Author details

Full Name

Joseph D Szustakowski

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34994587	Pursuing Better Biomarkers for Immunotherapy Response in Cancer Through a Crowdsourced Data Challenge.	JCO Precis Oncol	2021
34115965	Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.	Am J Hum Genet	2021
33103912	Modeling performance of sample collection sites using whole exome sequencing metrics.	BioTechniques	2020
32312757	<i>STK11</i> and <i>KEAP1</i> mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort.	ESMO Open	2020
31250328	Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer.	Mol Diagn Ther	2019
30753829	Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer.	Cancer Cell	2019
30785829	First-Line Nivolumab Plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer (CheckMate 568): Outcomes by Programmed Death Ligand 1 and Tumor Mutational Burden as Biomarkers.	Journal of Clinical Oncology	2019
29773717	<i>STK11/LKB1</i> Mutations and PD-1 Inhibitor Resistance in <i>KRAS</i>-Mutant Lung Adenocarcinoma.	Cancer Discov	2018
29658845	Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden.	New England Journal of Medicine	2018
29731394	Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer.	Cancer Cell	2018
28749946	Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors.	PLoS ONE	2017
28457472	Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families.	Am J Hum Genet	2017
26487268	Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.	Nat Commun	2015
25047945	Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis.	Arthritis Rheumatol	2014
25285214	The use of haplotype-specific transcripts improves sample annotation consistency.	Biomark Res	2014
23428642	DeconRNASeq: a statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data.		2013
23687361	LMX1B mutations cause hereditary FSGS without extrarenal involvement.	J Am Soc Nephrol	2013
23348786	RAMP: a bioinformatics framework for researching imaging agents through molecular pathways.	Molecular Imaging	2013
22110609	Optimal deconvolution of transcriptional profiling data using quadratic programming with application to complex clinical blood samples.	PLoS One	2011
21925108	Human cytomegalovirus escapes a naturally occurring neutralizing antibody by incorporating it into assembling virions.		2011
19763933	Bioinformatics analysis of microarray data.	Methods Mol Biol	2009
19398767	Transcriptome changes in renal allograft protocol biopsies at 3 months precede the onset of interstitial fibrosis/tubular atrophy (IF/TA) at 6 months.	Nephrol Dial Transplant	2009
19381295	Identification of novel genes and pathways regulating SREBP transcriptional activity.	PLoS ONE	2009
18822150	Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles.	BioData Mining	2008
17182725	Pyruvate induces mitochondrial biogenesis by a PGC-1 alpha-independent mechanism.	American Journal of Physiology - Cell Physiology	2007
17418099	Estrogen-related receptor alpha is essential for the expression of antioxidant protection genes and mitochondrial function.	Biochemical and Biophysical Research Communications	2007
17370256	From proteomics to systems biology of bacterial pathogens: approaches, tools, and applications.	Proteomics	2007
17550601	Dynamic resolution of functionally related gene sets in response to acute heat stress.	BMC Molecular Biology	2007
17392327	Extending the pathway analysis framework with a test for transcriptional variance implicates novel pathway modulation during myogenic differentiation.		2007
16300922	Identification of novel pathway regulation during myogenic differentiation.	Genomics	2006
16202129	Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural networks.	BMC Bioinformatics	2005
16204127	Less is more: towards an optimal universal description of protein folds.	Bioinformatics	2005
12176930	Computational identification of operons in microbial genomes.	Genome Res	2002
12083723	Gene discovery in the auditory system: characterization of additional cochlear-expressed sequences.	J Assoc Res Otolaryngol	2002
11237011	Initial sequencing and analysis of the human genome.	Nature	2001
10707029	Protein structure alignment using a genetic algorithm.	Proteins	2000