363670	Noxa/HSP27 complex delays degradation of ubiquitylated IkBÎ± in airway epithelial cells to reduce pulmonary inflammation.	Mucosal Immunology	2018
28272906	Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis.	Am J Respir Cell Mol Biol	2017
28555642	TGF-Î² activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.	Nature Communications	2017
28435155	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	Mucosal Immunology	2017
28931657	Neutrophil transfer of <i>miR-223</i> to lung epithelial cells dampens acute lung injury in mice.	Sci Transl Med	2017
28515178	A model-specific role of microRNA-223 as a mediator of kidney injury during experimental sepsis.	Am J Physiol Renal Physiol	2017
27435107	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	Mucosal Immunology	2017
27587549	Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions.	European Respiratory Journal	2016
26871673	MUC5B Promoter Variant rs35705950 Affects MUC5B Expression in the Distal Airways in Idiopathic Pulmonary Fibrosis.	American Journal of Respiratory and Critical Care Medicine	2016
27027967	Mucins and Their Sugars. Critical Mediators of Hyperreactivity and Inflammation.	Annals of the American Thoracic Society	2016
27853654	Tumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironment.	OncoImmunology	2016
27831803	Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization.	Annals of the American Thoracic Society	2016
27630174	Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways.	Physiological Reviews	2016
26503507	Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias.	BMC Genomics	2015
25497369	Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.	Journal of Allergy and Clinical Immunology	2015
25490247	Antiinflammatory and Antimicrobial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model.	Am J Respir Cell Mol Biol	2015
25687754	The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.	Nature Communications	2015
25858779	MUC5B expression and location in surfactant protein C mutations in children.	Pediatric Pulmonology	2015
25943416	Erratum: Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis.	Mucosal Immunology	2015
25850656	Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis.	Mucosal Immunology	2015