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Author Details

Mary-Ellen Harper
and Ottawa Institute of Systems Biology, University of Ottawa
1990
201
58
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36691076Parkin coregulates glutathione metabolism in adult mammalian brain.Acta Neuropathol Commun2023
37553427The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis.Cell Mol Immunol2023
37584609Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity.Am J Physiol Endocrinol Metab2023
37315156Deconstructing interindividual variability in energy metabolism: implications for metabolic health.Am J Physiol Endocrinol Metab2023
3714986616p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice.Cell Rep2023
37380764GDF15 promotes weight loss by enhancing energy expenditure in muscle.Nature2023
37077559Novel Homozygous Variant in <i>COQ7</i> in Siblings With Hereditary Motor Neuropathy.Neurol Genet2023
37403209ATF2 orchestrates macrophage differentiation and activation to promote antibacterial responses.J Leukoc Biol2023
34588632Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10<sup>-/-</sup> model of colitis.Cell Death Differ2022
35373586Jean Himms-Hagen, D.Phil. (1933-2021): Pioneering research in brown adipose tissue thermogenesis.Am J Physiol Endocrinol Metab2022
35668443Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers.J Ovarian Res2022
35965199Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity.EBioMedicine2022
35892309Targeting skeletal muscle mitochondrial health in obesity.Clin Sci (Lond)2022
35293095Association of muscle fiber type with measures of obesity: A systematic review.Obes Rev2022
32462687Effects of cobalt and chromium ions on glycolytic flux and the stabilization of hypoxia-inducible factor-1α in macrophages in vitro.J Orthop Res2021
33545428SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease.Cell Mol Gastroenterol Hepatol2021
33762963<i>Grx2</i> Regulates Skeletal Muscle Mitochondrial Structure and Autophagy.Front Physiol2021
33819356Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role.FASEB J2021
33645254Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women.Am J Physiol Endocrinol Metab2021
34815412Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1.Nat Commun2021
34483339A recurrent de novo ATP5F1A substitution associated with neonatal complex V deficiency.Eur J Hum Genet2021
34684467Dietary Cocoa Flavanols Enhance Mitochondrial Function in Skeletal Muscle and Modify Whole-Body Metabolism in Healthy Mice.Nutrients2021
34298618Nuclear HKII-P-p53 (Ser15) Interaction is a Prognostic Biomarker for Chemoresponsiveness and Glycolytic Regulation in Epithelial Ovarian Cancer.Cancers (Basel)2021
34337661Interindividual variability in weight loss in the treatment of obesity.Am J Clin Nutr2021
33442950The lifecycle of skeletal muscle mitochondria in obesity.Obes Rev2021
33002579Glutaredoxin-2 and Sirtuin-3 deficiencies impair cardiac mitochondrial energetics but their effects are not additive.Biochim Biophys Acta Mol Basis Dis2021
32926942Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production.Biochim Biophys Acta Mol Cell Res2021
32371858MCL-1<sup>Matrix</sup> maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions.Cell Death Dis2020
33033401Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.Nat Metab2020
33253187Phenomic screen identifies a role for the yeast lysine acetyltransferase NuA4 in the control of Bcy1 subcellular localization, glycogen biosynthesis, and mitochondrial morphology.PLoS Genet2020
33050144Role of Glutathione in Cancer: From Mechanisms to Therapies.Biomolecules2020
33070627Innate Immune Nod1/RIP2 Signaling Is Essential for Cardiac Hypertrophy but Requires Mitochondrial Antiviral Signaling Protein for Signal Transductions and Energy Balance.Circulation2020
33035570Factors affecting weight loss variability in obesity.Metabolism2020
32989316RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.Nat Metab2020
32869956Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women.Physiol Rep2020
32527767<i>SGCG</i> rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program.Diabetes2020
32175678Harnessing the protective role of OPA1 in diabetic cardiomyopathy.Acta Physiol (Oxf)2020
32492067A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma.PLoS Comput Biol2020
30659802Skeletal muscle mitoflashes, pH, and the role of uncoupling protein-3.Arch Biochem Biophys2019
30146472Atrial Fibrillation Is Associated With Impaired Atrial Mitochondrial Energetics and Supercomplex Formation in Adults With Type 2 Diabetes.Can J Diabetes2019
31581846Maternal diet-induced obesity alters muscle mitochondrial function in offspring without changing insulin sensitivity.FASEB J2019
31534514Glyoxalase 1 Prevents Chronic Hyperglycemia Induced Heart-Explant Derived Cell Dysfunction.Theranostics2019
30715214Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of cardiometabolic phenotypes.Cardiovasc Res2019
30710084Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.Nat Commun2019
31060926SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1.Mol Metab2019
31112400Mitochondrial adaptation in human mesenchymal stem cells following ionizing radiation.FASEB J2019
30448294IL-15 improves skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation.Biochim Biophys Acta Gen Subj2019
28800932Is Type 2 Diabetes in Adults Associated With Impaired Capacity for Weight Loss?Can J Diabetes2018
30144138Effects of cobalt and chromium ions on oxidative stress and energy metabolism in macrophages in vitro.J Orthop Res2018
30603053Tumor metabolism regulating chemosensitivity in ovarian cancer.Genes Cancer2018
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Collaborators

Ruth McPherson
Co-authored papers 31
Chantal A Pileggi
University of Ottawa
Co-authored papers 14
Jian Ying Xuan
Zhuji Affiliated Hospital of Wenzhou Medical University
Co-authored papers 8
Oliver Fiehn
University of California davis
Co-authored papers 6
Michele Geoffrion
University of Ottawa Heart Institute
Co-authored papers 5
Katey J Rayner
University of Ottawa
Co-authored papers 5
John W Newman
University of California Davis
Co-authored papers 4
Markku Laakso
Co-authored papers 3
Kirsi H Pietiläinen
Co-authored papers 2
Kristin Baetz
Ottawa Institute of Systems Biology, University of Ottawa, University of Calgary
Co-authored papers 2
Aldons J Lusis
Co-authored papers 2
P??ivi Pajukanta
David Geffen School of Medicine at university of california los angeles
Co-authored papers 2
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Hugh J McMillan
Montreal Children's Hospital, McGill University
Co-authored papers 2
Kym M Boycott
Children's Hospital of Eastern Ontario
Co-authored papers 2
Marcus Alvarez
David Geffen School of Medicine at university of california los angeles
Co-authored papers 2
Kathryn J Moore
Co-authored papers 1
Carl D Langefeld
Wake Forest University School of Medicine
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Ragunath Singaravelu
Ottawa Hospital Research Institute
Co-authored papers 1
William L Stanford
Ottawa Hospital Research Institute
Co-authored papers 1
Nadav Ahituv
University of California san francisco
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Michel L Tremblay
Co-authored papers 1
Carole Doré
Co-authored papers 1
Peter P Liu
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
Norman E Davey
The Institute of Cancer Research
Co-authored papers 1
Alexandre F R Stewart
Co-authored papers 1
Rajaa Sebaa
Co-authored papers 1
Release 1.2