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Author Details

Taha Azad
Ottawa Hospital Research Institute
2014
37
15
PMIDPaper TitleJournal TitlePublished Year
36713447CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.Front Immunol2023
37822719A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.Mol Ther Methods Clin Dev2023
37242495Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.Pharmaceuticals (Basel)2023
37372372Peptides of a Feather: How Computation Is Taking Peptide Therapeutics under Its Wing.Genes (Basel)2023
37236967Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.Nat Commun2023
37100284Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.J Biol Chem2023
36969187Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy <i>via</i> lipid modulation of the tumor microenvironment.Front Immunol2023
34328726Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein.J Med Chem2022
35393414Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.Nat Commun2022
35526097Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.Mol Ther2022
36405739Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.Front Immunol2022
36004308A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S.NAR Genom Bioinform2022
34687845Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.Mol Ther2022
34596787Industrial applications of immobilized nano-biocatalysts.Bioprocess Biosyst Eng2022
34152313Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection.J Vis Exp2021
37579261Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic.ACS Nanosci Au2021
33706157SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.Biosens Bioelectron2021
33668756Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.Int J Mol Sci2021
33809836A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion.Nanomaterials (Basel)2021
33578036Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.Mol Ther2021
34459810Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter.J Vis Exp2021
34658235Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern.ACS Infect Dis2021
31477837A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis.Oncogene2020
33203680Rox8 promotes microRNA-dependent <i>yki</i> messenger RNA decay.Proc Natl Acad Sci U S A2020
32872641Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.Membranes (Basel)2020
32722184Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis.Cancers (Basel)2020
31052445The Role of YAP and TAZ in Angiogenesis and Vascular Mimicry.Cells2019
31635084Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive <i>YAP/TAZ-TEAD</i> Biosensors.Cancers (Basel)2019
31431076A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.FASEB J2019
29339539The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1.Cancer Res2018
30138697TAZ enhances mammary cell proliferation in 3D culture through transcriptional regulation of IRS1.Cell Signal2018
30272653Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor.J Vis Exp2018
29545474PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways.Mol Cancer Res2018
29535383A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.Nat Commun2018
25665080Luciferin-Regenerating Enzyme Mediates Firefly Luciferase Activation Through Direct Effects of D-Cysteine on Luciferase Structure and Activity.Photochem Photobiol2015
25895636Oscillation of apoptosome formation through assembly of truncated Apaf-1.Eur J Pharmacol2015
25002334Split-luciferase complementary assay: applications, recent developments, and future perspectives.Anal Bioanal Chem2014
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Collaborators

Carolina S Ilkow
Ottawa Hospital Research Institute
Co-authored papers 19
John C Bell
Ottawa Hospital Research Institute
Co-authored papers 18
Ragunath Singaravelu
Ottawa Hospital Research Institute
Co-authored papers 15
Mathieu J F Crupi
Cancer Research Institute, Queen's University
Co-authored papers 15
Jean-Simon Diallo
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers 12
Zaid Taha
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers 12
Joanna Poutou
Ottawa Hospital Research Institute
Co-authored papers 11
Julia Petryk
Ottawa Hospital Research Institute
Co-authored papers 10
Abera Surendran
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers 8
Xiao-Peng He
Ottawa Hospital Research Institute
Co-authored papers 8
Adrian Pelin
University of Ottawa
Co-authored papers 7
Sarwat T Khan
Ottawa Hospital Research Institute
Co-authored papers 3
Christiano Tanese de Souza
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers 3
Rebecca C Auer
The Ottawa Hospital Research Institute
Co-authored papers 3
Ashkan Golshani
Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 3
Bahram Samanfar
Agriculture and Agri-Food Canada
Co-authored papers 2
Frank Dehne
Carleton University
Co-authored papers 2
Larissa A Pikor
Ottawa Hospital Research Institute
Co-authored papers 2
Meixiao Zhan
Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University)
Co-authored papers 1
Bradley Austin
Ottawa Hospital Research Institute
Co-authored papers 1
Kun-Liang Guan
University of California San Diego
Co-authored papers 1
Brian A Keller
The Ottawa Hospital/University of Ottawa
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
Alan Melcher
The Institute of Cancer Research
Co-authored papers 1
Victoria A Jennings
Leeds Institute of Medical Research at St James's, University of Leeds
Co-authored papers 1
Hayley E McKay
Ottawa Hospital Research Institute
Co-authored papers 1
Katey J Rayner
University of Ottawa
Co-authored papers 1
Mohsen Hooshyar
Department of Biology and Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 1
Emily E F Brown
Ottawa Hospital Research Institute
Co-authored papers 1
Egon J Jacobus
Ottawa Hospital Research Institute
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