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Author Details

Christine M Hulette
Duke University
1985
155
63
PMIDPaper TitleJournal TitlePublished Year
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
31688885Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.JAMA2019
31306170Creutzfeldt-Jakob Disease Mimicking Neurosyphilis: A Complex Presentation, Histopathological Findings, and Special Precautions for Autopsy.Am J Forensic Med Pathol2019
30295806Fatal Granulomatous Amebic Encephalitis in a Heart Transplant Patient: Clinical, Radiographic, and Autopsy Findings.J Neuropathol Exp Neurol2018
29930110Analysis of shared heritability in common disorders of the brain.Science2018
30137212The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.Brain2018
28864461Somatic uniparental disomy of Chromosome 16p in hemimegalencephaly.Cold Spring Harb Mol Case Stud2017
31239998Cerebral Toxoplasmosis: A Case Report with Correlation of Radiographic Imaging, Surgical Pathology, and Autopsy Findings.Acad Forensic Pathol2017
28714976Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Nat Genet2017
26799155Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosis.Epilepsia2016
25531812Rarity of the Alzheimer disease-protective APP A673T variant in the United States.JAMA Neurol2015
26043869Postmortem diffusion MRI of the human brainstem and thalamus for deep brain stimulator electrode localization.Hum Brain Mapp2015
24442578TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.Acta Neuropathol2014
25199842Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.JAMA Neurol2014
25144333Atypical lymphocytic angiitis of the optic nerve and central nervous system.JAMA Ophthalmol2014
21185108The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression.Neurobiol Aging2012
22722634Novel late-onset Alzheimer disease loci variants associate with brain gene expression.Neurology2012
22487856Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.J Neuropathol Exp Neurol2012
21172323Intracranial volume and dementia: some evidence in support of the cerebral reserve hypothesis.Brain Res2011
21888480Sudden death from diffuse leptomeningeal oligodendrogliomatosis.J Neurosurg Spine2011
21460841Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.Nat Genet2011
21046180The effect of SNCA 3' region on the levels of SNCA-112 splicing variant.Neurogenetics2011
21075060Metabolomic changes in autopsy-confirmed Alzheimer's disease.Alzheimers Dement2011
18572275Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology.Neurobiol Aging2010
20488256Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.Biochim Biophys Acta2010
20154673Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.Nat Genet2010
20061627Genome-wide scan of copy number variation in late-onset Alzheimer's disease.J Alzheimers Dis2010
17723255Clinical and pathological features of an Alzheimer's disease patient with the MAPT Delta K280 mutation.Neurobiol Aging2009
19834617Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.PLoS One2009
19376612Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease.Neurobiol Aging2009
19372291Twin pairs discordant for neuropathologically confirmed Lewy body dementia.J Neurol Neurosurg Psychiatry2009
19287310Cerebrovascular smooth muscle actin is increased in nondemented subjects with frequent senile plaques at autopsy: implications for the pathogenesis of Alzheimer disease.J Neuropathol Exp Neurol2009
19287308Adult cases of leukoencephalopathy, cerebral calcifications, and cysts: expanding the spectrum of the disorder.J Neuropathol Exp Neurol2009
18361431Longitudinal follow-up of late-onset Alzheimer disease families.Am J Med Genet B Neuropsychiatr Genet2008
19222302Tissue-specific genetic control of splicing: implications for the study of complex traits.PLoS Biol2008
18571782A novel human disease with abnormal prion protein sensitive to protease.Ann Neurol2008
18477662Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage.J Clin Endocrinol Metab2008
18258839Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype.Stroke2008
18270320Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.Physiol Genomics2008
18332434Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.Proc Natl Acad Sci U S A2008
16782234Microvascular injury and blood-brain barrier leakage in Alzheimer's disease.Neurobiol Aging2007
18090918Postmortem delay has minimal effect on brain RNA integrity.J Neuropathol Exp Neurol2007
18090919A novel cerebral microangiopathy with endothelial cell atypia and multifocal white matter lesions: a direct mycoplasmal infection?J Neuropathol Exp Neurol2007
17564920Autopsy-confirmed Alzheimer's disease versus clinically diagnosed Alzheimer's disease in the Cache County Study on Memory and Aging: a comparison of quantitative MRI and neuropsychological findings.J Clin Exp Neuropsychol2007
17706618RB1CC1 insufficiency causes neuronal atrophy through mTOR signaling alteration and involved in the pathology of Alzheimer's diseases.Brain Res2007
17822919A SAGE study of apolipoprotein E3/3, E3/4 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease.Mol Cell Neurosci2007
17343748Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease.Genome Biol2007
17283328Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers.Neurology2007
17077275Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.Physiol Genomics2007
17089130The distribution of cerebrovascular amyloid in Alzheimer's disease varies with ApoE genotype.Acta Neuropathol2007
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Co-authored papers 23
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University of Pennsylvania
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Cleveland Institute for Computational Biology, Case Western Reserve University
Co-authored papers 12
Stanford University
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Mayo Clinic Jacksonville
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National Institute On Aging
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Oregon Center for Aging & Technology
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Massachusetts General Hospital and Harvard Medical School
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Washington University School of Medicine
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Emory University School of Medicine
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The Center for Applied Genomics, Children's Hospital of Philadelphia
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Cambridge Institute for Medical Research, University of Cambridge
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UCSF Weill Institute for Neurosciences, University of California san francisco
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Massachusetts General Hospital
Co-authored papers 8
University of California Davis
Co-authored papers 8
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Rush University Medical Center
Co-authored papers 8
University of Washington
Co-authored papers 7
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Boston University Chobanian & Avedisian School of Medicine
Co-authored papers 7
Mayo Clinic Florida
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Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 7
Stark Neurosciences Research Institute, Indiana University School of Medicine (IUSM)
Co-authored papers 7
Indiana University School of Medicine
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