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Author Details

Deborah S Cunninghame Graham
2003
53
32
PMIDPaper TitleJournal TitlePublished Year
37496418A review of genetic risk in systemic lupus erythematosus.2023
36327221COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection.PLoS Genet2022
33308445Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study.Am J Hum Genet2021
33676896Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation.Journal of Biological Chemistry2021
33182226Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at and in Systemic Lupus Erythematosus.International Journal of Molecular Sciences2020
32077931Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity.Human Molecular Genetics2020
31092820Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus.Nature Communications2019
29195081Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].Clin Immunol2018
29912393A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.Hum Mol Genet2018
29207444Abnormal B Cell Development in Systemic Lupus Erythematosus: What the Genetics Tell Us.Arthritis and Rheumatology2018
28062664Mapping eQTLs with RNA-seq reveals novel susceptibility genes, non-coding RNAs and alternative-splicing events in systemic lupus erythematosus.Hum Mol Genet2017
28692793Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.Arthritis Rheumatol2017
28818832B cell OX40L supports T follicular helper cell development and contributes to SLE pathogenesis.Annals of the Rheumatic Diseases2017
28640813Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.PLoS Genet2017
28714469Transancestral mapping and genetic load in systemic lupus erythematosus.Nat Commun2017
29059182Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease.PLoS Genetics2017
26713507X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.Arthritis Rheumatol2016
27109640Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.Clin Immunol2016
27399966Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.Nature Genetics2016
25205108The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.Hum Mol Genet2015
25500883Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.J Clin Invest2015
25865496Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.Am J Hum Genet2015
25604533Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.Arthritis Rheumatol2015
26502338Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.Nat Genet2015
24925725Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.J Am Soc Nephrol2014
24097067Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.Nat Genet2013
23042117CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation.Nat Genet2012
22640752The genetics of lupus: a functional perspective.2012
22046141Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.PLoS Genet2011
21437871Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.Arthritis Rheum2011
21149337Dense mapping of IL18 shows no association in SLE.Hum Mol Genet2011
20528885Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus.Clinical and Experimental Immunology2010
19997561Identification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE).PLoS One2009
19404301Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.Genes Immun2009
19083191Association of the co-stimulator OX40L with systemic lupus erythematosus.Journal of Molecular Medicine2009
19387462The heritability and genetics of complement C3 expression in UK SLE families.Genes and Immunity2009
19664177Genome-wide association studies in systemic lupus erythematosus: a perspective.2009
18216865Association of LY9 in UK and Canadian SLE families.Genes Immun2008
19165918Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.Nat Genet2008
18059267Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.Nat Genet2008
18178846Polymorphisms in the CD3Z gene influence TCRzeta expression in systemic lupus erythematosus patients and healthy controls.Journal of Immunology2008
17384181Association of polymorphisms across the tyrosine kinase gene, TYK2 in UK SLE families.Rheumatology2007
17220214The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus.J Med Genet2007
17412832Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.Proc Natl Acad Sci U S A2007
17189288Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation.Human Molecular Genetics2007
17529978FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity.Nature Genetics2007
17000707Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study.Human Molecular Genetics2006
16052563Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: increased T allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease.Arthritis Rheum2005
15902275No association between E- and L-selectin genes and SLE: soluble L-selectin levels do correlate with genotype and a subset in SLE.Genes and Immunity2005
15196236The candidate gene approach: have murine models informed the study of human SLE?Clinical and Experimental Immunology2004
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