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Author Details

Eric McDade
Washington University St. Louis
1998
138
44
PMIDPaper TitleJournal TitlePublished Year
37740921Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.Alzheimers Dement2024
37634955"And Does That Necessarily Mean Absolutely Alzheimer's?" An Analysis of Questions Raised Following Amyloid PET Results Disclosure.Am J Geriatr Psychiatry2024
36251323Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains.Alzheimers Dement2023
37867465T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease.Hum Brain Mapp2023
37961586Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease.bioRxiv2023
37843849Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.JAMA Neurol2023
37942088Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease.Brain Commun2023
35609137Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease.Alzheimers Dement2023
35362200Biomarker clustering in autosomal dominant Alzheimer's disease.Alzheimers Dement2023
37291760Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease.Aging Cell2023
37085492Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.Nat Commun2023
37016671Axonal damage and astrocytosis are biological correlates of grey matter network integrity loss: a cohort study in autosomal dominant Alzheimer disease.medRxiv2023
37231491Tau accumulation in autosomal dominant Alzheimer's disease: a longitudinal [<sup>18</sup>F]flortaucipir study.Alzheimers Res Ther2023
37202169Longitudinal Relationships of White Matter Hyperintensities and Alzheimer Disease Biomarkers Across the Adult Life Span.Neurology2023
37429916Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN).Nat Neurosci2023
36625756Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease.Brain2023
36522155First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study.J Neurol Neurosurg Psychiatry2023
36919987Lecanamab Ushers in a New Era of Anti-Amyloid Therapy for Alzheimer's Disease.Ann Neurol2023
36843330Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.Ann Neurol2023
36576155Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition.Alzheimers Dement2023
36640138Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease.Alzheimers Dement2023
36798226MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state.medRxiv2023
35241502Resilience at High Resolution: Proteomics in the Study of Brain Reserve.Neurology2022
35678397Alzheimer Disease.Continuum (Minneap Minn)2022
35580594Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.Brain2022
35783127Avoid or Embrace? Practice Effects in Alzheimer's Disease Prevention Trials.Front Aging Neurosci2022
35358703CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease.Neurobiol Dis2022
36544184Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study.Alzheimers Res Ther2022
36238934Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease.Front Aging Neurosci2022
35925685Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan.Brain2022
36348972Evaluation of dose-dependent treatment effects after mid-trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.Alzheimers Dement (Amst)2022
36189728Herpes simplex virus and rates of cognitive decline or whole brain atrophy in the Dominantly Inherited Alzheimer Network.Ann Clin Transl Neurol2022
36151869Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease.Ann Neurol2022
35099506Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease.JAMA Neurol2022
34854530Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease.Alzheimers Dement2022
35246267Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease.Acta Neuropathol Commun2022
35065037Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.Lancet Neurol2022
35212149Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease.Alzheimers Dement2022
30899092The BDNF<sub>Val66Met</sub> SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.Mol Psychiatry2021
33495373Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease.Neurology2021
33725114Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease.Brain2021
34494019Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease.bioRxiv2021
34548654The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.Nat Rev Neurol2021
34155411A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.Nat Med2021
34319442Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease.Acta Neuropathol2021
34289882The informed road map to prevention of Alzheimer Disease: A call to arms.Mol Neurodegener2021
33226734Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes.Alzheimers Dement2021
33430685Resting-State Functional Connectivity Disruption as a Pathological Biomarker in Autosomal Dominant Alzheimer Disease.Brain Connect2021
33480178Modeling autosomal dominant Alzheimer's disease with machine learning.Alzheimers Dement2021
32522711Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease.Neurobiol Dis2020
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Massachusetts General Hospital
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