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Author Details

Sumedha Gunewardena
University of Kansas Medical Center
2006
89
31
PMIDPaper TitleJournal TitlePublished Year
37745500Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease.bioRxiv2024
36218231Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma.Mol Carcinog2023
37685885LH/hCG Regulation of Circular RNA in Mural Granulosa Cells during the Periovulatory Period in Mice.Int J Mol Sci2023
36979320Exploring Whether Iron Sequestration within the CNS of Patients with Alzheimer's Disease Causes a Functional Iron Deficiency That Advances Neurodegeneration.Brain Sci2023
37208854Identification of follicle-stimulating hormone-responsive genes in Sertoli cells during early postnatal mouse testis development.Andrology2023
37405912Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells.Cell Rep2023
37334609Landscape of Double-Stranded DNA Breaks in Postmortem Brains from Alzheimer's Disease and Non-Demented Individuals.J Alzheimers Dis2023
36877036Sera of Individuals Chronically Infected with Hepatitis B Virus (HBV) Contain Diverse RNA Types Produced by HBV Replication or Derived from Integrated HBV DNA.J Virol2023
36778348Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice.bioRxiv2023
35084807Male-Specific Activation of Lysine Demethylases 5B and 5C Mediates Alcohol-Induced Liver Injury and Hepatocyte Dedifferentiation.Hepatol Commun2022
35772768Heat-induced increases in body temperature in lactating dairy cows: impact on the cumulus and granulosa cell transcriptome of the periovulatory follicle.J Anim Sci2022
35468265Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C.Hepatol Commun2022
35850385GenX induces fibroinflammatory gene expression in primary human hepatocytes.Toxicology2022
36037374Hippo signaling cofactor, WWTR1, at the crossroads of human trophoblast progenitor self-renewal and differentiation.Proc Natl Acad Sci U S A2022
36171419TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis.Nat Commun2022
35984304The START domain mediates Arabidopsis GLABRA2 dimerization and turnover independently of homeodomain DNA binding.Plant Physiol2022
36282915Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis.Proc Natl Acad Sci U S A2022
35093590Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice.Cell Mol Gastroenterol Hepatol2022
35006629Progressive loss of hepatocyte nuclear factor 4 alpha activity in chronic liver diseases in humans.Hepatology2022
35177031Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression.BMC Cancer2022
34022283Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression.Cancer Lett2021
33741948Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro.Nat Commun2021
33562221Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families.Int J Mol Sci2021
33665264Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.Data Brief2021
33745223CCN5 activation by free or encapsulated EGCG is required to render triple-negative breast cancer cell viability and tumor progression.Pharmacol Res Perspect2021
33577554Anti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity.PLoS One2021
33495575Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett's like metaplasia.Lab Invest2021
34766154Histone lysine demethylase 4B regulates general and unique gene expression signatures in hypoxic cancer cells.MedComm (2020)2021
34523155A Western diet with alcohol in drinking water recapitulates features of alcohol-associated liver disease in mice.Alcohol Clin Exp Res2021
34546377Hepatocyte-Specific Deletion of Yes-Associated Protein Improves Recovery From Acetaminophen-Induced Acute Liver Injury.Toxicol Sci2021
32425114RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways.Cell Transplant2020
32045647Comparison of liver regeneration after partial hepatectomy and acetaminophen-induced acute liver failure: A global picture based on transcriptome analysis.Food Chem Toxicol2020
32631996A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver.Proc Natl Acad Sci U S A2020
32681035An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis.Nat Commun2020
32669432TEAD4 ensures postimplantation development by promoting trophoblast self-renewal: An implication in early human pregnancy loss.Proc Natl Acad Sci U S A2020
32513715Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal-fetal exchange interface.Proc Natl Acad Sci U S A2020
30674533Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response.Cancer Res2019
31442435The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice.Gastroenterology2019
31324852Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells.Sci Rep2019
31346607Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggsâ¿ .Biol Reprod2019
30787177CYR61/CCN1 Regulates dCK and CTGF and Causes Gemcitabine-resistant Phenotype in Pancreatic Ductal Adenocarcinoma.Mol Cancer Ther2019
30899425Super-enhancers: novel target for pancreatic ductal adenocarcinoma.Oncotarget2019
30520062Hepatocyte Nuclear Factor 4 Alpha Activation Is Essential for Termination of Liver Regeneration in Mice.Hepatology2019
29351058Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis.Radiat Res2018
29987422Micro-RNAs involved in cellular proliferation have altered expression profiles in granulosa of young women with diminished ovarian reserve.J Assist Reprod Genet2018
29781875Feasibility of microRNA profiling in human inner ear perilymph.Neuroreport2018
29672222Macrophage-derived extracellular vesicles mediate smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV infection and substance abuse.FASEB J2018
29634432Differential Gene Expression and Pathway Analysis in Juvenile Nasopharyngeal Angiofibroma Using RNA Sequencing.Otolaryngol Head Neck Surg2018
29491161Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers.J Virol2018
29654721Pleiotropic Role of p53 in Injury and Liver Regeneration after Acetaminophen Overdose.Am J Pathol2018
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Collaborators

Lane K Christenson
University of Kansas Medical Center
Co-authored papers 9
Ossama Tawfik
University of Kansas
Co-authored papers 8
Scott J Weir
University of Kansas Medical Center
Co-authored papers 5
Xiaoman Hong
University of Kansas Medical Center
Co-authored papers 4
Zhaolei Zhang
University of Toronto
Co-authored papers 3
Sushanta K Banerjee
Co-authored papers 2
Adam J Krieg
Oregon Health and Sciences University
Co-authored papers 2
Snigdha Banerjee
Co-authored papers 2
Arnab Ghosh
Co-authored papers 2
Sharad C Mathur
Kansas City VA Medical Center
Co-authored papers 2
Inamul Haque
Co-authored papers 2
Ajay Bansal
Regeneron Pharmaceuticals Inc.
Co-authored papers 2
Vijayalaxmi Gupta
Co-authored papers 1
In-Hee Lee
Co-authored papers 1
Sue A Ingles
Co-authored papers 1
Amit Rastogi
Institute of Liver Transplantation
Co-authored papers 1
Christopher P Austin
St. George's University Medical School
Co-authored papers 1
Kausilia K Krishnadath
Antwerp University Hospital
Co-authored papers 1
Suman Kambhampati
Co-authored papers 1
Gargi Maity
Co-authored papers 1
John A Hanover
Co-authored papers 1
Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
In-Hee Lee
Children's Hospital Boston
Co-authored papers 1
Klaus H Kaestner
Department of Genetics and Institute for Diabetes, University of Pennsylvania
Co-authored papers 1
Jay Sharma
University of California
Co-authored papers 1
Sandipto Sarkar
Co-authored papers 1
Ari Melnick
Co-authored papers 1
Michael J Birrer
Co-authored papers 1
Mukut Sharma
Midwest Veterans' Biomedical Research Foundation, KCVA Medical Center
Co-authored papers 1
Daniel D Von Hoff
Co-authored papers 1
Release 1.2