Author details

Full Name

Anthony P Orth

Affiliation

Genomics Institute of the Novartis Research Foundation

ORCID

Career Start Year

1995

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37425696	Proteomic associations with forced expiratory volume - a Mendelian randomisation study.	medRxiv	2023
34526658	EndoBind detects endogenous protein-protein interactions in real time.	Commun Biol	2021
29677517	GPR68 Senses Flow and Is Essential for Vascular Physiology.	Cell	2018
30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Science	2018
30297908	Structure-guided combination therapy to potently improve the function of mutant CFTRs.	Nat Med	2018
28068668	The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERÎ±.	Nature	2017
29245949	Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets.	Oncotarget	2017
27649498	High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor.	PLoS One	2016
25616511	Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich's Ataxia.	J Biomol Screen	2015
24725410	SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.	Cell	2014
25495526	Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.	BMC Cancer	2014
24886841	High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.	PLoS One	2014
23300950	FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.	PLoS One	2013
23918920	An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics.	J Biomol Screen	2013
23603119	Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets.	Mol Cell	2013
22423970	Cofactors required for TLR7- and TLR9-dependent innate immune responses.	Cell Host Microbe	2012
21949408	Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.	Proc Natl Acad Sci U S A	2011
20027183	Human host factors required for influenza virus replication.	Nature	2010
20696907	Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen.	Proc Natl Acad Sci U S A	2010
20622870	Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.	Nat Cell Biol	2010
20672983	Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells.	J Insect Sci	2010
20133595	Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.	Proc Natl Acad Sci U S A	2010
20085741	An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.	Cell Stem Cell	2010
18329275	A small molecule inhibitor of alpha4 integrin-dependent cell migration.	Bioorg Med Chem	2009
19727444	Negative regulators of insulin signaling revealed in a genome-wide functional screen.	PLoS One	2009
19805117	A genomic screen identifies TYRO3 as a MITF regulator in melanoma.	Proc Natl Acad Sci U S A	2009
19433259	Juvenile hormone regulation of Drosophila Epac--a guanine nucleotide exchange factor.	Mol Cell Endocrinol	2009
18213395	Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling.	PLoS One	2008
20161828	Cellular Ser/Thr-kinase assays using generic peptide substrates.	Curr Chem Genomics	2008
18854154	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	Cell	2008
18464898	Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.	PLoS Genet	2008
17130249	Microplate orbital mixing improves high-throughput cell-based reporter assay readouts.	J Biomol Screen	2007
18077367	A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway.	Proc Natl Acad Sci U S A	2007
17628283	Effects of stress on the hemolymph juvenile hormone binding protein titers of Manduca sexta.	Insect Biochem Mol Biol	2007
17828270	A probability-based approach for the analysis of large-scale RNAi screens.	Nat Methods	2007
16679294	Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling.	Cell Metab	2006
17001007	Genome-wide functional analysis of human cell-cycle regulators.	Proc Natl Acad Sci U S A	2006
17110210	High-content screening of functional genomic libraries.	Methods Enzymol	2006
16520735	High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol.	Nat Neurosci	2006
16474387	A functional genomics approach to the mode of action of apratoxin A.	Nat Chem Biol	2006
15677333	Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis.	Proc Natl Acad Sci U S A	2005
16141075	A strategy for probing the function of noncoding RNAs finds a repressor of NFAT.	Science	2005
16024821	Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis.	Genome Res	2005
14688408	An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.	Proc Natl Acad Sci U S A	2004
15584864	The promise of genomics to identify novel therapeutic targets.	Expert Opin Ther Targets	2004
12459204	Sequence, structure and expression of the hemolymph juvenile hormone binding protein gene in the tobacco hornworm, Manduca sexta.	Insect Biochem Mol Biol	2003
14514886	Genome-scale functional profiling of the mammalian AP-1 signaling pathway.	Proc Natl Acad Sci U S A	2003
14506290	Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.	Proc Natl Acad Sci U S A	2003
14599499	Embryonic expression of juvenile hormone binding protein and its relationship to the toxic effects of juvenile hormone in Manduca sexta.	Insect Biochem Mol Biol	2003
14580720	Allelic variation in the hemolymph juvenile hormone binding protein gene of Manduca sexta.	Mol Cell Endocrinol	2003

1 - 50 of 54

Rabi Murad

Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 2014

Number of shared co-authors 2

Min Liu

Xiamen University

Career Start Year 2004

Number of shared co-authors 0

Bingbing Yuan

Whitehead Institute for Biomedical Research

Career Start Year 2000

Number of shared co-authors 1

Peter White

The Ohio State University

Career Start Year 2000

Number of shared co-authors 0

David K Crossman

University of Alabama at Birmingham

Career Start Year 2000

Number of shared co-authors 0

Braden Boone

HudsonAlpha Institute for Biotechnology

Career Start Year 1999

Number of shared co-authors 0

Stacey L Edwards

QIMR Berghofer Medical Research Institute

Career Start Year 1999

Number of shared co-authors 0

Dalia Barsyte-Lovejoy

University of Toronto, College St

Career Start Year 1999

Number of shared co-authors 0

Stephane Angers

Department of Pharmaceutical Sciences, University of Toronto

Career Start Year 1999

Number of shared co-authors 0

Dongquan Chen

University of Alabama at Birmingham

Career Start Year 1997

Number of shared co-authors 0

Reka Toth

German Cancer Research Center (DKFZ)

Career Start Year 1997

Number of shared co-authors 0

Jason Moffat

University of Toronto

Career Start Year 1997

Number of shared co-authors 0

Damarys Loew

Institut Curie, PSL Research University

Career Start Year 1996

Number of shared co-authors 0

Kaylene J Simpson

The University of Melbourne, Peter MacCallum Cancer Centre

Career Start Year 1996

Number of shared co-authors 0

Michael Boutros

German Cancer Research Center (DKFZ) and Heidelberg University

Career Start Year 1995

Number of shared co-authors 2

Gary Hardiman

Institute for Global Food Security, Queen's University Belfast

Career Start Year 1994

Number of shared co-authors 1

Michael A White

University of Georgia

Career Start Year 1994

Number of shared co-authors 2

Ping Wei

Fudan University Shanghai Cancer Center

Career Start Year 1993

Number of shared co-authors 0

David E Root

Broad Institute of Harvard and MIT

Career Start Year 1993

Number of shared co-authors 2

Manfred Koegl

Boehringer Ingelheim RCV GmbH & Co. KG

Career Start Year 1993

Number of shared co-authors 2

Jeffrey J Delrow

Clinical Research Division, Fred Hutchinson Cancer Research Center

Career Start Year 1992

Number of shared co-authors 1

Kevin G Becker

National Institute on Aging, National Institutes of Health

Career Start Year 1992

Number of shared co-authors 0

Glenn S Cowley

Broad Institute of Harvard and MIT

Career Start Year 1990

Number of shared co-authors 0

Timothy C Burn

Incyte Research Institute

Career Start Year 1987

Number of shared co-authors 0

Harukazu Suzuki

RIKEN Center for Integrative Medical Sciences

Career Start Year 1985

Number of shared co-authors 1

Hediye Erdjument-Bromage

Neuroscience Institute, NYU Grossman School of Medicine

Career Start Year 1984

Number of shared co-authors 0

Ralf Kittler

McDermott Center for Human Growth and Development.

Career Start Year 1984

Number of shared co-authors 0

Marian J A Groot Koerkamp

Princess Maxima Center for Pediatric Oncology Research

Career Start Year 1983

Number of shared co-authors 0

Michael Snyder

Stanford University

Career Start Year 1981

Number of shared co-authors 2

Bruce J Aronow

Cincinnati Children's Hospital Medical Center

Career Start Year 1975

Number of shared co-authors 1

row(s) 1 - 30 of 30

Loren Miraglia

Genomics Institute of the Novartis Research Foundation

Co-authored papers 19

Sumit K Chanda

The Scripps Research Institute

Co-authored papers 15

Serge Batalov

Co-authored papers 10

Paul D De Jesus

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 8

Buu Tu

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Co-authored papers 8

Ghislain M C Bonamy

Prestige BioPharma Ltd

Co-authored papers 5

Chih-Yuan Chiang

United States Army Medical Research Institute of Infectious Diseases

Co-authored papers 4

Yingyao Zhou

Genomics Institute of the Novartis Research Foundation

Co-authored papers 4

Ardem Patapoutian

Howard Hughes Medical Institute

Co-authored papers 4

Renate K??nig

Paul-Ehrlich-Institut

Co-authored papers 3

Jeremy S Caldwell

Sirna Therapeutics a former subsidiary of Merck & Co., Inc.

Co-authored papers 3

Andrew I Su

The Scripps Research Institute

Co-authored papers 3

Chunlei Wu

The Scripps Research Institute

Co-authored papers 2

Vilmundur Gudnason

Co-authored papers 2

Trey Ideker (CM4AI)

University of California San Diego

Co-authored papers 2

Scott A Lesley

Merck & Co., Inc.

Co-authored papers 2

Peter K Vogt

Co-authored papers 2

John A T Young

Roche Pharma

Co-authored papers 2

Gung-Wei Chirn

Co-authored papers 2

Amanda M Opaluch

Sanford-Burnham Medical Research Institute

Co-authored papers 2

Jennifer L Harris

Co-authored papers 2

Valur Emilsson

Co-authored papers 2

Thor Aspelund

Co-authored papers 2

Inder M Verma

Co-authored papers 2

Sourav Bandyopadhyay

University of California San Francisco

Co-authored papers 2

Atsushi Inoue

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 1

Victor Nizet

university of california san diego School of Medicine

Co-authored papers 1

Bin Zhang

Graduate School of Medicine, The University of Tokyo

Co-authored papers 1

Lenore J Launer

Co-authored papers 1

Costas A Lyssiotis

Co-authored papers 1

1 - 30

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